27 min

Mice Don’t Menstruate: Reimagining Women’s Health Using Organ Chips with Dr. Donald Ingber Innovate and Elevate

    • Life Sciences

In this episode, Sharon is joined by Dr. Donald Ingber, Founding Director at Wyss Institute for Biologically Inspired Engineering at Harvard University. 
Dr. Ingber’s commitment to following his passion has led him to countless medical and technological breakthroughs, including organ-chip technology. These incredible chips recreate the structure and function of human organs. Drugs can be administered through organ-chips so that blood impact can be monitored. Once more widely adopted, organ-chip testing will be able to replace animal testing. As Dr. Ingber shares, the results will surpass those of animal testing.
The organ-chip technology already includes women’s health models and holds great promise to revolutionize this under-invested area. Because animals, namely mice, do not have menstrual cycles, their biological environments are already skewed to test any women’s health-related projects. Organ-chips are a great solution to close the data gap. Dr. Ingber shares two projects underway in partnership with the Gates Foundation: to create a cure for bacterial vaginosis and to create a non-hormonal contraceptive. 
Dr. Ingber highlights the importance of nurturing the business side of scientific breakthroughs so that innovations can reach patients. Twenty percent of Harvard’s intellectual property comes out of the Wyss Institute, and both funding and mentorship play crucial roles in that success metric.  
Episode Outline
(00:53) Meet Dr. Donald Inbger 
(02:11) Where Art Meets Science: Inside The Brilliant Mind of Dr. Ingber 
(07:08) What Is Organ-on-a-Chip Technology? 
(13:17) Reimaging Women’s Health with Organ-Chips
(21:11) Think Outside The Box: Bringing Innovation to Life 
Connect with Sharon
Connect with Sharon on LinkedIn: Sharon KedarLearn more about Innovate and Elevate innovateandelevatepodcast.comSubscribe to Innovate and Elevate on YouTubeJoin the newsletter to receive the latest episodes in your inbox: Innovate and Elevate Newsletter
Connect with Dr. Ingber
Follow The Wyss Institute on LinkedInLearn more about Emulate, Inc.
Additional Resources
The Wyss Institute The Wyss-Northpond Research And Innovation Alliance First rodent found with a human-like menstrual cycleThe White House Initiative on Women's Health Research
This podcast is produced by the women at The Wave Editing.

In this episode, Sharon is joined by Dr. Donald Ingber, Founding Director at Wyss Institute for Biologically Inspired Engineering at Harvard University. 
Dr. Ingber’s commitment to following his passion has led him to countless medical and technological breakthroughs, including organ-chip technology. These incredible chips recreate the structure and function of human organs. Drugs can be administered through organ-chips so that blood impact can be monitored. Once more widely adopted, organ-chip testing will be able to replace animal testing. As Dr. Ingber shares, the results will surpass those of animal testing.
The organ-chip technology already includes women’s health models and holds great promise to revolutionize this under-invested area. Because animals, namely mice, do not have menstrual cycles, their biological environments are already skewed to test any women’s health-related projects. Organ-chips are a great solution to close the data gap. Dr. Ingber shares two projects underway in partnership with the Gates Foundation: to create a cure for bacterial vaginosis and to create a non-hormonal contraceptive. 
Dr. Ingber highlights the importance of nurturing the business side of scientific breakthroughs so that innovations can reach patients. Twenty percent of Harvard’s intellectual property comes out of the Wyss Institute, and both funding and mentorship play crucial roles in that success metric.  
Episode Outline
(00:53) Meet Dr. Donald Inbger 
(02:11) Where Art Meets Science: Inside The Brilliant Mind of Dr. Ingber 
(07:08) What Is Organ-on-a-Chip Technology? 
(13:17) Reimaging Women’s Health with Organ-Chips
(21:11) Think Outside The Box: Bringing Innovation to Life 
Connect with Sharon
Connect with Sharon on LinkedIn: Sharon KedarLearn more about Innovate and Elevate innovateandelevatepodcast.comSubscribe to Innovate and Elevate on YouTubeJoin the newsletter to receive the latest episodes in your inbox: Innovate and Elevate Newsletter
Connect with Dr. Ingber
Follow The Wyss Institute on LinkedInLearn more about Emulate, Inc.
Additional Resources
The Wyss Institute The Wyss-Northpond Research And Innovation Alliance First rodent found with a human-like menstrual cycleThe White House Initiative on Women's Health Research
This podcast is produced by the women at The Wave Editing.

27 min