18 episodes

On this podcast, Christina Applegate and Jamie-Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.

MeSsy with Christina Applegate & Jamie-Lynn Sigler Wishbone Production

    • Society & Culture
    • 4.9 • 255 Ratings

On this podcast, Christina Applegate and Jamie-Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.

    Will Ferrell

    Will Ferrell

    This week, on the 20th anniversary of “Anchorman,” Christina and Jamie are joined by Will Ferrell. They share memories from filming the movie and discuss how Will got into comedy, SNL, and more.

    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    This show is sponsored by:
    BetterHelp: This episode is sponsored by/brought to you by BetterHelp. Give online therapy a try at betterhelp.com/MESSY and get on your way to being your best self.

    Vuori: MeSsy listeners get 20% off your FIRST purchase. Get yourself some of the most comfortable and versatile clothing on the planet at vuori.com/MESSY and enjoy free shipping on any U.S. orders over $75 and free returns. 

    Babbel: Right now get up to 60% off your Babbel subscription - but only for our listeners - at Babbel.com/MESSY  Rules and restrictions may apply.

    Fatty15: Fatty15 is on a mission to replenish your C15 levels and restore your long-term health.  You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/messy and using code MESSY at checkout. 

    • 1 hr 25 min
    The Only Guarantee in Life Is Change

    The Only Guarantee in Life Is Change

    This week, Christina and Jamie discuss the ups and downs of living with a chronic illness, acceptance, the importance of paying attention to your body, and much more.
    This episode was recorded in early 2024.

    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    This episode is sponsored by:
    Cionic: MeSsy listeners can get $50 off by entering the code MESSY during checkout Visit cionic.com/messy 
    MudWtr: For a limited time, our listeners get up to 43% off your entire order, Free Shipping and a Free Rechargeable Frother when you use our exclusive link. Head to mudwtr.com/MESSY and grab your starter kit!
    ZocDoc: Go to Zocdoc.com/MESSY and download the Zocdoc app for FREE. Then find and book a top-rated doctor today.
    Jenni Kayne: Find your forever pieces @jennikayne and get 15% off with promo code MESSY15 at jennikayne.com/MESSY15! #jennikaynepartner

    • 1 hr 5 min
    Sadie

    Sadie

    This week, Christina and Jamie are joined by a very special guest... Christina's daughter Sadie. She opens up about some of her own health challenges, what it's like to be the daughter of someone with MS, what it's like to be a thirteen year old right now, and much more.
    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    This episode is sponsored by:
    Vuori - Go to vuori.com/MESSY
    One Skin - For a limited time, you can try OneSkin for 15% off using the code MESSY at oneskin.co
    AG1 - drinkag1.com/messy

    • 1 hr 1 min
    Sh*t Happens

    Sh*t Happens

    This week, Christina and Jamie discuss the importance of not holding things in, the stages of grief, finding people to lean on, and more.

    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    This episode is sponsored by:
    Cionic - MeSsy listeners can get $50 off by entering the code MESSY during checkout Visit cionic.com/messy 
    Honeylove - For a limited time only you can get Honeylove on sale. Get 20% Off your entire order with our exclusive link  honeylove.com/messy

    • 55 min
    Jennifer Esposito

    Jennifer Esposito

    This week, Christina and Jamie are joined by Jennifer Esposito. Jennifer opens up about her celiac disease and the struggle she went through to get a diagnosis. They also discuss the gaslighting of women, the importance of fighting for your health, her new film "Fresh Kills," and much more.

    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    This show is sponsored by:
    Vuori- Messy listeners get 20% off your FIRST purchase  at Vuori.com/MESSY and enjoy free shipping on any U.S. orders over $75 and free returns
    Fatty15- Fatty15 is on a mission to replenish your C15 levels and restore your long-term health.Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/MESSY and use code MESSY at checkout
    BetterHelp - Messy is sponsored by/brought to you by BetterHelp. Give online therapy a try at betterhelp.com/messy and get on your way to being your best self.
    Zoc Doc - Go to Zocdoc.com/MESSY and download the Zocdoc app for FREE. Then find and book a top-rated doctor today. 

    • 1 hr 5 min
    You Get What You Give

    You Get What You Give

    This week, Christina and Jamie discuss feeling trapped, missing high heels, their favorite shows that they’ve worked on, and more.
    This episode was recorded in early 2024.
    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    This episode is sponsored by:
    AG1 - Try AG1 and get a FREE 1-year supply of Vitamin D3K2 AND 5 free AG1 Travel Packs with your first purchase at drinkAG1.com/messy. That’s drinkAG1.com/messy.

    Lume - New customers GET 15% ALL Lume products with code MESSY- and if you combine the 15% off with the already discounted starter pack, that equals over 40% off their Starter Pack! Use code MESSY for 15% off your first purchase at LumeDeodorant.com. 

    BetterHelp - Messy is sponsored by/brought to you by BetterHelp. Give online therapy a try at betterhelp.com/messy and get on your way to being your best self.

    • 53 min

Customer Reviews

4.9 out of 5
255 Ratings

255 Ratings

H19692 ,

So honest

It’s Christina and Jamie-Lynn’s complete openness and honesty that I love. Absolutely nothing is off the table in their conversations. They’re bringing us into their lives in dealing with MS through every day. Despite not having MS myself, I deal with a nerve pain issue and this has made me feel completely seen in my own struggles. Love you ladies!!

Kat Finnerty ,

Two incredible Masters of Disaster!

I really love how you girls haven’t let your good disaster go to waste. You share all your catastrophe’s with us and I, for the most part, resonate with your messy lives.

It’s so helpful to hear a candid conversation that is often amusing and light and not heavy and depressing.

Keep spreading love and light and ‘Never Let a good disaster go to waste’

jedadya ,

Thank you from the bottom of my heart

I am so grateful to both of you. I live with rheumatoid arthritis. The struggle is real. The physical, emotional, social, journey has gone to the depths and found periods of relief. The wave is active every day. I truly anticipate with excitement and joy to hear each one of your episodes. My creative, resilient, joyous, curious soul has been dampened by this disease. I am in the process of learning acceptance and honesty. I am learning to live with unconditional love towards myself. It is really tough. Thank you for your honesty, transparency and authenticity.
Please keep talking and sharing. Keep it real!!
We can be whole and we can be loved and we can have value and we can have joy and we can contribute despite the illness .

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