52 min

#91 Nutrition, pathophysiology of DMT2, the environment and ending the diet wars The GP Show

    • Medicine

This episode is to supplement my interview with Dr David Unwin and is just with me reviewing and discussing some areas in more detail that David and I ran out of time to cover, including:
Pathophysiology of DMT2 and different dietary considerations Environmental and farming practices Ending the Diet Wars Some further reading for those that want it:
Environmental considerations: https://www.lifestylemedicine.org.au/content/is-the-path-to-health-the-same-path-to-environmental-sustainability/
Nutrition: Principles Before Position Part 3: The externalities of our food choices https://thegpshow.com/musings/pntpart3/ 
University of Oxford Grazed and Confused report: https://www.oxfordmartin.ox.ac.uk/downloads/reports/fcrn_gnc_report.pdf 
UK Sustainable Food Trust: https://sustainablefoodtrust.org/articles/grazed-and-confused-an-initial-response-from-the-sustainable-food-trust/
EAT Lancet: https://eatforum.org/ and https://www.thelancet.com/journals/lanplh/article/PIIS2542-5196(20)30055-3/fulltext 
2019 Nutrition Therapy for Adults With Diabetes or Prediabetes: A Consensus Report from the American Diabetes Association https://care.diabetesjournals.org/content/diacare/early/2019/04/10/dci19-0014.full.pdf
Diabetes Australia position statement on low carb approaches https://static.diabetesaustralia.com.au/s/fileassets/diabetes-australia/dbd70857-a834-45b0-b6f1-ea2582bbe5c7.pdf
Metabolic ward studies/randomised controlled feeding studies on various dietary composition:
https://www.ncbi.nlm.nih.gov/pubmed/29844096
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951141/
Other paper on dietary composition: https://jim.bmj.com/content/65/8/1102
Five Stages of Evolving Beta-Cell Dysfunction During Progression to Diabetes https://diabetes.diabetesjournals.org/content/53/suppl_3/S16
Combination of saturated fats with high GI carbs causing further disease that saturated fats alone in "Saturated fat, carbohydrates and cardiovascular disease", 2011 https://www.ncbi.nlm.nih.gov/pubmed/21978979
Insulinogenic response of foods https://www.ncbi.nlm.nih.gov/pubmed/9356547
Personalized Nutrition by Prediction of Glycemic Responses https://www.ncbi.nlm.nih.gov/pubmed/26590418
Dietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis (observational) https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(18)30135-X/fulltext
High/low animal protein diets and CVD:
https://www.ncbi.nlm.nih.gov/pubmed/11108325
Dr Ornish Lifestyle Heart Disease Reversal study https://www.ncbi.nlm.nih.gov/pubmed/9863851
Other potentials for low carb approaches:
The Therapeutic Potential of Ketogenic Diet Throughout Life: Focus on Metabolic, Neurodevelopmental and Neurodegenerative Disorders, 2019, Professor Sarnyai et al  https://www.ncbi.nlm.nih.gov/pubmed/31493223
Adherence to diets: 
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302176/
https://pubmed.ncbi.nlm.nih.gov/29522789/ 
https://www.mdpi.com/2072-6643/12/5/1251 
 
Enjoy friends
 

This episode is to supplement my interview with Dr David Unwin and is just with me reviewing and discussing some areas in more detail that David and I ran out of time to cover, including:
Pathophysiology of DMT2 and different dietary considerations Environmental and farming practices Ending the Diet Wars Some further reading for those that want it:
Environmental considerations: https://www.lifestylemedicine.org.au/content/is-the-path-to-health-the-same-path-to-environmental-sustainability/
Nutrition: Principles Before Position Part 3: The externalities of our food choices https://thegpshow.com/musings/pntpart3/ 
University of Oxford Grazed and Confused report: https://www.oxfordmartin.ox.ac.uk/downloads/reports/fcrn_gnc_report.pdf 
UK Sustainable Food Trust: https://sustainablefoodtrust.org/articles/grazed-and-confused-an-initial-response-from-the-sustainable-food-trust/
EAT Lancet: https://eatforum.org/ and https://www.thelancet.com/journals/lanplh/article/PIIS2542-5196(20)30055-3/fulltext 
2019 Nutrition Therapy for Adults With Diabetes or Prediabetes: A Consensus Report from the American Diabetes Association https://care.diabetesjournals.org/content/diacare/early/2019/04/10/dci19-0014.full.pdf
Diabetes Australia position statement on low carb approaches https://static.diabetesaustralia.com.au/s/fileassets/diabetes-australia/dbd70857-a834-45b0-b6f1-ea2582bbe5c7.pdf
Metabolic ward studies/randomised controlled feeding studies on various dietary composition:
https://www.ncbi.nlm.nih.gov/pubmed/29844096
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951141/
Other paper on dietary composition: https://jim.bmj.com/content/65/8/1102
Five Stages of Evolving Beta-Cell Dysfunction During Progression to Diabetes https://diabetes.diabetesjournals.org/content/53/suppl_3/S16
Combination of saturated fats with high GI carbs causing further disease that saturated fats alone in "Saturated fat, carbohydrates and cardiovascular disease", 2011 https://www.ncbi.nlm.nih.gov/pubmed/21978979
Insulinogenic response of foods https://www.ncbi.nlm.nih.gov/pubmed/9356547
Personalized Nutrition by Prediction of Glycemic Responses https://www.ncbi.nlm.nih.gov/pubmed/26590418
Dietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis (observational) https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(18)30135-X/fulltext
High/low animal protein diets and CVD:
https://www.ncbi.nlm.nih.gov/pubmed/11108325
Dr Ornish Lifestyle Heart Disease Reversal study https://www.ncbi.nlm.nih.gov/pubmed/9863851
Other potentials for low carb approaches:
The Therapeutic Potential of Ketogenic Diet Throughout Life: Focus on Metabolic, Neurodevelopmental and Neurodegenerative Disorders, 2019, Professor Sarnyai et al  https://www.ncbi.nlm.nih.gov/pubmed/31493223
Adherence to diets: 
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302176/
https://pubmed.ncbi.nlm.nih.gov/29522789/ 
https://www.mdpi.com/2072-6643/12/5/1251 
 
Enjoy friends
 

52 min