Expansion von T-Zellen seltener Spezifität mittels B-Zellen Fakultät für Chemie und Pharmazie - Digitale Hochschulschriften der LMU - Teil 01/06

    • Educación

I concentrated on the expansion of T cells specific against the oncogenic human papilloma virus 16 (HPV16), which are a very rare population in the blood of healthy donors as well as patients with HPV16-associated cancer. Instead of mature dendritic cells (DC) as antigen presenting cells, which are a potent but limitated system, I used activated B cells.

I was able to expand cytotoxic active HPV-specific T cells to therapeutically relevant cell numbers. I analysed the T cell receptors of the E7-specific T cells well as their avidity to get a first idea of clonality and avidity of HPV-specific T cell pools.

I concentrated on the expansion of T cells specific against the oncogenic human papilloma virus 16 (HPV16), which are a very rare population in the blood of healthy donors as well as patients with HPV16-associated cancer. Instead of mature dendritic cells (DC) as antigen presenting cells, which are a potent but limitated system, I used activated B cells.

I was able to expand cytotoxic active HPV-specific T cells to therapeutically relevant cell numbers. I analysed the T cell receptors of the E7-specific T cells well as their avidity to get a first idea of clonality and avidity of HPV-specific T cell pools.

Top podcasts en Educación

TED Talks Daily
TED
Black Mango Podcast
Black Mango
The Mel Robbins Podcast
Mel Robbins
anything goes with emma chamberlain
emma chamberlain
Aman Kanwal Sidhu
Aman Kanwal Sidhu
Inglés desde cero
Daniel

Más de Ludwig-Maximilians-Universität München

LMU Rechenmethoden 2012/2013
Prof. Dr. Jan von Delft
GK Strafrecht II (A-K) SoSe 2020 Satzger
Helmut Satzger
NANO-BIO-PHYSICS SYMPOSIUM 07.09.2019 Day 2
Ludwig-Maximilians-Universität München
NANO-BIO-PHYSICS SYMPOSIUM 06.09.2019 Day 1
Ludwig-Maximilians-Universität München
Center for Advanced Studies (CAS) Research Focus Global Health
Center for Advanced Studies
The Wicked Mu
Stephan Kulla und Nils Hansen