The Doctor's Farmacy with Mark Hyman, M.D‪.‬ Dr. Hyman+

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I'm turning 65 this year and feel younger, fitter, and more vibrant than ever. Thanks to my longevity routine, I’ve been able to reverse my biological age by 20 years, plus an additional year in the past five months alone!
As I grow older, I’ve learned that what’s possible when we nourish our bodies, get regular exercise, quality sleep, and manage our stress – we can effectively turn back our biological clock. Add a supplement stack and hormetic stressors to activate our longevity switches, and you’re setting a solid foundation for lasting health. So, how does someone in their 60s build muscle and sport abs that could rival their younger selves? 
In today’s Health Bites episode, I’m sharing the exclusive details behind my longevity routine that anyone can try on their journey towards a healthier, longer life. Whether you want to sharpen your mind, enhance your physique, or simply feel younger, this episode is for you. Remember, it’s not just about adding years to your life, but life to your years. 
In this episode, I discuss:

My morning routine for longevity (2:46)

How I get the benefits of exercise in minimal time (3:23)

A look at the ingredients in my Healthy Aging Shake (5:54)

What I eat in a day (lunch and dinner) to support longevity (11:46)

The role of dietary protein for longevity and how much to eat every day(15:03)

How to activate your longevity switches using the power of hormesis (23:00)

Top tips for active relaxation and rejuvenation (28:51)

My nightly routine for sleep optimization (30:01)

The supplement I take for optimal health and longevity (32:01)

Why lab testing is crucial for longevity and optimal health (33:31)

Personal experience and experimentation with advanced longevity therapeutics (36:55)


This episode is brought to you by Timeline Nutrition and Cymbiotika.
Support essential mitochondrial health and save 10% on Mitopure. Visit TimelineNutrition.com/Drhyman and use code DRHYMAN10.
Upgrade your supplement routine with Cymbiotika. Get 20% off with free shipping on all orders. Head to Cymbiotika.com and use code HYMAN.

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Like most things in life, when it comes to optimizing metabolic health, a nuanced perspective can help. Rather than viewing it as a black-and-white issue, we can take into consideration the big-picture social context we’re facing that encourages ultra-processed foods, obesity, and lifelong medication as well as the micro-level of what people are experiencing as individuals and understanding how to help them when all else fails. Today I’m thrilled to sit down with Dr. Tyna Moore and Calley Means for a grounded discussion that explores both sides of the spectrum, and everything in between. 
In this episode, we discuss:

The controversial discussion of GLP-1 agonists like Ozempic, weighing the pros and cons of these new drugs in treating obesity and metabolic crises (3:34)

Challenging the notion of treating obesity with drugs like Ozempic (10:35)

An unsettling revelation about the push for using Ozempic in children (12:04)

Digging deeper into GLP-1 research and some of the benefits (32:51)

Why are children being born metabolically challenged? (41:11)

Dr. Moore’s approach to using peptides with her patients and for her own crippling pain, and what they’ve seen (45:19)

How our current healthcare system lacks policies and support for behavior change (1:27)


While there are always differing views, we know for sure that our food and drug policies aren’t serving the best interests of creating sustainable, empowered health for the masses. I hope you’ll tune in to hear more from this comprehensive and lively discussion. 

This episode is brought to you by Rupa Health, Pendulum, ARMRA Colostrum, and One Skin.
Streamline your lab orders with Rupa Health. Access more than 3,000 specialty lab tests and register for a FREE live demo at RupaHealth.com.
Pendulum is offering listeners 20% off their first month’s subscription of Akkermansia for gut health. Visit PendulumLife.com and use code HYMAN.
Save 15% on your first order of ARMRA Colostrum and unlock the power of 400+ functional nutrients. Just visit TryARMRA.com/Mark or use code MARK.
Unlock your healthiest skin yet. Try OneSkin with 15% off your first purchase using code HYMAN15 at OneSkin.co today.

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Gas, bloating, constipation, diarrhea, urgency, and painful cramping—these are just some of the many difficult symptoms that come along with inflammatory bowel disease, also known as IBD. This disorder is an umbrella term for a variety of symptoms and diagnoses, including ulcerative colitis and Crohn’s disease, and it impacts millions of Americans each day.
In this episode, Dr. Hyman speaks with Dr. George Papanicolaou, Dr. Miguel Reguiro, and Dr. Shilpa Ravella about the Functional Medicine approach to reducing symptoms of IBD that extend beyond medications and surgery.
This episode is brought to you by Rupa Health and LMNT.
Streamline your lab orders with Rupa Health. Access more than 3,000 specialty lab tests and register for a FREE live demo at RupaHealth.com.
LMNT is giving listeners a FREE eight-count sample pack of their vital electrolyte drink mix with any purchase. Just visit DrinkLMNT.com/Hyman today.

