The Doctor's Farmacy with Mark Hyman, M.D‪.‬ Dr. Hyman+

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Like most things in life, when it comes to optimizing metabolic health, a nuanced perspective can help. Rather than viewing it as a black-and-white issue, we can take into consideration the big-picture social context we’re facing that encourages ultra-processed foods, obesity, and lifelong medication as well as the micro-level of what people are experiencing as individuals and understanding how to help them when all else fails. Today I’m thrilled to sit down with Dr. Tyna Moore and Calley Means for a grounded discussion that explores both sides of the spectrum, and everything in between. 
In this episode, we discuss:

The controversial discussion of GLP-1 agonists like Ozempic, weighing the pros and cons of these new drugs in treating obesity and metabolic crises (3:34)

Challenging the notion of treating obesity with drugs like Ozempic (10:35)

An unsettling revelation about the push for using Ozempic in children (12:04)

Digging deeper into GLP-1 research and some of the benefits (32:51)

Why are children being born metabolically challenged? (41:11)

Dr. Moore’s approach to using peptides with her patients and for her own crippling pain, and what they’ve seen (45:19)

How our current healthcare system lacks policies and support for behavior change (1:27)


While there are always differing views, we know for sure that our food and drug policies aren’t serving the best interests of creating sustainable, empowered health for the masses. I hope you’ll tune in to hear more from this comprehensive and lively discussion. 

This episode is brought to you by Rupa Health, Pendulum, ARMRA Colostrum, and One Skin.
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Gas, bloating, constipation, diarrhea, urgency, and painful cramping—these are just some of the many difficult symptoms that come along with inflammatory bowel disease, also known as IBD. This disorder is an umbrella term for a variety of symptoms and diagnoses, including ulcerative colitis and Crohn’s disease, and it impacts millions of Americans each day.
In this episode, Dr. Hyman speaks with Dr. George Papanicolaou, Dr. Miguel Reguiro, and Dr. Shilpa Ravella about the Functional Medicine approach to reducing symptoms of IBD that extend beyond medications and surgery.
This episode is brought to you by Rupa Health and LMNT.
Streamline your lab orders with Rupa Health. Access more than 3,000 specialty lab tests and register for a FREE live demo at RupaHealth.com.
LMNT is giving listeners a FREE eight-count sample pack of their vital electrolyte drink mix with any purchase. Just visit DrinkLMNT.com/Hyman today.

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In the health space, we hear the term ultra-processed foods thrown around often for its clear link to chronic diseases such as depression, Alzheimer’s, and diabesity. But what exactly does “ultra-processed” mean? How can you tell if a food is ultra-processed?

In today’s Health Bites episode, we will learn exactly what ultra-processed foods are, how to identify them, their impact on human health, and the global economy. We’ll also discuss tips and tricks for how to read food labels to better navigate the grocery store, and the innovations happening in Washington to develop label laws that helps protect the consumer.

In this episode, I discuss:

Definition, examples, and deceptive health claims of ultra-processed food (2:06) 

Health risks and impacts of ultra-processed food (7:30) 

Case study: impact of an ultra-processed diet on twin girls (10:00) 

History and rise of processed food (12:09) 

Difference between ultra-processed and minimally processed foods (17:45) 

Impact of food packaging and additives on health (24:01) 

Economic and societal consequences of chronic diseases caused by poor diet (28:04) 

Identifying ultra-processed foods and understanding food labeling (35:00) 

Avoiding ultra-processed foods and using food scoring systems (40:50) 


This episode is brought to you by Rupa Health, Essentia, and Cymbiotika.

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Receive an extra $100 off your mattress purchase! Go to myessentia.com/drmarkhyman and use code HYMAN at checkout to get this great deal.

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The prevalence of autism has risen a shocking 400% in the last twenty years. Increased awareness and diagnosis are one piece, but there are also so many other factors to consider. The hopeful news is that we’re seeing a shift paradigm in how we view and treat autism, with some truly amazing improvements possible. I’m thrilled to welcome Dr. Suzanna Goh, a board-certified pediatric behavioral neurologist, behavioral analyst, neuroscience researcher, Rhodes scholar, and author.

In this episode, we discuss:


Shaking things up around the autism paradigm (1:57)

The connection between the brain and mitochondria (6:04)

Can autism be reversed? (7:00)

The biggest mistake made in autism (10:10)

What creates the inflammatory fire in the autistic brain? (15:20)

The role of diet in autism treatment (19:17)

Functional tests for assessing brain function and how to best support kids with autism (26:30)

Mitochondrial dysfunction and autism (28:30)

"Magnificent Minds" - A book on autism by Dr. Suzanne Goh (34:57)


Using a whole-child approach and investigating the intricate connections between metabolism, mitochondrial function, and nutrition we can better understand what types of support autistic children need most. I hope you’ll listen in to learn more. 

This episode is brought to you by Rupa Health, AG1, and Essentia.

Streamline your lab orders with Rupa Health. Access more than 3,000 specialty lab tests and register for a FREE live demo at RupaHealth.com.

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Our global mental health crisis is growing at an exponential rate, with over half a billion people suffering from depression and anxiety; it’s time we rethink our understanding of the underlying root causes of mental health challenges.

From treating thousands of patients, I’ve learned that depression is not in your head. It’s in your body. More specifically, your gut. When your gut is unhealthy and inflamed, your brain is unhealthy and inflamed. In Functional Medicine, we know that the gut and the brain are intimately connected and that the health of one directly influences the health of the other. 

In today’s Health Bites episode, we’re diving into the gut-brain connection and sharing Functional Medicine tools to support your gut health and, as a result, your mood and mental health. 

In this episode, I discuss:

Our global mental health crisis (2:45)

The gut-brain connection (4:18)

The story of Marks's broken brain (5:15)

Features of the gut-brain axis (8:57)

Gut hormones that send signals to your brain (10:06)

Role of the gut microbiota in mood and mental health (12:24)

How stress negatively impacts our gut microbiome (20:14)

The link between leaky gut and poor mental health (21:41)

The Functional Medicine approach to fixing the gut (25:56)

The 5R Program for fixing your gut health (30:09)


This episode is brought to you by AG1 and Rupa Health.

Get your daily serving of vitamins, minerals, adaptogens, and more with AG1. Head to DrinkAG1.com/Hyman and get 10 FREE travel packs + FREE Welcome Kit with your first order.

Streamline your lab orders with Rupa Health. Access more than 3,000 specialty lab tests and register for a FREE live demo at RupaHealth.com.

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Functional Medicine offers patients many things, especially hope and understanding. Autoimmune disease is a prime example: Rather than condemning patients to a lifetime of symptom management through medication, functional practitioners dig to find the “why,” to address the underlying causes with individualized, multimodal support to create lasting improvement and systemic healing. My guest today, Dr. Sara Gottfried, is a physician, researcher, author, and educator passionate about changing the way we view and treat autoimmunity. 

In this episode, we discuss:


What is a “trauma signature” and what is its role in autoimmunity? (5:55)

Hidden autoimmunity triggers you might be surprised to learn about (21:30)

The go-to test panel Sara runs on her patients (27:33)

Sara’s stack for reducing cortisol and why trauma has to be considered (39:00)

How Trauma biologically impacts you through the PINE system (41:40)

Psychedelic therapy and other healing states of consciousness, plus Sara’s personal experience using them (48:10)

What Sara wishes she told her 20-year-old self about life (1:15:45)


When we dig deeper, we always find out there is more going on below the surface. I know you’ll love this conversation as much as I did. 

This episode is brought to you by Rupa Health, Cozy Earth, and Magnesium Breakthrough. 

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