The Medtech Impact Podcast Kyle Kruse (@Medtech_Missile) & Richard Meiklejohn (@InnovationBeacon)

Transforming the outcomes for a disease takes great innovation. With that, you need impeccable dedication and leadership for the team to deliver on taking a solution to market. Former CEO of LimFlow, Dan Rose, is one such leader who can attest to the trials and tribulations of this challenging journey.Dan joins this episode to share the story of how LimFlow’s technology has gone from an idea with potential, to a life-saving solution. In achieving this, the company has been able to re-design the anatomy of the body to offer hope to those suffering the effects of Chronic Limb-Threatening Ischemia (CLTI).During this discussion you will learn the despairing depths of a disease that is quite literally ravaging people’s lives. Dan shares how he was able to build a world class team from across the globe to design a new option for patients where none existed before. Navigating numerous challenges, raising significant amounts of capital, and leading the company to a successful acquisition by Inari Medical; From beginning to end, this tale will truly leave you informed and inspired.

Research suggests that women are more likely to experience joint pain, aching, and stiffness caused by arthritis or arthritic conditions. In fact, evidence suggests that women aged 50 to 60 years may be 3.5 times (350%) more likely to develop CMC osteoarthritis than men in the same age group.CEO and co-founder of Grace & Able, Sarah Dillingham, is one such arthritis sufferer. Following a life-changing moment, she decided to tackle the lack of suitable relief products for women. Through building an entire support community, Sarah has connected directly with those experiencing arthritis to offer a customized solution for women.The main symptoms of arthritis are joint pain, inflammation, and stiffness, which typically worsen with age. The most common types of arthritis are osteoarthritis and rheumatoid arthritis. Osteoarthritis causes cartilage — the hard, slippery tissue that covers the ends of bones where they form a joint — to break down. Rheumatoid arthritis is an autoimmune disease in which the immune system attacks the joints, beginning with the lining of joints. The main goals of arthritis treatments are to reduce symptoms and improve quality of life.In this episode you will learn what it takes to turn from patient to advocate to brand and product leader. Brand authenticity is something many companies aspire to, Sarah’s genuine and respectful approach with customers to truly understand their needs is something that any entrepreneur could learn from. With this universal design approach, she has been able to create value driven relationships to help grow the business. This is definitely a discussion that will leave you informed and inspired.

What are metamaterials and how can they help improve the performance of MRI?? Step forward Ryan Mcnaughton, CEO and co-founder of Primetaz to reveal how their technology is set to dramatically enhance both the quality of imaging but more importantly, offer game-changing time-saving to a process that is seeing significant growing demand.MRI has become one of the most important tools for doctors to see inside the body to understand what is happening in disease. MRI shows soft tissues like the brain, the heart, and other muscles and organs. It provides several ways to view the status of the tissue, such as looking at the shape, changes to the structure, blood flow, and inflammation. Being able to see inside the body quickly and clearly has led to advanced treatments and longer, healthier lives. Given the every increasing demand for MRI as a flexible imaging technique, many physicians, scientists, and engineers like Ryan continue to develop new ways to see disease earlier, enabling more effective treatments.While sharing the mission & motivation behind Primetaz, Ryan reveals insights that many entrepreneurs will readily relate to as well as detailing a vision that will excite both investors, patients, and physicians alike. Turning from engineer or any technical profession to entrepreneur is always a journey, and Ryan’s dedicated approach is sure to leave you inspired and informed.

Thirona’s CEO and Founder, Eva van Rikxoort, joins this episode to share how their FDA-approved device is now integrating into the clinical workflow to both enhance physician performance and patient outcomes. LungQ is built on more than 10 years of clinical trials and 200+ publications to utilize AI allowing automatic segmentation of pulmonary segments and subsegments found in the internal anatomy of the lung.This clearer understanding of lung anatomy helps enable broader adoption of minimally invasive treatments for lung diseases such as COPD and lung cancer, helping save more healthy lung tissue and lung function capacity. Acting as a map for lung anatomy, LungQ helps guide bronchoscopic navigation, leveraging AI to significantly enhance the precision, accuracy, and efficiency of bronchoscopic and surgical lung interventions.With such emerging AI applications comes a wonderful story of a mission-driven team that is connecting across continents to bring new levels of precision and accuracy to patients. As a scientist turned entrepreneur, Eva demonstrates all the characteristics of a great leader who is building a collaborative model for success. If you’re looking to learn how AI-powered software should be leveraged, then tune in to be informed and inspired.

Breaking bones is unfortunately a common part of life; in fact doctors treat about 6.8 million fractures each year in the United States alone, and the average person can expect to sustain two fractures over their lifetime. In this episode, we are joined by Brian Hess, CEO and Founder of RevBio, who is helping to transform bone repair with their innovative adhesive. Not only is this solution boosting how bones can rapidly fuse back together through its biomimicry properties, this is a product that stimulates bone growth and leaves no artifact in the body.From raising nearly $20 million in non-dilutive funding, it’s clear that this technology has huge potential with multiple indications available to be applied to. Brian lays out a clear strategic path to market that includes the opportunity to leverage early animal studies with veterinarians also seeing significant value from this exciting technology in the near term.Throughout this discussion, Brian displays all the attributes of a great leader, with a top co-founder coupled alongside in Grayson Allen, they have developed a winning culture, and a team that thrives on the opportunities they are given to both develop personally and help take this product to market.As a UMass M2D2 resident, RevBio is able to access a number of resources and an incredible pipeline of young talented interns who have grown with the company and stepped up into more senior roles. This is a startup story that is packed full of the hallmarks for building a successful innovative medical solution, and one that is sure to leave you informed and inspired.

Benign prostatic hyperplasia (BPH), also known as enlarged prostate, has been in the headlines recently with Britain's King Charles revealing plans earlier this year to have a corrective procedure to alleviate the associated symptoms. In this episode, Tushar Sharma, Vivifi Medical’s CEO and Founder, joins us to guide listeners through an amazing anatomical insight of the condition and their novel treatment.An enlarged prostate is a fact of life for the majority of men as they age. Due to the prostate’s close proximity to the urethra which carries urine from the bladder, pressure can build on this vessel as the prostate expands, leading to a range of associated urinary issues. Depending upon the severity of the patient's symptoms, different surgical techniques may be needed to alleviate these, with doctors often considering invasive surgery the best long-term option for relief of more bothersome effects.Under the leadership of Tushar, their exciting solution holds significant promise and despite its early development stage, has already received excellent feedback from surgeons. With such an innovative technology, comes a complex set of product development, clinical, regulatory, and reimbursement challenges. Tushar’s passion for bringing their product to market shines throughout this discussion, and his meticulous manner in solving these challenges is sure to leave you informed and inspired!