46 episodes

Join Drs. Brenda Raud and Jason Goldsmith as they discuss the latest in immunology research, and interview some of the greatest minds in the field.

The Immunology Podcast The Immunology Podcast

    • Science
    • 5.0 • 4 Ratings

Join Drs. Brenda Raud and Jason Goldsmith as they discuss the latest in immunology research, and interview some of the greatest minds in the field.

    Ep. 42: “Immune Mechanisms After Stroke” Featuring Dr. Arthur Liesz

    Ep. 42: “Immune Mechanisms After Stroke” Featuring Dr. Arthur Liesz

    Dr. Arthur Liesz is a Professor of Experimental Neurology at the University of Munich. The Liesz lab is interested in the interplay between the brain and the immune system after stroke. He talks about the inflammatory response to stroke, including T cell-modulated microglial activation. He also talks about stroke aftermath, including T cells that remain in the brain and the redistribution of function during recovery.

    • 1 hr 17 min
    Ep. 41: “Autoimmunity and Cancer Immunotherapy” Featuring Dr. Vijay Kuchroo

    Ep. 41: “Autoimmunity and Cancer Immunotherapy” Featuring Dr. Vijay Kuchroo

    Dr. Vijay Kuchroo is the Samuel L. Wasserstrom Professor of Neurology at Harvard Medical School. His major research interests include the role of co-stimulation in autoimmune diseases, as well as cell surface molecules and regulatory factors that regulate the induction of T cell tolerance and dysfunction. He talks about the conditions necessary to differentiate Th17 cells and their role in autoimmunity. He also discusses his group's discovery of Tim-3, an inhibitor receptor on T cells which is now being exploited for cancer immunotherapy.

    • 1 hr 17 min
    Ep. 40: “Bacterial Pathogens” Featuring Drs. Kristin Patrick and Robert Watson

    Ep. 40: “Bacterial Pathogens” Featuring Drs. Kristin Patrick and Robert Watson

    Dr. Kristin Patrick is an Assistant Professor and Dr. Robert Watson is an Associate Professor at Texas A&M University. Their joint lab investigates innate immune regulation during bacterial infection. They talk about gasdermin D and cell death in tuberculosis, and how running a lab together helps them prioritize mentorship.

    • 1 hr 7 min
    Ep. 39: “Extracellular Nucleotides” Featuring Dr. Henrique Borges da Silva

    Ep. 39: “Extracellular Nucleotides” Featuring Dr. Henrique Borges da Silva

    Dr. Henrique Borges da Silva is an Assistant Professor at the Mayo Clinic in Arizona. His main research focus is determining how extracellular nucleotides affect transcriptional, metabolic, and functional mechanisms of CD8+ T cells in response to viral infections and cancer. He talks about where extracellular ATP comes from, and how there could be a link between ATP and ADP immunological signaling and the powers of caffeine.

    • 1 hr 13 min
    Ep. 38: “The Urinary Bladder and Placenta” Featuring Dr. Indira Mysorekar

    Ep. 38: “The Urinary Bladder and Placenta” Featuring Dr. Indira Mysorekar

    Dr. Indira Mysorekar is a Professor of Medicine and Chief of Basic and Translational Research at Baylor College of Medicine. Her lab studies host–microbial interactions in the urinary bladder and the placenta. She discusses the role of the microbiome and the aging immune landscape in recurrent urinary tract infections. She also talks about her research on Zika and SARS-CoV-2 in the placenta.

    • 1 hr 2 min
    Ep. 37: “Co-Evolution of the Human Microbiome” Featuring Drs. Ruth Ley and Sara Clasen

    Ep. 37: “Co-Evolution of the Human Microbiome” Featuring Drs. Ruth Ley and Sara Clasen

    Dr. Ruth Ley is Managing Director of the Max Planck Institute for Biology Tübingen and Director of the Department of Microbiome Science. Dr. Sara Clasen is a postdoctoral fellow in the same lab. Together, they're interested in the co-evolution of humans with their microbiomes. They use basic science to investigate the evolutionary history of gut microbes, how they have adapted to life inside humans, and how they affect human biology and health. More recently, they published a pre-print on the silent recognition of flagellins from human gut commensal bacteria by TLR5.

    • 1 hr 24 min

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