21 min

Research focus: the role of TRAIL in premetastatic niche formation in breast cancer The Cancer Researcher Podcast

    • Ciencias de la vida

When studying TRAIL expression in the tumour stroma, Dr Massimiliano Mazzone and Dr Carla Riera-Domingo made a surprising discovery with great therapeutic potential: this immunoregulator acts as a gatekeeper of the vasculature at the pre-metastatic niche. Listen to this episode to find out what implications this has for the formation of the premetastatic niche and the therapeutic value this novel finding holds.
You can also read the full episode transcript here: magazine.eacr.org/the-role-of-trail-in-premetastatic-niche-formation-in-breast-cancer-episode-11-of-the-cancer-researcher-podcast
This study has been published in Science Advances 9 (12), eadd5028. DOI: 10.1126/sciadv.add5028 and was included in the EACR's Highlights in Cancer Research.

When studying TRAIL expression in the tumour stroma, Dr Massimiliano Mazzone and Dr Carla Riera-Domingo made a surprising discovery with great therapeutic potential: this immunoregulator acts as a gatekeeper of the vasculature at the pre-metastatic niche. Listen to this episode to find out what implications this has for the formation of the premetastatic niche and the therapeutic value this novel finding holds.
You can also read the full episode transcript here: magazine.eacr.org/the-role-of-trail-in-premetastatic-niche-formation-in-breast-cancer-episode-11-of-the-cancer-researcher-podcast
This study has been published in Science Advances 9 (12), eadd5028. DOI: 10.1126/sciadv.add5028 and was included in the EACR's Highlights in Cancer Research.

21 min