99 episodes

The radio show/podcast educates the public on genetic and public health topics through event coverage, news stories, book/movie reviews, and interviews. Guest include genetic counselors, researchers, patient advocates and professors in the field of genetics.

DNA Today: A Genetics Podcas‪t‬ Kira Dineen

    • Science

The radio show/podcast educates the public on genetic and public health topics through event coverage, news stories, book/movie reviews, and interviews. Guest include genetic counselors, researchers, patient advocates and professors in the field of genetics.

    #145 Greenwood Genetic Center on Epigenetics

    #145 Greenwood Genetic Center on Epigenetics

    Greenwood Genetics Center’s Ray Louie and Kellie Walden join the show to discuss epigenetics.

    Dr. Ray Louie is an Assistant Director in Greenwood’s Molecular Diagnostic Laboratory. His background is in large scale genetic screening in model organisms and in solid tumor genetics and radiobiology. Dr. Louie is interested in the diagnosis of Mendelian disorders and in the identification of novel genes involved in neurodevelopmental delay and hydrops fetalis.

    Kellie Walden is Greenwood’s Director of Diagnostic Development and a genetic counselor by training. She oversees areas of growth for the labs including new test offerings and industry contracts. She also continues to be involved in marketing activities for the Diagnostic Lab. Kellie is a member of the National Society of Genetic Counselors.

    EpiSign is the first clinical assay validated to detect unique epigenetic signatures and methylation abnormalities for recognized genetic conditions. Right now, EpiSign tests for over 40 conditions that have signatures. Version 3 will be launching in the spring with even more conditions! This test was developed by London Health Sciences Centre in Ontario, and our lab at the Greenwood Genetic Center performs the bench work and the data is analyzed by the team in Canada. The National Human Genome Research Institute named EpiSign one of the 10 most significant advances in genomic medicine in 2019!

    On This Episode We Discuss:

    Defining epigenetics
    Epigenetic disorders (Prader–Willi, Angelman, Beckwith-Wiedemann syndrome)
    Testing for epigenetic conditions through EpiSign
    Indications to order epigenetic testing
    Variant of Uncertain Significance (VUS) clarification with EpiSign
    Current research on epigenetic conditions
    New versions of EpiSign
    Calculating biological age with epigenetics
    Learn more about Greenwood Genetic Center’s EpiSign here. You can also check out their incredibly popular genetic counseling visual aids.

    Enter our giveaway on Instagram, Twitter, Facebook, and LinkedIn to win a pair of bluetooth, noise canceling headphones from Greenwood. Giveaway ends on April 11th.

    Ray and Kellie showcased how complex pediatric genetics can be, so it’s understandable that people are often confused about the role genetics play in health conditions. The genetic counselors over at Advanced Tele-Genetic Counseling (ATGC) specialize in areas of genetics like pediatrics. So if you find yourself having questions about your own genetics, or want to know more about adding the expertise of AT-GC’s certified genetic counselors to help support your own practice, reach at AT-GC.com. You can also hear Elizabeth Turner on Episode #143 where she shares more about telehealth and what ATGC has to offer.

    Stay tuned for the next episode of DNA Today on April 16th, which explores whole exome sequencing with QuantGene’s Jo Bhakdi! New episodes are released on the first and third Friday of the month. In the meantime, you can binge over 140 other episodes on Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “DNA Today”. Brand new in 2021, episodes are now also recorded with video which you can watch on our YouTube channel.

    See what else we are up to on Twitter, Instagram, Facebook, YouTube and our website, DNApodcast.com. Questions/inquiries can be sent to info@DNApodcast.com.

    • 28 min
    #144 Orion Buske on Genomic Digital Tools

    #144 Orion Buske on Genomic Digital Tools

    This episode of DNA Today continues our mini series about telehealth in genetics. Last episode we heard from the founder of Advanced Tele-Genetic Counseling, Elizabeth Turner, who shared her expertise in telehealth. Her company provides a scalable telehealth platform for genetic counseling services, where genetic counselors can help patients navigate through areas of genetics like genetic testing, and ultimately understand their own genetics. So if you want to know more about adding the expertise of AT-GC’s certified genetic counselors to help support your own practice, reach out through their website at at-gc.com, again that’s at-gc.com.

