Episode two is designated to personal insight from two senior scientists from our department, who dedicated their remarkably successful careers to lung injury. Michael Quintel and Luciano Gattinoni are both regarded outstanding ARDS and ECMO experts, who helped to shape the lung injury field over the past decades, Michael Quintel as the chair of Intensive Care Medicine and later the whole Anaesthesia department at the Universitätsmedizin Göttingen in Germany, and Luciano Gattinoni as the Chief of the Hospital Department of Anaesthesia, Intensive Care and Emergency and Medical Director in Milan, Italy. They both united here in Göttingen after stepping down from their respective clinical leadership positions to establish a lung injury research group, which is thriving and quite successful. The SARS-Cov2/COVID-19 pandemic has turned the view of many clinical experts towards lung pathophysiology, and the expertise of our two opinion leaders. This moderated interview will be continued.