This episode is all about the pain. What is pain, why do we experience it and is it ever useful? We talk with Dr Joseph Kluver, a specialist pain physician, about how pain works and what happens when pain stops being acute and becomes a chronic problem. He explains how he works with patients who have persistent pain and the therapies that can lead to long-term change in their lives. We also talk to Sara Shams, who is a bilateral through-knee amputee, about her experience with phantom limb pain after she had her amputations, and the other types of pain people with amputations can live with every day.