25 min
Sneaky Parasites with Dr. Glover Research In Review
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- Life Sciences
African Trypanosomiasis caused by the parasite Trypanosoma brucei affects thousands in endemic regions. T. brucei can linger in the bloodstream for lengthy periods of time due to its ability to change its glycoprotein coat regularly to hide from the immune system. This episode's guest studies the molecular mechanisms of how this sneaky parasite is able to hide in the immune system.
Paper available here: DNA double-strand break position leads to distinct gene expression changes and regulates VSG switching pathway choice - PMC (nih.gov)
African Trypanosomiasis caused by the parasite Trypanosoma brucei affects thousands in endemic regions. T. brucei can linger in the bloodstream for lengthy periods of time due to its ability to change its glycoprotein coat regularly to hide from the immune system. This episode's guest studies the molecular mechanisms of how this sneaky parasite is able to hide in the immune system.
Paper available here: DNA double-strand break position leads to distinct gene expression changes and regulates VSG switching pathway choice - PMC (nih.gov)
25 min