GTG 73: Care of Women Presenting with Suspected PPROM from 24+0 Weeks of Gestation RCOG

This guideline comprises recommendations relating to the diagnosis, assessment, care and timing of birth of women presenting with suspected PPROM from 24+0 to 36+6 weeks of gestation. It also addresses care in a subsequent pregnancy.

1. Key recommendations (01:07)

2. Background and scope (03:35)

3. Identification and assessment of evidence (04:45)

4. Diagnosis (05:27)

4.1 How is the diagnosis of PPROM made? (05:30)

5. Assessment (10:54)

5.1 What is required antenatally to identify infection? (10:58)

5.2 Should neonatologists be included in the woman's care? (15:10)

6. Management (16:58)

6.1 Should antibiotics be given? (17:00)

6.2 What is the role of antenatal corticosteroids? (20:09)

6.3 What is the role of magnesium sulfate for neuroprotection of the baby? (25:30)

6.4 Should tocolytic agents be used? (28:17)

6.5 Can women be monitored at home? (30:22)

6.6 Is there a role for amnioinfusion in PPROM? (35:35)

6.7 Should women with PPROM be offered emotional support? (37:34)

7. Birth (39:02)

7.1 When is the appropriate time to deliver the baby? (39:05)

8. Care in a subsequent pregnancy following PPROM (44:26)

8.1 Who should care for a the woman in a subsequent pregnancy? (44:32)

9. Recommendations for future research (46:45)

10. Auditable topics (47:49)

Disclosures of interest (49:18)

Funding (49:35)

Supporting information (50:13)

References (51:03)