Scrubcast

Stanford Surgery

The Department of Surgery at Stanford University

  1. Where Cancer and Cardiovascular Health Meet with Dr. Nazish Sayed

    6 DAYS AGO

    Where Cancer and Cardiovascular Health Meet with Dr. Nazish Sayed

    Scubcast welcomes back Dr. Nazish Sayed, an associate professor in the Division of Vascular Surgery, for a discussion on the latest research in cardio vascular health. In this episode, Dr. Sayed reflects on the enduring benefits of statins, delves into the intricacies of tyrosine kinase inhibitors and their effects on vascular endothelial cells, and introduces innovative approaches in studying vascular Ehlers Danlos syndrome. He also shares personal experiences as both a clinician and cancer survivor, shedding light on the emotional journey of patients navigating "scanxiety." Tune in to explore cutting-edge advancements in cardio-oncology and precision medicine that promise to improve patient care and outcomes in this fascinating field.

    20 min
  2. Exploring the Intersection of Surgery and Cancer Research with Dr. Dan Delitto

    2 FEB

    Exploring the Intersection of Surgery and Cancer Research with Dr. Dan Delitto

    Dr. Dan Delitto is an assistant professor of surgery at Stanford University specializes in surgical oncology and holds a PhD in immunology. On this episode, Dr. Delitto reflects on his decision to pursue an MD-PhD pathway during residency and discusses the recent advancements in single-cell RNA sequencing technology that his lab has acquired. He explains the complex role of fibroblasts in cancer development, particularly in pancreatic ductal carcinoma, highlighting how these cells can both promote and hinder tumor growth. The conversation includes a lightning round, during which Dr. Delitto shares his admiration for his mentor, Steve Hughes, and offers succinct advice on the importance of surgical experience. He also mentions his preference for trance music while working and shares his excitement about ongoing and future research projects in his lab, which include investigations into various cancers, such as sarcomas. Link to Nature Cancer article “Cancer-derived mitochondria fuel fibroblasts to become pro-tumorigenic.”: https://www.nature.com/articles/s43018-025-01005-1 Link to Cell Reports article “Disruption of fibroblast MYD88 signaling promotes antitumor immunity in pancreatic ductal adenocarcinoma”: https://www.cell.com/cell-reports/fulltext/S2211-1247(25)01118-0?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2211124725011180%3Fshowall%3Dtrue

    14 min
  3. 20 years of Improving Transplant Tolerance with Dr. Stephan Busque

    01/12/2025

    20 years of Improving Transplant Tolerance with Dr. Stephan Busque

    This episode features Stanford Professor and transplant surgeon Dr. Stephan Busque. He discusses his extensive experience in the field of tolerance in transplantation, particularly focusing on advancements over the past 20 years. Dr. Busque highlights the significance of his team's work on translating research into clinical practice and mentions that they have the largest experience globally in this field. Additionally, Dr. Busque shares exciting news about Stanford's first allogenic islet cell transplantation for a patient with type one diabetes, indicating a collaborative effort that brought together a multidisciplinary team to achieve this milestone. He reflects on the journey of making islet cell transplants more accessible and expresses hope for new beginnings in this area. The episode wraps up with a lightning round where Dr. Busque discusses the qualities he admires in skilled surgeons, emphasizing the importance of being a well-rounded doctor who not only excels in technical skills but also demonstrates a deep understanding of patient care and connection. Going forward he’s excited for the development of protocols for various transplant scenarios, including open liver transplant tolerance, and indicates that patients with less-than-perfect matches are the next target group for improvements in transplantation techniques

    30 min
  4. Crohn's Disease and Creeping Fat with Dr. Jeong Hyun

    03/11/2025

    Crohn's Disease and Creeping Fat with Dr. Jeong Hyun

    On this episode of Scrubcast, episode of Scrubcast features Dr. Jeong Hyun, an assistant professor in the division of pediatric surgery at Stanford University, discusses his journey to becoming a surgeon scientist. Hyun’s research is focused on Crohn's disease and how strictures develop in the intestines. Shout out to MD/PhD candidate Khristian Bauer-Rowe, who he collaborated with on the September article in Cell looking at the role of creeping fat and CTHRC1+ fibroblasts. The episode also touches on Dr. Hyun's personal interests, including his unexpected love for country music, which he developed while working in Kansas City. The discussion concludes with Dr. Hyun acknowledging the uncertainties in research funding and the importance of vulnerability and resilience in both personal and professional life. Link to article: https://www.cell.com/cell/abstract/S0092-8674(25)01018-9

