6 episodes

Join Dr Karan, TikTok's favourite General Surgeon, as he meets the world's foremost experts in science and medicine to cut through the BS of modern health advice.

Dr Karan Explores OG Podcasts

    • Health & Fitness

Join Dr Karan, TikTok's favourite General Surgeon, as he meets the world's foremost experts in science and medicine to cut through the BS of modern health advice.

    The Ultimate Guide to CBD - Dr Jeff Chen

    The Ultimate Guide to CBD - Dr Jeff Chen

    “Like most other herbal medicines, CBD is understudied, unregulated, and often wrongly vilified.” -Dr Jeff Chen

    Dr Jeff Chen is co-founder of Radicle Science and is doing tons of research advancing our understanding of CBD and other herbal remedies.

    In this episode, I ask Jeff about the new science of CBD - both its potential health benefits and challenges. We also explore the promising trials into another cannabis compound - CBN.

    Stay tuned to find out:


    How effective CBD is for sleep, anxiety, pain and more
    How stigma and regulatory hurdles have hampered scientific progress
    What you should be looking for when buying CBD products
    How Radicle’s crowd-sources clinical trials are shedding light on many herbal remedies

    Chapters

    (1:54) What is CBD?

    (3:27) Why herbal remedies are dismissed

    (8:59) Crowd-sorucing data on CBD and CBN

    (14:13) Avoiding bias and determining placebo

    (19:46) Science of the endocannabinoid system

    (25:11) Safety of OTC CBD supplements

    (29:30) Optimal delivery route of CBD

    (33:21) Best cases for CBD in clinical settings

    (36:46) Choosing the right product - an unregulated market

    (48:07) Benefits of lion’s mane mushrooms

    Connect with me:

    TikTok: https://www.instagram.com/drkaranrajan

    Instagram: https://www.tiktok.com/@dr.karanr

    For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook

    An OG Podcasts production.

    • 52 min
    The Problem with Ozempic - Dr Andres Acosta

    The Problem with Ozempic - Dr Andres Acosta

    “Ozempic has changed the conversation around obesity. Unfortunately a lot of people are misusing the medication.” -Dr Andres Acosta

    Dr Andres Acosta is an obesity expert at the Mayo Clinic, and regularly helps patients achieve double digit weight loss thanks to semaglutide, often branded as Ozempic or Wegovy. But as healthy people look to it for a quick fix, he raises a red flag about the drug.

    In this episode I ask Andres how Ozempic works, what are its side-effects, and who should actually be taking it. Plus what else works for treating obesity.

    Stay tuned to find out:


    The risks and rewards of Ozempic
    What’s going on in the brains of people who struggle with their weight
    How his lab has identified 4 genetic phenotypes causing obesity
    Where Dr Acosta stands on “body positivity”
    How his work is destigmatising obesity
    How close we are to a cure

    Chapters

    (1:55) Misusing Ozempic

    (4:35) Ozempic for longevity and health

    (7:49) Diet and exercise vs Ozempic + risks

    (10:55) Do you need to take Ozempic forever?

    (14:24) Link between the gut and obesity

    (19:16) Why obesity is rising

    (25:43) Weight loss vs fat loss vs health

    (25:36) Cutting edge therapies for obesity

    (40:19) A cure for obesity?

    (43:12) The problem with BMI

    (47:21) Why “fat” doesn’t equal “lazy”

    (49:51) The body positivity movement

    Connect with me:

    TikTok: https://www.instagram.com/drkaranrajan

    Instagram: https://www.tiktok.com/@dr.karanr
    Learn more about Dr. Acosta's work: https://phenomixsciences.com/

    For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook

    An OG Podcasts production.

    • 54 min
    Why Medicine Has Failed Women’s Health - Dr Jen Gunter

    Why Medicine Has Failed Women’s Health - Dr Jen Gunter

    “Women’s pain and women’s suffering has just been ignored” -Dr Jen Gunter

    Dr Jen Gunter is an OB/GYN, known for busting myths about women’s health online. She’s the author of Blood, The Menstruation Manifesto and The Vagina Bible.

    In this episode I ask Jen for the truth behind the biggest period myths, from cycle syncing, to menstrual cycles, to the effects of food and why period blood is considered dirty. We also discuss PMS, endometriosis, birth control and more.

    Stay tuned to find out:


    Why we still know so little about female reproductive health
    What to do if you have painful periods - and how much pain is too much
    The truth behind “pill panic” and the demonisation of birth control
    Why exercise is the best medicine
    Whether you should be worried about forever chemicals in tampons
    What we actually know about the vaginal microbiome - are probiotics useless?

    Highlights

    (1:31) The taboos of menstruation

    (3:15) Period myths

    (5:36) Why the lack of medical research and awareness?

    (10:20) The truth about cycle syncing

    (12:21) Can certain foods stop periods?

    (21:53) How to manage PMS symptoms

    (28:47) How women’s pain has been ignored

    (37:10) Endometriosis

    (40:32) The truth about the birth control pill

    (48:07) Toxic tampons and forever chemicals

    (52:24) Probiotics for the vagina

    Connect with me:

    TikTok: https://www.instagram.com/drkaranrajan

    Instagram: https://www.tiktok.com/@dr.karanr

    For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook

    An OG Podcasts production.

