100 episodes

Author interviews that explore the latest clinical reviews.

JAMA Clinical Reviews JAMA Network

    • Medicine

Author interviews that explore the latest clinical reviews.

    The 2020 Influenza Epidemic—More Serious Than Coronavirus in the US

    The 2020 Influenza Epidemic—More Serious Than Coronavirus in the US

    Although coronavirus disease 2019 (COVID-19) dominates the news in early 2020, it affects few people in the US. In contrast, at the same time the US is experiencing a severe influenza epidemic, which has caused an estimated 250 000 hospitalizations and 14 000 deaths. Timothy Uyeki, MD, lead for the CDC’s 2019 novel coronavirus response team and Chief Medical Officer of CDC’s influenza division, discusses influenza in the US, how it compares to coronavirus, and what both patients and clinicians should know about this year’s flu season.
    CDC's Influence site
    CDC's Weekly U.S. Influenza Surveillance Report
    HealthMap Vaccine Finder

    • 31 min
    AIDS-Related Chronic Inflammation Leading to Chronic Disease

    AIDS-Related Chronic Inflammation Leading to Chronic Disease

    Great strides have been made in treating HIV, as Anthony Fauci, MD, discusses in this podcast episode. But even substantial viral suppression leaves some virus behind, causing chronic inflammation. Many chronic diseases, including atherosclerotic coronary vascular disease, are worsened by this chronic inflammatory state. Because HIV patients are now living very long lives, they are also developing chronic diseases at a more rapid rate than their non-HIV-infected peers because of this chronic inflammation.

    • 9 min
    Parkinson Disease

    Parkinson Disease

    More than 6 million people worldwide have Parkinson disease. Even though it is classically associated with tremors, the disease has many manifestations and is very treatable for most patients. Michael S. Okun, MD, from the Department of Neurology at the University of Florida, Gainesville, discusses the pathophysiology, clinical presentation, diagnosis, and treatment of Parkinson disease.
    Related article:
    Parkinson Disease
    AMA Manual of Style

    • 26 min
    Testing for Breast Cancer Susceptibility Genes

    Testing for Breast Cancer Susceptibility Genes

    Breast cancer is a leading cause of death in women. Some women have a cancer susceptibility gene known as BRCA, and women should be tested for BRCA under some circumstances. Carol Mangione, MD, division chief of General Internal Medicine and Health Services Research at UCLA, discusses when testing is appropriate, and Ranjit Manchanda, MD, PhD, from Barts Cancer Institute in London, UK, discusses the cost-effectiveness of BRCA screening for women who have had breast cancer.

    • 13 min
    Management of Chronic Stable Angina in 2020

    Management of Chronic Stable Angina in 2020

    Controversy exists regarding how to best manage chronic stable angina. Intuitively, it seems that because it is usually caused by coronary artery lesions, addressing those lesions either via percutaneous coronary angiography or coronary artery bypass operations would be the best way to manage this problem. Several studies have suggested that this is not the case and that results of these interventions are no better than optimal medical management. Recently, a very large trial examining this clinical question has provided results suggesting that any approach works about the same. We interviewed Donald Lloyd-Jones, MD, chair of the department of preventive medicine at Northwestern University, during the recent American Heart Association meeting about this issue.
    Related articles:
    Baseline Characteristics and Risk Profiles of Participants in the ISCHEMIA Randomized Clinical Trial
    Does This Patient With Chest Pain Have Acute Coronary Syndrome?: The Rational Clinical Examination Systematic Review
    Coronary Microvascular Dysfunction Causing Cardiac Ischemia in Women
    Acupuncture as Adjunctive Therapy for Chronic Stable Angina: A Randomized Clinical Trial

    • 7 min
    Treating Conjunctivitis and Dry Eye Disease

    Treating Conjunctivitis and Dry Eye Disease

    Conjunctivitis and dry eye disease are some of the most common conditions patients present with. They are usually benign entities that respond well to conservative measures and usually don’t require medications. However, if medications are necessary, clinicians can find a comprehensive assessment of these drugs recently published in the December 2, 2019, issue of The Medical Letter. An excerpt from this article summarizing information about conjunctivitis and dry eye disease was published in the February 4, 2020 issue of JAMA. Kathryn Colby, MD, PhD, chair of the Department of Ophthalmology & Visual Science at the University of Chicago, explains in this podcast how to treat conjunctivitis and dry eye disease.

    • 18 min

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