Pharmacology is one of the most challenge topics you will encounter as a healthcare professional, but it can be the most rewarding with a good understanding. Whether you are preparing to be a nurse, physician, physician assistant, pharmacist, dentist, nurse practitioner, pharmacy technician, pharmacologist, or other healthcare professional, this podcast will help you better understand pharmacology. In addition to giving you the basics like mechanism of action, side effects, drug interactions, etc., you will also be exposed to how medications actually impact patients in real life. In the Real Life Pharmacology podcast, Eric Christianson, PharmD shares his real world experiences about how a medication's mechanism of action, pharmacokinetics, adverse effects, and drug interactions can actually impact patients in both a positive and a potentially negative way. Eric Christianson PharmD is the author of the popular clinical pharmacy blog Meded101.com. People who are passionate about nursing, medicine, or pharmacy will find this podcast beneficial in helping them prepare for passing exams. This podcast is for educational purposes only and is not medical advice or intended to be a substitute for medical advice. Please seek advice from your pharmacist or primary care provider if you have questions about medications that you are taking.
On this episode of the Real Life Pharmacology Podcast, I cover topiramate pharmacology.
Topiramate is indicated for migraine prevention, seizures, and weight loss which are the most common uses that I see this medication used for.
Topiramate has carbonic anhydrase activity, so rarely, use of this drug may induce metabolic acidosis.
By far, the most common patient complaint I get with the use of topiramate is that it causes cognitive slowing or impairment.
On this episode I discuss colchicine pharmacology, adverse effects, drug interactions, and pharmacokinetics.
Colchicine ultimately works by reducing the activity of neutrophils that help contribute to pain and inflammation associated with gout.
Colchicine does have some drug interactions with medications and grapefruit juice via CYP3A4.
The most common dose limiting side effect of colchicine is diarrhea.
Colchicine can be used as a potential alternative to NSAIDs or corticosteroids in the management of a gout flare.
Fexofenadine is a 2nd generation antihistamine that is primarily used for allergic rhinitis. I cover fexofenadine pharmacology on this podcast episode.
Fruit juices can actually impair the absorption of fexofenadine and increase the risk of treatment failure.
Fexofenadine is mildly anticholinergic but overall has low to no CNS penetration.
Because fexofenadine has low CNS penetration, the risk for sedation and dizziness is much lower than older antihistamines like diphenhydramine.
On this episode I discuss empagliflozin pharmacology and how this medication lowers blood sugar.
Empagliflozin is associated with an increased risk of genitourinary tract infections.
Be aware that patients who are prone to hypotension, may have an increased risk of this issue with empagliflozin use.
Empagliflozin has cardiovascular and renal function benefits in addition to its blood sugar lowering effects.
On this episode, I discuss rifaximin pharmacology.
Rifaximin is most commonly used in hepatic encephalopathy and C. difficile infection.
Rifaximin systemic absorption is minimal so that is why it is primarily only used for GI conditions.
Drug interactions with rifaximin are fairly minimal compared to its cousin rifampin which has tons of drug interactions.
On this episode of the Real Life Pharmacology Podcast, I discuss naproxen pharmacology.
Naproxen can raise the concentrations of lithium and increase the risk for toxicity.
Compared to most other NSAIDs, naproxen tends to have a lower cardiovascular risk.
Naproxen can contribute to renal insufficiency, GI bleed risk, and CHF exacerbations.
Dr Radhika Vijay(Is Pharmacology Difficult)
Truly a wonderful podcast, a real life inspiration