"If we learn to see problems in terms of a general disorder of energy metabolism, we can begin to solve them." —Raymond Peat PhD
#64: Life | Energy | Estrogen | Fibrosis | Calcification | Process Theology | Altruism with Ray Peat
00:00 - Skip setup music, Ray's July newsletter, lipofuscin, estrogen, fibrosis
03:47 - What is the standard medical view of fibrosis? What is Ray's view?
06:13 - Is fibrosis the result of excessive cellular reduction? Intracellular calcium, PTH, iron
20:50 - What organismc signal leads to the development of a tumor? Inflammation, fibrosis, calcification
14:05 - What hormones are coordinating fibrosis? Estrogen, PTH, prolactin, aldosterone, growth hormone, serotonin, TSH, gonadotrophins
16:12 - What's the role of the prostaglandins and leukotrienes? "Essential fatty acids," mead acid
19:41 - Ray's various "names" for hormones: estrogen, aldosterone, serotonin, prolactin
23:02 - Prolactin, estrogen, activation of stem cells
23:21 - What's the role of fibrin in fibrosis? Iron, ferritin, hepcidin, vitamin E
29:00 - Does every viral infection involve inflammation? Exosomes, retroviruses
32:15 - How to subscribe to Ray's newsletter, order Ray's books, Progest-E from Kenogen, topical application of progesterone with olive oil
40:39 - Ray on David E. Martin's work, Eric Schmidt, empire wars, artificial intelligence
44:56 - 'China are better capitalists than their opposition'
46:24 - 'It could reduce world population by 80-90%'
51:41 - "More life and more energy can solve many of the basic problems of life." Ray Peat (1994)
53:15 - Einstein, space-time, Michelson-Morley aether
56:11 - Question: What is a healthy way to look at the world? What is an unhealthy way to look at the world?
58:40 - Question: Ray's take on process theology, David Ray Griffin
1:02:28 - Suspending judgment as a quality of a high metabolic rate
1:03:08 - Question: Ray's take on Marx's scientific method and social revolution, Nelson Rockefeller, Christian communism, Rothschilds, Club of Rome, WEF
1:06:43 - Question: How much does intuitive thinking coincide with intellectual processing? Altruism, basic needs, injury
1:10:48 - Question: Is seeking revenge always serotonergic? Alice Miller, Weillhelm Reich, love
1:18:08 - Question: How does the mind affect biological processes? Routine vs. novelty
1:22:02 - Question: How to reset trauma in a tortured dog
1:23:07 - Question: What are Ray's thoughts on 'planes of existence? Why did the second signal system evolve?
#63: Immunity | Vitamin D | Infertility | Vitamin E | Cardiolipin | PUFA | Aging with Georgi Dinkov
00:00 - Catch-up chat, David E. Martin, cyberattack, transhumanism, Georgi's hospital experience
34:58 - Variants
38:03 - Miscarriage
45:06 - Idealabs update
50:21 - Vitamin E for immunity, AIDS
59:32 - Vitamin D improves ovarian reserves in women with infertility, Kate Deering and Kitty Blomfield interview Ray Peat about vitamin D
01:03:10 - Aging is an energy deficiency problem, taking cardiolipin may reverse it, PUFA, lipid peroxidation
01:08:48 - Idealabs update, outro
#62: Diabetes | CO2 | Mineral Balancing? | Coenzyme Q10 | Cognitive Capture | Parathyroid Hormone with Georgi Dinkov
00:00 - Start, catch-up with Georgi, farming, covid death statistics, the Pentagon is gross
22:51 - Study finds intense training sessions temporarily impair mitochondrial function
34:03 - The interplay between the renin-angiotensin-aldosterone system and parathyroid hormone, sodium, CO2
42:40 - The effect of dietary PUFA on cation transport and hypertension in the rat
45:17 - COQ10 protects from aging-related oxidative stress and improves mitochondrial function in the heart of rats fed PUFA-rich diet, the difference between ubiquinone (oxidized) and ubiquinol (reduced), ROS
52:06 - Idealabs update, naringenin, apigenin
01:11:34 - PUFA impair blood glucose control in type 2 diabetic patients, hyperglycemia as the result of metabolic stress (not high carbohydrate intake), PUFA and ACTH
01:19:51 - Advanced age, but not anergy, is associated with altered serum polyunsaturated fatty acids levels
01:21:55 - Sci-Hub lawsuit, Alexandra Elbakyan is a science hero, Aaron Swartz
01:31:28 - Neuronal lipolysis participates in PUFA-meditated neural function and neurodegeneration
01:32:18 - Idealabs update, serotonin antagonist (tropoxin)
#61: Bodybuilding and Steroids | Progesterone for Men? | Basic Bioenergetic Therapies with Ray Peat and Georgi Dinkov
00:00 - Start, why are we doing a fundraiser?
01:58 - Trestolone 7α-methyl-19-nortestosterone (MENT), activation of the androgen receptor, adding a methyl group to a steroid makes it risky
04:46 - What would Ray do if he had Crohn's disease? Mycobacteria, supplementing with cellulose
09:56 - Cortisol blockers for weight loss? Progesterone, thyroid
10:38 - Do you want to increase ceruloplasmin? Copper toxicity
12:55 - Does nitric oxide work like viagra?
14:36 - Lactose-free milk and is aspirin safe to take every day?
15:43 - Low sperm count, varicocele, aspirin, progesterone, thyroid, testosterone, estrogen
18:14 - Ray's thoughts on ivermectin, vitamin D, coronavirus
22:46 - Hypothyroidism in children?
24:53 - Can thyroid hormone lower the temperature?
