Richard (Thomas Jane), Ron (Jeremy Piven), Jonathan (Rob Lowe) and Tim (Christian McKay) are old college buddies who gather for a week each year in Big Sur to celebrate Tim’s birthday and catch up with each other’s lives. On the surface, they look like typical men in their forties, with careers, families and responsibilities. But as with most people, there is more to them than meets the eye.

As the week progresses, they go down the rabbit hole of excess: mountains of drugs are consumed to a blaring rock 'n' roll soundtrack, parties with much younger women spin out of control. Exhausted and run ragged, they bare their souls and their reunion takes a much darker turn. When a promise from their past is brought to light, none of their lives will ever be the same. From director Mark Pellington, I MELT WITH YOU is a visually dazzling, wild and woolly trip deep into the male psyche, driven by four amazingly committed and profound performances from Thomas Jane, Jeremy Piven, Rob Lowe and Christian McKay.