16 episodios

Interviews from the WCCS 2016 conference.

WCCS 2016 ecancer

    • Medicina

Interviews from the WCCS 2016 conference.

    • video
    Causes, symptoms, and prevention of skin cancer

    Causes, symptoms, and prevention of skin cancer

    Dr Marmol meets with ecancertv at WCCS 2016 to discuss the outcomes of the Euro Melanoma campaign to raise public awareness of the causes, symptoms, and prevention of skin cancer.

    Looking at data gathered from participating European countries regarding sun-bed use over the years, she describes an increased awareness and attendance of melanoma screening.

    In comparison to attitudes towards other behaviours associated with increased risk of disease, specifically smoking, Dr Marmol highlights the ongoing need for wider engagement with preventative measures.

    • 4 min
    • video
    Developments in checkpoint immunotherapy

    Developments in checkpoint immunotherapy

    Dr Larkin speaks with ecancertv at WCCS 2016 about developments in checkpoint immunotherapy.

    He discusses results from recent trials of single agent, combined and adjuvant immunotherapy compared to targeted therapies, with regards to overall survival, subgroups determined by biomarkers, and complementary mechanisms.

    With regard to public awareness of melanoma, Dr Larkin highlights successful international campaigns and the remaining need in some populations for preventative measures to limit UV exposure.

    • 6 min
    • video
    Skin cancer lesions arising in uncommon regions

    Skin cancer lesions arising in uncommon regions

    Dr Malvehy speaks with ecancertv at WCCS 2016 about skin cancer lesions arising in uncommon regions.

    He describes the criteria by which dermatologists might investigate and accurately diagnose early melanoma, depending on the presentation of a wide constellation of symptoms.

    Dr Malvehy outlines how clinicians can remain up to date with the latest in skin cancer diagnostics, and the promise of current research for patients in the near future.

    • 5 min
    • video
    Targetted medicine to reduce melanoma mutational burden

    Targetted medicine to reduce melanoma mutational burden

    Prof McArthur speaks with ecancer at WCCS 2016 about targetted medicine to reduce melanoma mutational burden, with specific focus on the BRIM trials of cobimetinib and vemurafinib.

    He outlines the expansion of personalised therapy and genotyping for improved duration and depth of response, considering the push from other quarters towards sequencing for all patients, and his hopes for the future of cancer vaccines.

    However, Prof McArthur notes that these results do not indicate clinical readiness, and highlights brain metastases in melanoma as an area in need of further research.

    • 6 min
    • video
    VISMO trial to treat basal cell carcinoma

    VISMO trial to treat basal cell carcinoma

    Dr Hauschild speaks with ecancertv at WCCS 2016 with updates from recent trials in checkpoint inhibition therapy.

    He discusses the Hedgehog inhibitor tested through the VISMO trial to treat basal cell carcinoma, and the BRIM trials of vemurafinib ± cobimetinib.

    Dr Hauschild also considers the the results of Checkmate and Keynote trials of PD1/PDL1 biomarkers presented as ASCO 2016 and the economic viability of these treatments across Europe.

    • 5 min
    • video
    Checkpoint inhibitor therapy for treating melanoma

    Checkpoint inhibitor therapy for treating melanoma

    Dr Weber speaks with ecancertv at WCCS 2016 about checkpoint inhibitor therapy for treating melanoma.

    He outlines ongoing and upcoming trials of PD-1/PD-L1 based immunotherapy, as well as immune modulation via OX40 and 41BB antibodies.

    Dr Weber also highlights the therapeutic potential of combining immunotherapy with surgery, chemotherapy and most notably radiotherapy, in which radiation can be used to 'warm up' a 'cold' tumour, allowing the inflammation of radiation-damaged cells to recruit a greater immune response than immunotherapy alone.

    • 5 min

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