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Full Transcript with references and show notes (https://www.coreimpodcast.com/2019/11/13/5-pearls-on-heparin-induced-thrombocytopenia/)
4:30 What is the daily risk of thrombosis if HIT Is left untreated?
5:40 What happens during platelet activation?
07:11 How long does it take for patients to develop for IgG antibodies to Heparin to form?
09:52 Is HIT common?
10:28 Who is at higher risk for HIT?
11:48 Why does low molecular weight heparin have a lower risk for HIT than unfractionated heparin?
15:30 Approach to thrombocytopenia
17:44 How do medications cause thrombocytopenia?
18:38 With medications, what is the time course between medication initiation and thrombocytopenia?
22:20 What is the sensitivity and specificity of anti-PF4 antibody?
23:58 How does the serotonin-release assay (SRA) work?
29:10 What type of anticoagulant do you choose for treating HIT?
31:58 Why is it important to not use warfarin in patients with platelet counts