Inka Land Podcast Inka Land, MSc

Today, my guest is Dr. Matt Kaeberlein, a CEO of Optispan, anti-aging researcher, Professor at the University of Washington, and founding Director of the University of Washington Healthy Aging and Longevity Research Institute. Dr Kaeberlein is the author of over 250 published scientific research articles on aging, healthspan, and longevity of people and companion animals. Dr. Kaeberlein is a Fellow of the American Association for the Advancement of Science, the American Aging Association, and the Gerontological Society of America. He has received numerous prestigious awards from organizations such as the Alzheimer’s Association and the National Institutes of Health. He has co-founded two companies, Ora Biomedical, Inc., a leading longevity drug discovery biotech, and Optispan, Inc., a healthcare technology company focused on developing innovative tools for 21st-century medicine. He is also the Co-Founder of the Dog Aging Project and Dog Aging Institute.

In this episode, Dr Kaeberlein explains the science and practice of nutrition and longevity. We cover animal and human research on nutrition and anti aging. We discuss calorie restriction, intermittent fasting, time-restricted eating, keto diet (ketogenic diet), protein, Mediterranean diet, and the carnivore diet. We also discuss mechanisms of aging and the most convincing human evidence for nutrition and longevity. Finally, Dr Kaeberlein gives tips and tools for everyday anti aging. We also discuss anti aging in dogs (Dog Aging Project).

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DR MATT KAEBERLEIN LINKS

Website: https://www.optispan.life/
YouTube: https://www.youtube.com/@optispan
X: https://x.com/mkaeberlein
Dog Aging Project: https://dogagingproject.org/

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DISCLAIMER
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TIMESTAMPS

00:00 Intro
00:00:25 Anti Aging Trends
00:04:00 Anti aging, longevity, and healthspan
00:11:50 Healthspan and Biology of Aging
00:13:27 Healthspan and Biology of Aging
00:14:35 Health in Organs
00:15:50 NAD, Health Decline, and Optimal Age for Anti aging
00:17:40 Reversing Aging Damage
00:19:20 Anti Aging Nutrition Research
00:21:10 Caloric Restriction, Calorie Restriction, and Protein Restriction
00:26:00 Risks of Extrapolating and Inflammation
00:28:30 Caloric Restriction, Reproduction and Hormonal Health
00:32:00 Can Ketogenic Diet Increase Lifespan
00:32:50 Genes, Keto diet and Health Benefits
00:35:20 Tool: Blood Test, Labs, DEXA, Vo2max, etc
00:37:15 Biological Age Tests
00:38:20 Human Nutritional Strategies for Anti Aging (Anti Aging diet)
00:39:00 Non-Diet Factors
00:39:40 Sugar, Protein, Continuous Glucose Monitoring, Processed Foods
00:41:20 Mediterranean Diet, MIND Diet, Alzheimer’s Disease
00:42:45 Alcohol
00:43:21 Extreme Diet and Carnivore Diet
00:44:45 Inflammation, Food Intolerance, Immunity, Allergy and Aging
00:50:00 Biological Mechanisms of Aging
00:53:00 IGF-1, mTOR, and cancer
00:54:40 mTOR and Rapamycin, FGF21
00:58:30 Dr. Matt Kaeberlein Longevity Protocol
01:04:00 Anti Aging in Dogs: Dog Aging Project

In this episode, my guest is Cynthia Thurlow, a nurse practitioner and the author of the best-selling book Intermittent Fasting Transformation. Her TEDx talk on Intermittent Fasting currently has over 14 million views. With over 20 years of experience in health and wellness, Cynthia is a globally recognized expert in intermittent fasting and women’s health. Her mission is to educate women on the benefits of intermittent fasting and overall holistic health and wellness and help all women live their most optimal lives.

In this episode, Cynthia explains the practical aspects of Intermittent Fasting. We cover fasting for different life stages. We discuss the wide-ranging benefits of intermittent fasting, including ketosis, autophagy, insulin sensitivity, brain health, and lowering of inflammation. We also discuss supplements for fasting, fasting protocols, salt, and electrolytes. We also cover warnings for fasting and who should not fast. Finally, Cynthia gives practical tips and tools for successful and safe fasting at all ages.



Podcast on iTunes and Spotify
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iTunes: https://podcasts.apple.com/ee/podcast/inka-land-podcast/id1654391974


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Cynthia Thurlow
TEDx talk: https://www.youtube.com/watch?app=desktop&v=A6Dkt7zyImk
Website: https://cynthiathurlow.com/
Instagram: https://www.instagram.com/cynthia_thurlow_/
YouTube: https://www.youtube.com/cynthiathurlow
X: https://twitter.com/_CynthiaThurlow

Research
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9108547/

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Watch on YouTube: https://www.youtube.com/watch?v=htmbcH1ux_s

In this episode, my guest is Dr. Elena Seranova, a research scientist and the CEO of the anti-aging company NMN Bio. Her research on neuronal aging and anti-aging has been published in various high-quality, peer-reviewed journals, including Cell Reports and the Journal of Molecular Biology. She's on a mission to transform how we approach and optimize human health. Her main areas of research and interest are NAD+ metabolism, autophagy, health span optimization, stem cell biology, and insulin sensitivity.

