20 episodios

A fascinating, informative and digestible podcast highlighting the rich and diverse neuroscience published in the Brain journals.
The episodes will take the format of interviews with article authors and the aim is to produce an informal and enjoyable podcast that appeals to a broad audience including clinicians, researchers, students, neuroscientists, neurologists, neurosurgeons and psychiatrists

The Brain Podcast Joanne Bell

    • Ciencia

A fascinating, informative and digestible podcast highlighting the rich and diverse neuroscience published in the Brain journals.
The episodes will take the format of interviews with article authors and the aim is to produce an informal and enjoyable podcast that appeals to a broad audience including clinicians, researchers, students, neuroscientists, neurologists, neurosurgeons and psychiatrists

    The essential Role of PAK2 in Myelinating the Peripheral Nervous System

    The essential Role of PAK2 in Myelinating the Peripheral Nervous System

    Welcome to the 20th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. 
    This episode features a discussion with the final author Dr Jun Li of the Brain article entitled: PAK2 is necessary for myelination in the peripheral nervous system
    How are peripheral nerve cells myelinated and what proteins are invoved? Is there a difference between PAK1 and PAK2? Listen for this and more in this exciting episode.
    Check out the full article on the Brain website: https://doi.org/10.1093/brain/awad413
    This episode was co-hosted by Andreas Thermistocleous and David Michael,  edited and produced by David and Xin You Tai, co-produced by Antonia Johnston, original music by Ammar Al-Chalabi.

    • 25 min
    How is the gut microbiota related to cognition and hippocampal neurogenesis in Alzheimer's disease?

    How is the gut microbiota related to cognition and hippocampal neurogenesis in Alzheimer's disease?

    Welcome to the 18th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. 
    This episode features a discussion with first author author Dr Stefanie Grabrucker of the Brain article entitled: Microbiota from Alzheimer’s patients induce deficits in cognition and hippocampal neurogenesis
    How does lifestyle and the environment affect cognition in Alzheimer's disease via the gut and what can we do about it? Listen for this and more in this exciting episode.
    Check out the full article on the Brain website: https://doi.org/10.1093/brain/awad303
    This episode was co-hosted by Chaitra Sathyaprakash and Adam Handel,  edited and produced by Chaitra and Xin You Tai, co-produced by Antonia Johnston, original music by Ammar Al-Chalabi.

    • 29 min
    Do noradrenergic alterations in Parkinson’s disease indicate a therapeutic target? A combined PET & neuromelanin MRI study

    Do noradrenergic alterations in Parkinson’s disease indicate a therapeutic target? A combined PET & neuromelanin MRI study

    Welcome to the 17th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. 
    This episode features a discussion with senior author Dr Bénédicte Ballanger of the Brain article entitled: Noradrenergic alterations in Parkinson’s disease: a combined 11C-yohimbine PET/neuromelanin MRI study
    Can this multi-modal study examining the role of Noradrenaline in Parkinson's disease offer insight into important neurotrasmitter pathophysiology and provide the basis for a non-dopamine therapeutic strategy?
    Check out the full article on the Brain website: https://doi.org/10.1093/brain/awad338
    This episode was co-hosted by Andreas Themistocleous and Michael David,  edited and produced by Michael David and Xin You Tai, co-produced by Antonia Johnston, original music by Ammar Al-Chalabi.

    • 22 min
    Altered brain glucose metabolism as a mechanism for delirium?

    Altered brain glucose metabolism as a mechanism for delirium?

    Welcome to the 16th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. 
    We are very excited to feature a January issue Brain article, where we speak with senior author Dr Lasse M Giil entitled:  Impaired glucose utilization in the brain of patients with delirium following hip fracture
    Delirium is a common condition with significant impact on patient outcome. This episode discussed potential intrinsic brain mechanisms that may underly delirium. The team explores the evidence that delirium is more than just a systemic process that extends into the brain but may involve pathophysiological alterations of brain function. Listen to how this may change clinical practice. 
    Check out the full article on the Brain website: https://doi.org/10.1093/brain/awad296
    This episode was co-hosted by Andreas Themistocleous and Michael David,  edited and produced by Michael David and Xin You Tai, co-produced by Antonia Johnston, original music by Ammar Al-Chalabi.

    • 16 min
    Are there differences in the immune response among individuals of Black ethnicity with multiple sclerosis?

    Are there differences in the immune response among individuals of Black ethnicity with multiple sclerosis?

    Welcome to the 15th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. 
    We are very excited to feature our first article from Brain Communications, where we speak with first author Dr Kiel Telesford of the article entitled: Neuron-binding antibody responses are associated with Black ethnicity in multiple sclerosis during natalizumab treatment
    This episode discussed racial differences in antibody response to natalizumab treatment for individuals of black ethnicity with multiple sclerosis. Further, they consider potential mechanisms which may underly differences and the implications on treatment. 
    Check out the full article on the Brain Communications website: https://doi.org/10.1093/braincomms/fcad218
    This episode was co-hosted by Andreas Themistocleous and Debra Ehrlich,  edited and produced by Michael David and Xin You Tai, co-produced by Antonia Johnston, original music by Ammar Al-Chalabi.

    • 19 min
    Exploring a genetic basis for disordered speech and language: FOXP2 mutations and striatal neurons

    Exploring a genetic basis for disordered speech and language: FOXP2 mutations and striatal neurons

    Welcome to the 14th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. 
    In this episode we speak with Fu-Chin Liu, senior author of the article entitled: Speech- and language-linked FOXP2 mutation targets protein motors in striatal neurons. 
    This article explores a potential genetic basis for disordered speech by a mutation in the transcription factor FOXP2. This was discovered in KE family members with speech disturbances was a landmark example of the genetic control of vocal communication in humans. The author and colleagues examine an animal model of the KE family FOXP2R553H mutation to explore cellular pathomechanisms involving intracellular dynein-dynactin ‘protein motors’ in the striatum.
    Check out the full article on the Brain website: https://doi.org/10.1093/brain/awad090
    We also hear from our new podcast host, Dr Chaitra Sathyaprakash, who is a post-doctoral fellow at National Institute of Neuroscience, Kodaira, Tokyo, Japan- welcome to the team!
    This episode was co-hosted by Adam Handel and Chaitra Sathyaprakash,  edited and produced by Xin You Tai, co-produced by Antonia Johnston, original music by Ammar Al-Chalabi.

    • 20 min

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