    28 min
  5. Advancements in Breast Cancer Treatment with Dr. Fred Dirbas

    01/10/2025

    Advancements in Breast Cancer Treatment with Dr. Fred Dirbas

    On this episode of Scrubcast, we speak with Dr. Fred Dirbas, the John and Ann Doerr Faculty Scholar of Breast Surgery and chair of the breast disease site working group for the Society for Surgical Oncology. Rather than ascribing to a particular set of screening recommendations, Dr. Dirbas advocates for personalized screening strategies, particularly for women with a family history of breast cancer He discusses his innovative work in FLASH radiotherapy, which aims to minimize side effects typically associated with traditional radiation, and his research on triple-negative breast cancer (TNBC), focusing on identifying subpopulations of TNBC stem cells through molecular profiling.

    29 min
  6. Adolescent Obesity and Bariatric Surgery with Dr. Janey Pratt

    02/09/2025

    Adolescent Obesity and Bariatric Surgery with Dr. Janey Pratt

    Clinical Professor Dr. Janey Pratt shares her passion for working with children and discusses the pressing issue of childhood obesity. As an adolescent bariatric surgeon, Dr. Pratt emphasizes that obesity is a disease. Although GLP1s — like Wegovy and Ozempic — offer some help, Dr. Pratt describes a multitude of evidence indicating surgery is a safe and more effective solution. In addition to surgery, Dr. Pratt also sheds light on Stanford’s comprehensive preoperative process for adolescent bariatric surgery, including necessary testing and evaluations to ensure patient safety as well as diet and exercise education for the whole family.

    20 min
  7. Empathy and Innovation in Microsurgery with Dr. Arash Momeni

    01/08/2025

    Empathy and Innovation in Microsurgery with Dr. Arash Momeni

    In this episode of Scrubcast, we sit down with Dr. Arash Momeni, an associate professor at Stanford University’s Department of Surgery, to discuss the latest advancements in reconstructive microsurgery. From his recent clinical trial—an anticoagulant head-to-head—to the integration of augmented reality (AR) technology in surgical practice, he is always looking for new ways to enhance precision, safety, and patient comfort. Dr. Momeni also provides a comprehensive overview of the emotional and logistical complexities faced by patients diagnosed with breast cancer, emphasizing the importance of empathy and education in the surgical process. Additionally, Dr. Momeni discusses his unique path to Stanford (completing residency TWICE) and his experiences with the American Society for Reconstructive Microsurgeons (ASRM) as the 2023 Godina Fellow and now Secretary. PRSJournal video: https://www.youtube.com/watch?v=GfLv2vogk5A Godina Lecture: https://www.youtube.com/watch?v=p_kPPUy7vLM Clinical Trial: https://pubmed.ncbi.nlm.nih.gov/40327806/

    21 min
  8. Revolutionizing Vascular Health with Dr. Nick Leeper

    01/07/2025

    Revolutionizing Vascular Health with Dr. Nick Leeper

    In this episode of Scrubcast, we sit down with Dr. Nick Leeper, Chief of Vascular Medicine at Stanford University, to explore his groundbreaking research in cardiovascular disease. Dr. Leeper shares his lab's unique "hypothesis-free" methodology, where they analyze the entire genome to uncover genetic variants associated with heart disease. Additionally, Dr. Leeper highlights his collaborations with experts outside the School of Medicine to develop treatments straight out of science fiction. Read Leeper’s Article in Nature Communications: https://pmc.ncbi.nlm.nih.gov/articles/PMC11399336/ Throughout the episode, Dr. Leeper emphasizes the importance of perseverance in research, drawing inspiration from Drs. Norm Shumway and Ron Dalman.

    20 min
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About

The Department of Surgery at Stanford University

Information

  • Creator
    Stanford Surgery
  • Years Active
    2022 - 2026
  • Episodes
    52
  • Rating
    Clean
  • Copyright
    © All rights reserved
  • Show Website
    Scrubcast