    In part two of our telehealth series, Orion Buske, PhD, joins host Kira Dineen to discuss genomic digital tools. Dr. Buske strives to empower patients, doctors, and researchers through new tools and technologies. He holds a PhD in Computer Science from the University of Toronto, where he specialized in algorithms for genome analysis and rare disease patient matchmaking. At various times, he led the technical developments of: PhenomeCentral, the Matchmaker Exchange, PatientKind, and RareConnect.

    On This Episode We Discuss:
    Inspiration to start PhenoTips
    Genomic Health Records
    Benefits of Digital Tools for patients and providers
    Digital vs paper pedigrees
    Auto pedigree builder
    Speeding up the diagnostic odyssey
    Future of genomic digital tools

    Hear more from PhenoTips and our host Kira Dineen through the PhenoTips Speaker Series. This a monthly live webinar where Kira interviews genetic experts about topics and skills specifically for genetic healthcare providers. All previous installments have been recorded and are available on demand here.

    Stay tuned for the next new episode of DNA Today on April 2nd! We will be joined by Greenwood Genetic Center to discuss epigenetics including their unique genetic test, EpiSign. Don’t miss their bluetooth, noise cancelling headphones giveaway on our Instagram, Twitter, Facebook, and LinkedIn.

    New episodes are released on the first and third Friday of the month (with some bonus episodes like this one!). In the meantime, you can binge over 140 other episodes on Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “DNA Today”. Brand new in 2021, episodes are now also recorded with video which you can watch on our YouTube channel.

    See what else we are up to on Twitter, Instagram, Facebook, YouTube and our website, DNApodcast.com. Questions/inquiries can be sent to info@DNApodcast.com.

    #143 Elizabeth Turner on Telehealth Genetic Counseling

    #143 Elizabeth Turner on Telehealth Genetic Counseling

    To kick off our mini series in telehealth genetics fellow genetic counselor, Elizabeth Turner joins our host Kira Dineen. Elizabeth is the cofounder and Chief Executive Officer of Advanced Tele-Genetic Counseling (AT-GC). Elizabeth’s team, one of the first tele-genetic companies to enter the industry, provides comprehensive genetic counseling services via telemedicine. Elizabeth has practiced in the areas of oncology, pediatrics, reproductive health, and general genetics, and holds a current certification from the American Board of Genetic Counseling.

    On This Episode We Discuss:
    Motivation to start AT-GC
    Initial hurdles to telehealth
    COVID-19’s impact on telehealth
    Telehealth affecting disparities in genetics
    Languages AT-GC offer for sessions
    Specialties in genetic counseling AT-GC provides
    Scenarios where telehealth is preferable to in person
    Coordinating samples for genetic testing
    Genetic counseling telehealth internships and rotations
    Future of telehealth

    Learn more about Elizabeth Turner and her company, Advanced Tele-Genetic Counseling (AT-GC) on their website.

    Did you know most people are visual learners? That’s why visual aids are critical during genetic counseling appointments. As we explore in this show, genetic concepts can be really complex to understand, which is why the Greenwood Genetic Center created genetic counseling aids. And now their 7th edition is available, including an app for iPads. In telehealth appointments it can be incredibly helpful to share your screen with these visual aids from Greenwood, so download this vital tool for your daily practice here!

    We receive a lot of emails from listeners interested in genetic careers and we love connecting and providing resources. One of those is Keck Graduate Institute’s genetics programs in Southern California. KGI offers a master’s degree in genetic counseling and a first-of-its-kind graduate program in genomic data analytics. Both programs are two-year master’s program. The genomic data analytics program gives students the opportunity to work side-by-side with applied life scientists and future genetic counselors while gaining hands-on experience with the technologies and information that are revolutionizing the future of medicine. Learn more about KGI’s programs by visiting kgi.edu/dnatoday.

