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This piece focuses upon the Hypotension Predictive Index (HPI) technology. We look at the validation process of HPI, addressing criticisms and clarifying its predictive ability for hemodynamic instability. How important is it to understand the underlying causes of instability rather than solely relying on blood pressure readings? What is the role of HPI in early detection and proactive management? The discussion also touches on the limitations of traditional mean arterial pressure (MAP) monitoring and the need for a holistic approach to hemodynamic assessment.
Presented by Desiree Chappell, TopMedTalk’s co-editor in Chief, speaking with Monty Mythen, Senior Vice President Medical Affairs, Edwards Lifesciences, Critical Care, Emeritus Professor of Anaesthesia and Critical Care, University College London, Thomas Sheeran, Senior Director Medical Affairs, Edwards Lifesciences, and Simon Davies, Consultant Anaesthetist at York Teaching Hospital NHS Foundation Trust.
The paper 'Comparison of Differences in Cohort (Forward) and Case Control (Backward) Methodological Approaches for Validation of the Hypotension Prediction Index' is here: https://pubs.asahq.org/anesthesiology/article/doi/10.1097/ALN.0000000000004989/139987/Comparison-of-Differences-in-Cohort-Forward-and?searchresult=1
Here’s the link to the Physiology Lab section of last year’s ASA symposium on YouTube: https://youtu.be/yfl1VMMgIRs?si=YxGfOs-pdlIVVGt1
Here are publications relating HPI to hemodynamic instability at a microcirculation level:
https://pubmed.ncbi.nlm.nih.gov/33755645/
https://pubmed.ncbi.nlm.nih.gov/36335548/

It’s one of our busiest times of the year. This piece is the first of a series from The 7th Collaborative Clinical Trials in Anaesthesiology Conference, Prato, Italy.
Presented by Desiree Chappell and her co-hosts; Mike Grocott, Monty Mythen, Andy Cumpstey and Kate Leslie.
Please ensure you are subscribed to TopMedTalk and check back regularly as we have more from this conference (and others) to come.
We mention our piece with Paul Myles, you can listen to it here: https://topmedtalk.libsyn.com/prato-2019-paul-myles

This piece is part of our coverage of The International Anesthesia Research Society (IARS) annual meeting.
This wide ranging conversation tackles hemodynamics, intraoperative hypotension and its implications. We also discuss finance for medical practitioners and patient-centered research.
Presented by Desiree Chappell, Vice President of Clinical Quality at NorthStar Anesthesia and TopMedTalk co-editor in Chief and Monty Mythen, TopMedTalk’s founder and Senior Vice President Medical Affairs, Edwards Lifesciences with their guest Wael Saasouh, Anesthesiologist and Director of Research for NorthStar Anesthesia.

This piece is part of our coverage of The International Anesthesia Research Society (IARS) annual meeting.
Hear us discuss the prestigious journal "Anesthesia and Analgesia", affiliated with the International Anesthesia Research Society (IARS). Listen to how it maintains its status as one of the top-ranked journals in its field, the importance of its readability and accessibility. Learn about the journal’s rapid review process and diverse editorial board that reflects global and thematic diversity. Also; transitioning to digital formats, the evolving nature of manuscript submissions, the integration of AI and the journal's commitment to gender and intellectual diversity.
We also discuss peer review workshops and an editorial fellowship scheme, allowing early career researchers to learn about manuscript handling and review.
Visit the online edition here: https://journals.lww.com/anesthesia-analgesia/pages/default.aspx
Presented by Desiree Chappell, TopMedTalk co-editor in Chief and Monty Mythen, TopMedTalk’s founder with Jaideep Pandit, Professor of Anaesthesia, University of Oxford and Editor-in-Chief, “Anesthesia and Analgesia”.

Euroanaesthesia is recognised worldwide as one of the most important and influential annual congresses in anaesthesiology and intensive care. This year, TopMedTalk is there in Munich, Germany, bringing you exclusive coverage.
This conversation focuses upon perioperative neurocognitive disorders and the significance of biomarkers in predicting and managing these conditions.
The paper mentioned, “Examining Subjective Psychological Experiences of Postoperative Delirium in Older Cardiac Surgery Patients” is here: https://pubmed.ncbi.nlm.nih.gov/36201368/
Audre Curtis’s experiences on YouTube are interesting: https://www.youtube.com/watch?v=CHA2Hzg5Kkk
And the American Geriatrics Society is here: https://www.americangeriatrics.org/
Presented by Desiree Chappell and Kate Leslie with their guests David Scott, Professor, University of Melbourne and Lis Evered, Associate Professor of Neuroscience in Anaesthesiology at Weill Cornell Medicine, Scientific Head of Research in the Department of Anaesthesia and Acute Pain Medicine at St. Vincent’s Hospital in Melbourne, Australia, Associate professor at the University of Melbourne.

This talk “Respiratory Prehabilitation” was originally given at The World Congress of Prehabilitation in London by Linda Denehy, Head of the Melbourne School of Health Sciences and Professor of Physiotherapy at The University of Melbourne, Australia
It is the third in a series of talks given under the title, “Non-cancer Prehabilitation”, which also includes a fascinating panel discussion. The first talk is available for you to listen to here: https://topmedtalk.libsyn.com/prehabilitation-in-aneurysm-surgery-prehab-world-congress
The second talk was published here: https://topmedtalk.libsyn.com/cardiac-prehabilitation-trial-prehab-world-congress
Ensure you are subscribed to TopMedTalk to guarantee you get to hear the full series.