The Top Line Fierce Life Sciences

The Fierce Pharma Marketing team publishes a special report each year on the top pharmaceutical drug ad spenders. This year’s report, which includes numbers for 2023, was published on Monday.  

AbbVie was the standout in this edition, having spent heavily on ads for Skyrizi and Rinvoq. Overall spending on the top 10 ads also experienced a sizable increase compared to the previous year. 

In this week’s episode of “The Top Line,” Fierce Pharma Marketing Senior Editor Ben Adams and Deputy Editor Andrea Park discuss the report, providing key insights and takeaways.  

To learn more about the topics in this episode:  

The top 10 pharma drug ad spenders for 2023
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The Fierce Biotech team published a four-part series this week exploring cell therapy, a modality that has faced clinical challenges, manufacturing constraints and multiple practice-changing events.  

In today’s episode, Fierce’s Annalee Armstrong and Gabrielle Masson discuss the series of special reports and key insights from their interviews with multiple experts.  

To learn more about the topics in this episode: 


Cell therapy reckoning: How a 'remarkable resolution of lupus' carried CAR-T from cancer to immunology
Cell therapy reckoning: Pivot to autoimmune leaves unmet need in oncology
Biotech faces a reckoning: 'We've lost our luster in cell therapies'
Fulfilling the promise of cell & gene therapies through manufacturing (Part I)
From cell collection to commercial contracting: Advancements in cell & gene therapy manufacturing (Part II)
Automation, decentralization and the future of CAR-Ts: Advancements in cell & gene therapy manufacturing (Part III)

 
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This week’s episode of “The Top Line,” is the final part of a three-part series diving into the latest advancements in cell and gene therapy manufacturing. 

In this episode, Fierce Pharma’s Fraiser Kansteiner is joined by Bruce Levine, Ph.D., who is the co-inventor of Kymriah and the Barbara and Edward Netter Professor in Cancer Gene Therapy at the University of Pennsylvania. He’s also joined by executives from CGT technology provider ScaleReady and regenerative cell therapy developer CellProthera.  

They dive into novel production approaches discussed earlier in this series, with a special focus on CAR-T therapies.  

To learn more about the topics in this episode:


CAR-T hype faces infrastructure reality check
CAR-T boxed warnings: What comes next?
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Agilent execs discuss the regulatory challenges and technological opportunities of digital pathology and companion diagnostics.

What is the transformative potential of digital health technologies in advancing health equity? Rabin Martin, a global health consulting firm, explores those possibilities.

This week’s episode of “The Top Line” is the second part of a three-part series exploring the latest advancements in cell and gene therapy manufacturing.

In this episode, Fierce Pharma’s Fraiser Kansteiner interviews Delara Motlagh, head of cell therapy at Catalent; Becky Butler Cap, senior vice president of biotherapies at Vitalant; and Kevin Kyle, CEO of Germfree.

The conversation covers cell collection, the critical first step in advanced therapy manufacturing. They also discuss the importance of locking in process decisions early and how to effectively scale projects from the lab to the clinic and eventually to the market. Additionally, they talk about Germfree’s recent asset acquisition from Orgenesis, which will allow the company to expand its mission of decentralized manufacturing.

To learn more about the topics in this episode:


Fulfilling the promise of cell & gene therapies through manufacturing (Part I)
With new partnership, Galapagos takes decentralized CAR-T manufacturing quest nationwide
Catalent opens cell therapy production site at Belgian 'center of excellence'
After recent troubles, Catalent expands its biologics services platform

 
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