28:20 - Why are people getting flu and cold symptoms right now?
30:03 - Is vaccination a tradeoff?
32:19 - What steroids would be useful for building big muscles? Testosterone, estrogen, DHEA, 'thyroid is the basic anabolic hormone'
36:52 - Sleep apnea, CPAP, CO2, hypothyroidism, progesterone, acetazolamide
40:26 - Diabetic pain in the feet, T4 only therapy, thyroid gland removal, armour, cynoplus, cynomel
43:02 - Progest-E by Kenogen, email Katherine at email@example.com, progesterone as a basic stabilizing factor
44:58 - Ray's thoughts on ethically composing a "cosmic diet"
46:25 - Benign tumor metabolism, progesterone, fibrosis, estrogen, nitric oxide
48:38 - Gynecomastia, vitamin D, progesterone, thyroid, aspirin
49:25 - When did the U.S. transform into an empire?
52:26 - Inability to ejaculate and get an erection, getting blood tests, low heart rate, hypothyroidism
54:49 - Herbs for DHT production?
55:29 - Can T3 harm the thyroid gland if used chronically?
58:17 - Pregnenolone, adrenal suppression, progesterone, stress
01:02:29 - Increasing libido and energy in a young woman after childbirth, vitamin D, calcium, thyroid
01:03:31 - How to reverse the aging process? CO2 as a cardinal adsorbent, flavanoids, fisetin
01:11:26 - Raising levels of the ACE2 enzyme for health, anti-viral effects of progesterone
01:14:06 - Getting rid of acne scars
01:15:12 - Taking thyroid but the morning temperature isn't increasing
01:16:01 - Diabetes, swollen purple legs, and significant edema, vitamin D, calcium, progesterone, thyroid, a lower-fat diet
01:17:27 - Best things to increase mitochondrial function, CO2, angiotensin inhibitors
01:18:17 - Correcting a thyroid nodule, TSH
01:19:03 - Excess saliva
01:19:35 - 16-year old breast cancer, estrogen, progesterone, aspirin, thyroid
01:20:18 - T3 and body odor, sulfur soap
01:21:09 - Nicotine as a prometabolic substance?
01:22:49 - How to lengthen the luteal phase?
01:23:45 - A daily progesterone amount for men?
01:25:20 - Is the Herxheimer reaction real? Harry Rubin's findings about cancer treatment
01:29:15 - A bioenergetic view of THC and CBD?
01:31:10 - Ray's essential 'prepper' food items
01:34:16 - Lump in the throat from cynoplus and cynomel, how much is too much with T3? Does Ray chew the cynoplus/cynomel?
01:36:16 - Varicose veins from progesterone or pregnenolone? What's a big dose of progesterone?
01:39:16 - What does Ray think of the croissant diet?
01:40:29 - What amount of alcohol is enough for lipofuscin?
01:41:18 - How to restore the outer layer of the adrenal gland?
01:42:12 - Can the temperature and pulse be maintained by stress? How long does it take to adapt to a thyroid supplement?
01:45:19 - What is Ray working on right now?
01:46:45 - Magnetofection?
01:48:04 - How to use progesterone to post-pone menopause?
01:49:36 - Benefits of allopregnanolone?
01:49:51 - Very dry palms, hypothyroidism, sebum, sweat
01:50:31 - How to tell if sugar is converting into CO2 or lactic acid?
01:50:59 - 1000 calories for weight loss? RU486 cortisol blocker, how many calories to eat?
01:53:44 - Kids dying as the result of vaccination
#60: PUFA as a Mitochondrial Toxin | Vitamin D, Inflammation, and Aging | Iron, Copper, and Anemia with Georgi Dinkov
00:00 - Skip setup music, catching up with Georgi, Eric Schmidt, automation, A.I., depopulation
26:38 - Mitochondrial dysfunction may be the cause of anemia, iron, copper, ceruloplasmin, ferritin
37:15 - Upregulated serotonin synthesis may be a biomarker for breast cancer, lidocaine for digestion, olive oil
50:13 - Idealabs update
01:00:37 - Vitamin D may treat (opioid) “addiction," PTH, tryptophan hydroxylase, serotonin, pregnenolone, "post-finasteride syndrome"
01:13:02 - PUFA deficiency reverses effects of alcohol on mitochondrial energy metabolism, cardiolipin, cytochrome c oxidase, electron flow, nitric oxide
01:19:57 - Outro chat, hypothetical power and water outages
#59: PUFA, Aggression, and Puberty | Insomnia and Serotonin | Cortisol, Obesity, and Diabetes
00:00 - Skip Setup music, catch-up with Georgi, JBS "cyberattack," World Economic Forum, UFOs
12:11 - Georgi's Strong Sista's interview, problems with low-carb
15:35 - Maternal high-PUFA diet causes alcoholism, aggressiveness, early puberty, and hyper-estrogenism in offspring, PUFAs are estrogenic
25:13 - Stress ups cortisol/estrogen/prolactin, drops DHT, causes male infertility and prostate issues
33:07 - Idealabs update, drupanol
39:32 - Hyperserotonemia confirmed as a cause of autism and insomnia, ways to lower serotonin, aspirin, salt
58:05 - Hidut's Bulgarian Bioenergetic Burger™ Recipe
01:10:38 - Cortisol causes fatty liver (as well as obesity, diabetes, etc.), saturated fat
01:04:11 - Working too hard / long can kill you, finding meaningful work
01:13:58 - High PTH, low vitamin D implicated in bipolar disorder (BD)
01:23:18 - 'It takes 30-50 years to know the side effects of a new drug'
01:34:49 - Danny thinks this is the calm before the storm, outro