On The Pen: The Weekly Dose Dave Knapp Man On The Mounjaro

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1.7 mg of Wegovy is no longer in shortage:
Semaglutide: FDA website updated to show 1.7 mg of Wegovy is no longer in shortage
Link: https://www.accessdata.fda.gov/scripts/drugshortages/dsp_ActiveIngredientDetails.cfm?AI=Semaglutide%20Injection&st=c

GNC introduces special section for GLP-1 users:
GNC will have special section for GLP-1 users that will concentrate on four areas: GI Health, Retaining Lean muscle mass, Bone health, Nutritional support
Link: https://www.gnc.com/learn/newsroom/gnc-semaglutide-support-program.html

Identified upper dose values in tirzepatide high-dose trial
20 mg and 25 mg
Primary Completion in this trial is 12/24/2024 (Merry Christmas) with final completion September 30, 2025 
Link:  https://www.onthepen.com/post/higher-doses-of-zepbound-and-mounjaro-being-tested

US Senator Bernie Sanders investigating the price of Wegovy/Ozempic
Ozempic costs $936 per month, while Wegovy costs $1,350
Ozempic costs $155 in Canada, and cost $59 in Germany. This dramatic difference in cost has led to concerns about the accessibility and affordability of these drugs for American patients.
With the cardiovascular disease indication, millions of additional medicare patients are eligible for taking Wegovy which means billions at the current prices 
Link:  https://www.onthepen.com/post/the-price-of-health-bernie-sanders-investigates-ozempic-and-wegovy
Link: https://www.kff.org/medicare/issue-brief/a-new-use-for-wegovy-opens-the-door-to-medicare-coverage-for-millions-of-people-with-obesity/

Germany is promoting their pharmaceuticals industry:
 tax breaks, and speeding up clinical trials
Eli Lilly is investing 2.3 Billion Euros to build a glp-1 manufacturing plant in Germany:
Link: https://uk.finance.yahoo.com/news/scholz-promises-support-pharma-sector-101833297.html

Lexaria begins phase 1 trial:
Lexaria (stock symbol: LEXX) will test their technology to improve stomach absorption of Rybelsus in phase 1 trial (i.e. wouldn't need large 25/50 mg doses if absorption was better). 
They are also testing under tongue (sublingual) absorption of Rybelsus in another phase 1 trial
Link: https://ir.lexariabioscience.com/news-events/press-releases/detail/246/lexaria-receives-ethics-review-board-approval-to-begin-new

Viking Therapeutics earnings call
Planning to start addition phase 2 trial of injectable VikingTide (VK2735) in Q4 of 2024 that will last 6-9 months (If you remember, the first phase 2 trial was only 13 weeks)
The oral VikingTide (VK2735) phase 1 trial is still investigating higher and higher  doses due to the low side effect profile. They expect results in summer of 2024.


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Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit my website at onthepen.com. You can also connect with me on social media, where I go by @manonthemounjaro (or @manonmounjaro on X). Let's continue this journey together towards a healthier and happier life!

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New obesity medicine company launches, Lilly expands manufacturing capacity with acquisition, and TikTok censors my content.

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New Obesity Medicine Company Launches: https://metsera.com/news
Lilly Acquires Nexus Facility: https://finance.yahoo.com/news/lilly-buy-injectable-drug-plant-175000782.html
TikTok Mounjaro Zepbound Censorship: https://www.bloomberg.com/news/articles/2024-04-22/tiktok-ozempic-influencers-say-new-rules-unfairly-target-them

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Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit my website at onthepen.com. You can also connect with me on social media, where I go by @manonthemounjaro (or @manonmounjaro on X). Let's continue this journey together towards a healthier and happier life!

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Dave Knapp makes the business case for why Eli Lilly won’t simply release the vials - they have to.

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Bloomberg #ReleaseTheVials Feature:
https://www.bloomberg.com/news/articles/2024-04-02/zepbound-shortage-patients-push-eli-lilly-to-release-more-obesity-drug-supply

Yahoo Finanace #ReleaseTheVials Feature VIDEO: https://youtu.be/nQbYa47DF4Q?feature=shared

#mounjaro #zepbound #tirzepatide
Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit my website at onthepen.com. You can also connect with me on social media, where I go by @manonthemounjaro (or @manonmounjaro on X). Let's continue this journey together towards a healthier and happier life!

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This week Dave Knapp covers GLP-1 censorship on TikTok,  the rise of bootleg medication scrutiny, and just how big the GLP-1 market may get in 2024.

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Bloomberg #ReleaseTheVials Feature:
https://www.bloomberg.com/news/articles/2024-04-02/zepbound-shortage-patients-push-eli-lilly-to-release-more-obesity-drug-supply

Yahoo Finanace #ReleaseTheVials Feature VIDEO: https://youtu.be/nQbYa47DF4Q?feature=shared

#mounjaro #zepbound #tirzepatide

Bootleg Meds:
https://www.reuters.com/business/healthcare-pharmaceuticals/more-than-250-websites-selling-fake-weight-loss-drugs-reported-by-anti-2024-04-15/

 Drug Shortage Reporting: https://www.wsj.com/health/healthcare/drug-medication-shortages-us-olympic-amoxicillin-107fa9d8

GLP-1 Sales:
https://www.fiercepharma.com/marketing/glp-1s-track-take-drug-sales-crown-pd-1-inhibitors-2024-analyst


Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit my website at onthepen.com. You can also connect with me on social media, where I go by @manonthemounjaro (or @manonmounjaro on X). Let's continue this journey together towards a healthier and happier life!

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503a vs 503b pharmacies. What is the difference, and why you should care when it comes to compound tirzepatide and semaglutide.

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Bloomberg #ReleaseTheVials Feature:
https://www.bloomberg.com/news/articles/2024-04-02/zepbound-shortage-patients-push-eli-lilly-to-release-more-obesity-drug-supply

Yahoo Finanace #ReleaseTheVials Feature VIDEO: https://youtu.be/nQbYa47DF4Q?feature=shared

#mounjaro #zepbound #tirzepatide

Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit my website at onthepen.com. You can also connect with me on social media, where I go by @manonthemounjaro (or @manonmounjaro on X). Let's continue this journey together towards a healthier and happier life!
Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit my website at onthepen.com. You can also connect with me on social media, where I go by @manonthemounjaro (or @manonmounjaro on X). Let's continue this journey together towards a healthier and happier life!

Send us a Text Message.
Get the whole story at: https://www.onthepen.com

Bloomberg #ReleaseTheVials Feature:
https://www.bloomberg.com/news/articles/2024-04-02/zepbound-shortage-patients-push-eli-lilly-to-release-more-obesity-drug-supply

Yahoo Finanace #ReleaseTheVials Feature VIDEO: https://youtu.be/nQbYa47DF4Q?feature=shared

Yahoo Finance Catalent / Novo Deal Resubmission: https://finance.yahoo.com/news/novo-nordisk-parent-refiles-us-103118874.html

Bloomberg Lilly Germany Plant:
https://www.bloomberg.com/news/articles/2024-04-08/lilly-s-2-5-billion-german-plant-will-boost-obesity-drug-supply



Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit my website at onthepen.com. You can also connect with me on social media, where I go by @manonthemounjaro (or @manonmounjaro on X). Let's continue this journey together towards a healthier and happier life!