In this episode, Dr. Seranova explains the practical aspects of the NAD molecule and its role in youthfulness, especially the youthfulness of the brain. We discuss NAD's role in mental energy levels and fatigue. We cover how natural NAD decline after age 25 can lead to fatigue, brain fog, and aging. We also discuss her research on counteracting brain oxidative stress with NAD-boosting supplements and amino acids. Finally, Dr. Seranova gives tips and tools for NMN supplements, brain nutrients, and brain health in general – especially regarding maintaining mental energy levels.



Dr. Elena Seranova:
Instagram:   / dr_eseranova  
X:   / eseranova  
LinkedIn:   / publications  

NMN Bio:
Website: https://nmnbio.co.uk/
Instagram NMN Bio:   / nmnbio  
Facebook:   / nmnbio18  

Publications:
https://www.sciencedirect.com/science...https://www.sciencedirect.com/science...https://www.sciencedirect.com/science...https://www.tandfonline.com/doi/full/...

Disclaimer:
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https://youtu.be/AUqNF8YCxHE?feature=shared



In this episode, my guest is Dr. James DiNicolantonio, who holds a Doctor of Pharmacy degree and is a distinguished cardiovascular research scientist. His research contributions include coauthoring more than 300 peer-reviewed scientific articles, demonstrating his extensive influence in the field of medicine. Dr. DiNicolantonio serves as an associate editor for the British Medical Journal's Open Heart and is a valued member of the editorial advisory boards for various prestigious medical journals. In addition to his contributions to scientific literature, he has authored nine best-selling health books, including "The Salt Fix," "Superfuel," "The Longevity Solution," "The Immunity Fix," "The Mineral Fix," "WIN," "The Obesity Fix," "The Collagen Cure," and "The Blood Sugar Fix." Over 2.5 million people follow his health and science insights on Instagram.

In this episode, Dr. DiNicholantonio explains why most people might be salt (sodium) deficient. We cover the background of government recommendations and how these are challenged by the most recent research evidence. We also discuss the link of low sodium to insulin resistance, sugar addiction, high blood pressure, headaches, migraines, muscle cramps, fatigue, and other modern-day symptoms. We cover electrolytes, electrolyte balance, and best sources. Finally, Dr. DiNicholantonio shares his own protocols for optimizing the intake of salt, sodium, and electrolytes.


Dr. James DiNicolantonio
Website: https://www.drjamesdinic.com/
Instagram:   / drjamesdinic  
YouTube:    / @dr.jamesdinicolantonio2215  
X:   / drjamesdinic  

Books
https://www.drjamesdinic.com/

Disclaimer
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Dr. Gil Carvalho is a physician, research scientist, science communicator, speaker and writer. He is a medical doctor with PhD in Biology and has published peer-reviewed medical research in genetics, molecular biology, nutrition, behavior, aging, and neuroscience.



Nutrition research aims to be unbiased, but still leaves most people confused. In this interview, we fact-check nutritional claims and shed light on the latest nutrition research, diets, and intermittent fasting studies.

You'll get the answer to: What's better intermittent fasting or calorie restriction? Should you go carnivore or plant-based? Is The Game Changers documentary scientifically accurate? Why there's so much controversy in nutrition?



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Dr Gil Carvalho (Nutrition Made Simple)
YouTube: https://www.youtube.com/@NutritionMad...
Facebook: https://www.facebook.com/DrGilCarvalho/
Twitter: https://twitter.com/NutritionMadeS3

Dom D'Agostino is a renowned researcher and professor in neuroscience, physiology, and metabolic health. He has significantly contributed to studying the ketogenic diet, oxygen toxicity, hyperbaric medicine, and nutritional ketosis. His work has explored the impact of ketones and ketogenic diets can improve functioning and health in different conditions, insulin sensitivity, inflammation, and overall metabolic health. His work has significantly impacted the understanding and application of metabolic therapies, especially the ketogenic diet and exogenous ketones, in improving health and performance.


In this interview, we cover how exogenous ketones work inside your body, how you can use them for brain health, muscle perseverance, reversing dementia, and as a nootropic and mental health benefits.

We cover how you can harness the benefits of ketones without going to the ketogenic diet. Dom also reviews the best ketone products on the market.

Inka Land (MSc neuropsychology) shares tools and habits for mental well-being, brain health, and a balanced lifestyle. She's a TEDx speaker and co-author of educational books on health.

https://www.youtube.com/@iaminkaland