    • 1 hr
    The Government Has Lied to You About Psychedelics! Science and Benefits of Hallucinogenic Drugs - Professor David Nutt

    The Government Has Lied to You About Psychedelics! Science and Benefits of Hallucinogenic Drugs - Professor David Nutt

    “The last 55 years of banning psychedelics is the worst censorship of research in the history of the world.” -Professor David Nutt

    Professor David Nutt is THE go-to expert on psychedelics. His charity Drug Science is on a mission to break the stigma around hallucinogenic drugs, and inform the public on the real science behind their effects.

    In this episode I ask David how drugs like magic mushrooms, MDMA, cannabis and Ketamine are able to treat brain disorders, like depression, so effectively - and why we’ve been led to fear these drugs.

    Stay tuned to find out:


    The truth about why psychedelics were banned in the first place
    How safe these drugs are in both a medical and recreational setting
    Whether human evolution was driven, in-part, by psilocybin mushrooms
    About the most recent science and trials
    Myths and misinformation surrounding their use
    How soon we might see the legalisation of psychedelics

    Highlights

    (1:41) 50 years of censorship

    (7:12) Emerging research

    (10:24) Safety of psychedelics

    (12:47) The stoned ape theory

    (19:12) How psychedelics treat depression

    (22:48) When will they be legal?

    (25:38) Physiological changes in the brain during use

    (29:54) Psychedelics versus conventional methods

    (32:47) Recreational use

    (35:47) Microdosing

    (39:06) Enduring benefits of psychedelics

    (42:26) Misinformation

    (44:05) Treating addiction

    (47:13) Future legalisation

    Connect with me:

    TikTok: https://www.instagram.com/drkaranrajan

    Instagram: https://www.tiktok.com/@dr.karanr

    For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook

    An OG Podcasts production.

    • 50 min
    How to Feed Your GUT the RIGHT way - with Dr James Kinross

    How to Feed Your GUT the RIGHT way - with Dr James Kinross

    “It’s not that we’ve lost some microbes, it’s actually that we’ve gained others. And the ones that we’ve gained are causing us harm.”

    Professor James Kinross is a world-leading microbiome expert and bowel cancer surgeon at Imperial College London. He’s also the author of Dark Matter: The New Science of the Microbiome.

    In this episode I ask James about the impact of gut health on all aspects of our bodies, from growth to immune function to brain health and even personality. He also shares advice on the food you should be eating to get your gut health in check - science backed and BS-free.

    Stay tuned to find out:


    How the microbiome is modifiable - you’re not doomed to have poor gut health
    How to figure out whether you have a healthy gut, and what that actually looks like
    Whether probiotics are more hype than health
    The important role of fibre in gut health - and how to get more of it
    Why cooking your own food is so important
    How ultra-processed food changes the microbiome
    The environmental factors you can alter to improve gut health

    Highlights

    (1:35) What is the microbiome?

    (4:05) What impacts the development of the microbiome?

    (9:44) Combating “bad” gut health

    (15:17) Are probiotics any good?

    (22:39) De-Westernising your diet

    (26:46) Problem of ultra-processed food

    (32:48) Impact of the modern environment on gut health

    (42:43) Fibre’s role in gut health

    (49:39) Are artificial sweeteners ok?

    (51:56) Intermittent fasting

    Connect with me:

    TikTok: https://www.instagram.com/drkaranrajan

    Instagram: https://www.tiktok.com/@dr.karanr

    For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook

    An OG Podcasts production.

    • 55 min
    The Science of Naps and How Sleep Boosts Memory and Focus - with Professor Gina Poe

    The Science of Naps and How Sleep Boosts Memory and Focus - with Professor Gina Poe

    “Instead of taking a coffee break, take a nap break!” -Professor Gina Poe

    Professor Gina Poe is a world renowned neuroscientist who runs Poe Lab at UCLA, which investigates the role of sleep in learning and memory consolidation.

    In this episode I ask Gina about the latest science on how to improve and optimise our sleep - with lots of actionable advice.

    Stay tuned to find out:


    How to sleep longer and better
    Why naps are good for you - with strategies on how to nap better
    How a lack of sleep can tank your memory
    How long it should take you to fall asleep
    Whether you should be getting a sleep divorce
    If sleep trackers and wearables help, or hurt - and much more

    Highlights

    (2:49) How sleep impacts memory

    (4:51) Why naps are good for you

    (11:49) Optimal napping strategies

    (14:10) The stages of sleep

    (18:01) How deep sleep affects hormones and memory

    (23:09) The glymphatic system explained

    (27:01) How to tell you’re getting enough sleep

    (29:19) How well do wearables measure sleep?

    (32:35) Should you sleep with your pets?

    (35:46) The sleep divorce

    (37:31) How long should you sleep?

    (39:34) Can you sleep too much?

    (45:32) Strategies for getting more sleep

    (48:09) How quickly should you fall asleep?

    (49:34) Cutting edge sleep research and actionable tips

    Connect with me:

    TikTok: https://www.instagram.com/drkaranrajan

    Instagram: https://www.tiktok.com/@dr.karanr

    For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook


    An OG Podcasts production.

    • 59 min

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