    Stay tuned for the next new episode of DNA Today dropping next Friday (March 26th)! This will continues our mini series in telehealth genetics. The CEO of PhenoTips, Dr. Orion Buske, will be sharing his expertise on digital tools in genetic counseling.

    New episodes are released on the first and third Friday of the month. In the meantime, you can binge over 140 other episodes on Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “DNA Today”. Brand new in 2021, episodes are now also recorded with video so you can watch the show on our YouTube channel.

    See what else we are up to on Twitter, Instagram, Facebook, YouTube and our website, DNApodcast.com. Questions/inquiries can be sent to info@DNApodcast.com.

    • 28 min
    #142 Barbara Fortini on Genomic Data Analytics

    #142 Barbara Fortini on Genomic Data Analytics

    Dr. Barbara Fortini joins our host Kira Dineen, to discuss the growing career opportunities in Genomic Data Analytics. She is the Program Director for the Master of Science in Human Genetics and Genomic Data Analytics program at the Keck Graduate Institute. She also teaches their genetic counseling students.

    Her research interests focus on colorectal cancer, the third most common cancer in the US. Genome-wide association studies have now identified dozens of common genomic variants linked to small increases in colorectal cancer risk. Her research group seeks to identify the functional variants responsible for the increased cancer risk at GWAS-identified loci and to understand the role of these variants in cancer etiology. Previous work has shown that many functional variants lie in gene enhancer elements, leading to allele-specific gene expression of both known cancer-associated genes and novel genes. By comprehensively characterizing risk loci, her team hopes to identify additional novel genes involved in colorectal cancer and better understand the role of enhancers in gene expression in healthy and cancer cells.

    On This Episode We Discuss:

    Career paths in genetics outside of genetic counseling
    Defining big data in a genetic context
    Area of research impacted by data analytics
    Career opportunities in the healthcare industry
    Challenges in labs and pharma companies addressed by genomic data analytics
    Genome wide association studies (GWAS)
    Colorectal cancer research via GWAS
    Genomic data analytics vs bioinformatics master’s degrees
    In-demand skills for data analysts
    Pre-requisites to apply to master’s programs, epscally KGI
    Advice for students applying to programs
    Content and skills taught in the data analytics program
    Employers of alumni of the data analytics program

    Check out the article we mention in the episode about what you can do with a degree in data analytics. Here you can find further information about KGI’s genomic data analytics program.

    Stay tuned for the next new episode of DNA Today on March 19th, 2021! We will be joined by another one of our sponsors, ATGC, to kick off our telehealth series.

    New episodes are released on the first and third Friday of the month. In the meantime, you can binge over 140 other episodes on Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “DNA Today”. Brand new in 2021, episodes are now also recorded in video which you can watch on our YouTube channel.

    See what else we are up to on Twitter, Instagram, Facebook, YouTube and our website, DNApodcast.com. Questions/inquiries can be sent to info@DNApodcast.com.

    • 30 min
    #141 Stan Crooke on Ultra Rare Disease Drugs

    #141 Stan Crooke on Ultra Rare Disease Drugs

    Biotech titan Dr. Stan Crooke joins host Kira Dineen to celebrate rare disease month! Dr. Crooke was the Founder of IONIS Pharmaceuticals, with extensive experience in the pharmaceutical industry developing more than 20 marketed drugs. He has published nearly 500 scientific publications, edited more than 20 books, and has numerous patents.

    Dr. Stan Crooke is now the Founder and CEO of n-Lorem Foundation, a new San Diego-based organization with an incredible mission of developing individualized RNA targeted medicines for patients with ultra-rare diseases, and providing those treatments for free, for life. These patients have extremely unique mutations and are often only one of 30 people in the entire world to have the disease. After only one year as a foundation, they’ve already made great progress for the ultra rare community, having received 50 applications from patients with ultra rare genetic mutations. Out of those 50, they have greenlighted treatment plans for nearly 20 patients - greatly exceeding application and acceptance rate expectations.