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In the health space, we hear the term ultra-processed foods thrown around often for its clear link to chronic diseases such as depression, Alzheimer’s, and diabesity. But what exactly does “ultra-processed” mean? How can you tell if a food is ultra-processed?

In today’s Health Bites episode, we will learn exactly what ultra-processed foods are, how to identify them, their impact on human health, and the global economy. We’ll also discuss tips and tricks for how to read food labels to better navigate the grocery store, and the innovations happening in Washington to develop label laws that helps protect the consumer.

In this episode, I discuss:

Definition, examples, and deceptive health claims of ultra-processed food (2:06) 

Health risks and impacts of ultra-processed food (7:30) 

Case study: impact of an ultra-processed diet on twin girls (10:00) 

History and rise of processed food (12:09) 

Difference between ultra-processed and minimally processed foods (17:45) 

Impact of food packaging and additives on health (24:01) 

Economic and societal consequences of chronic diseases caused by poor diet (28:04) 

Identifying ultra-processed foods and understanding food labeling (35:00) 

Avoiding ultra-processed foods and using food scoring systems (40:50) 


This episode is brought to you by Rupa Health, Essentia, and Cymbiotika.

Streamline your lab orders with Rupa Health. Access more than 3,000 specialty lab tests and register for a FREE live demo at RupaHealth.com.

Receive an extra $100 off your mattress purchase! Go to myessentia.com/drmarkhyman and use code HYMAN at checkout to get this great deal.

Upgrade your supplement routing with Cymbiotika. Get 20% off with free shipping on all orders. Head to Cymbiotika.com and use code HYMAN.

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The prevalence of autism has risen a shocking 400% in the last twenty years. Increased awareness and diagnosis are one piece, but there are also so many other factors to consider. The hopeful news is that we’re seeing a shift paradigm in how we view and treat autism, with some truly amazing improvements possible. I’m thrilled to welcome Dr. Suzanna Goh, a board-certified pediatric behavioral neurologist, behavioral analyst, neuroscience researcher, Rhodes scholar, and author.

In this episode, we discuss:


Shaking things up around the autism paradigm (1:57)

The connection between the brain and mitochondria (6:04)

Can autism be reversed? (7:00)

The biggest mistake made in autism (10:10)

What creates the inflammatory fire in the autistic brain? (15:20)

The role of diet in autism treatment (19:17)

Functional tests for assessing brain function and how to best support kids with autism (26:30)

Mitochondrial dysfunction and autism (28:30)

"Magnificent Minds" - A book on autism by Dr. Suzanne Goh (34:57)


Using a whole-child approach and investigating the intricate connections between metabolism, mitochondrial function, and nutrition we can better understand what types of support autistic children need most. I hope you’ll listen in to learn more. 

This episode is brought to you by Rupa Health, AG1, and Essentia.

Streamline your lab orders with Rupa Health. Access more than 3,000 specialty lab tests and register for a FREE live demo at RupaHealth.com.

Get your daily serving of vitamins, minerals, adaptogens, and more with AG1. Head to DrinkAG1.com/Hyman and get a years worth of D3 and 5 Travel Packs for FREE with your first order.

Receive an extra $100 off your mattress purchase! Go to myessentia.com/drmarkhyman to get this great deal.

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Our global mental health crisis is growing at an exponential rate, with over half a billion people suffering from depression and anxiety; it’s time we rethink our understanding of the underlying root causes of mental health challenges.

From treating thousands of patients, I’ve learned that depression is not in your head. It’s in your body. More specifically, your gut. When your gut is unhealthy and inflamed, your brain is unhealthy and inflamed. In Functional Medicine, we know that the gut and the brain are intimately connected and that the health of one directly influences the health of the other. 

In today’s Health Bites episode, we’re diving into the gut-brain connection and sharing Functional Medicine tools to support your gut health and, as a result, your mood and mental health. 

In this episode, I discuss:

Our global mental health crisis (2:45)

The gut-brain connection (4:18)

The story of Marks's broken brain (5:15)

Features of the gut-brain axis (8:57)

Gut hormones that send signals to your brain (10:06)

Role of the gut microbiota in mood and mental health (12:24)

How stress negatively impacts our gut microbiome (20:14)

The link between leaky gut and poor mental health (21:41)

The Functional Medicine approach to fixing the gut (25:56)

The 5R Program for fixing your gut health (30:09)


This episode is brought to you by AG1 and Rupa Health.

Get your daily serving of vitamins, minerals, adaptogens, and more with AG1. Head to DrinkAG1.com/Hyman and get 10 FREE travel packs + FREE Welcome Kit with your first order.

Streamline your lab orders with Rupa Health. Access more than 3,000 specialty lab tests and register for a FREE live demo at RupaHealth.com.