    On This Episode We Discuss:
    Rare diseases vs ultra rare diseases
    Challenges treating patients with ultra rare diseases and genetic mutations
    Standard process and cost of drug development
    n-Lorem’s new approach to drug development for ultra rare diseases
    Antisense therapies (ASOs)
    n-Lorem’s charitable and scalable model
    n-Lorem’s relationship with IONIS Pharmaceuticals
    People eligible for n-Lorem’s treatments
    How to contact n-Lorem’s for potential treatment
    Drugs currently in development at n-Lorem
    Insight on the development of SPINRAZA® for spinal muscular atrophy

    Learn more about n-Lorem on their website.

    Check out the UConn Podcast Symposium, our host Kira Dineen will be on the interdisciplinary panel taking place on February 22nd at 4PM EST. You can register to attend for free here. UConn students will be provided a Zoom link to engage in a live Q&A. The panel will also be streamed publicly via Facebook and YouTube.


    Stay tuned for the next new episode of DNA Today on March 5th, 2021! New episodes are released on the first and third Friday of the month. In the meantime, you can binge over 140 other episodes on Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “DNA Today”. Brand new in 2021, episodes are now also recorded with video which you can watch on our YouTube channel.

    See what else we are up to on Twitter, Instagram, Facebook, YouTube and our website, DNApodcast.com. Questions/inquiries can be sent to info@DNApodcast.com.

    #140 Patti Hall on Gigantism

    #140 Patti Hall on Gigantism

    To kick off rare disease month, author Patti M. Hall joins host Kira Dineen to discuss her memoir Loving Large which chronicles her son’s rare disease diagnostic odyssey. Her life was pitched into an abyss of uncertainty when a golf ball–sized tumour was discovered in her teenage son’s head and he was diagnosed with gigantism, a disease of both legend and stigma. After scrambling to access a handful of medical experts in the field, Patti learned that her son could grow uncontrollably, his mobility could be permanently limited, and his life could be cut short without timely and aggressive treatment. Patti’s attention shifted fully to her son, away from her relationships as well as her own career and health. Her new normal sees her step into a dozen additional roles, including nurse, researcher, advocate, risk assessor, and promise maker, while she struggles and fails to rebuild her life as a recently divorced woman. When the unthinkable strikes, parents Love LARGE. Now, Patti serves as an advocate for the rare disease community by serving as a member of the Board of Directors for AcromegalyCanada.

    Enter our giveaway here to win your own copy of Loving Large! For additional entries head over to our Instagram post.

    This episode is brought to you by Picture Genetics, a unique DNA testing service, with tests designed for every stage of life -- including family planning. With a Picture Parenting carrier test, you can uncover genetic conditions that may be passed on to your kids (such as cystic fibrosis or fragile X syndrome). Unlike other companies, this is actually a clinical grade test where physicians and genetic counselors are involved. It’s easy to order and understand with good looking reports! To order your Picture Genetics test, go to picturegenetics.com and use code “DNATODAY” for 25% off and free-shipping! Get actionable genetic insights today to benefit your family of tomorrow. 

    On This Episode We Discuss:

    Diagnostic Odyssey “From sore knees to a brain tumor”
    Symptoms of gigantism
    Gigantism vs Acromegaly
    Joining the rare disease community
    Mother son relationship through diagnosis and treatments
    Filtering medical information for rare disease kids
    Impact of a rare disease on siblings
    Genetic research for gigantism
    Sequel to Loving Large

    Learn more about Patti Hall on her website and stay updated with her writing and advocacy on her Instagram. Her podcast, “Reframe your Life” addresses issues relevant to women beyond career building and child-rearing.

    Don’t forget to enter our giveaway for a copy of Loving Large here. You can also get extra entries through our Instagram!

    Continue our rare disease month celebrations with the next new episode of DNA Today on February 19th! You can also hear 20+ rare disease interviews on previous episodes of the show listed here.

    New episodes are released on the first and third Friday of the month. In the meantime, you can binge over 130 other episodes on Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “DNA Today”.

    See what else we are up to on Twitter, Instagram, Facebook, YouTube and our website, DNApodcast.com. Questions/inquiries can be sent to info@DNApodcast.com.

Top Podcasts In Science

Listeners Also Subscribed To