Cell & Gene: The Podcast

Erin Harris
  • 5.0（2）
  • 生命科学
  • アップデート：隔週

Cell & Gene, the most valuable online resource for delivering in-depth content from authoritative authors and sources to professionals in the CGT sector, introduces Cell & Gene: The Podcast. In each episode, Cell & Gene Chief Editor, Erin Harris, will talk to industry and academic leaders about their current initiatives and how they are moving the sector forward.

  1. 1月29日

    Building Safer CRISPR Medicines for CVD with Scribe Therapeutics' Benjamin Oakes

    We love to hear from our listeners. Send us a message. In episode 121 of Cell & Gene: The Podcast, Host Erin Harris talks to Scribe Therapeutics' CEO and Co-Founder Benjamin Oakes about building next‑generation CRISPR and epigenetic editing tools to move genetic medicine beyond rare disease into common cardiometabolic indications. Oakes shares Scribe’s engineered CasX platform and epigenetic silencers, preclinical data from its various programs, and why exquisite specificity and low-dose LNP delivery are essential to treating patients safely. They also explore Scribe’s partnerships with Sanofi and Lilly, the company’s cardiometabolic-first strategy co-developed with Dr. Jennifer Doudna, and Oakes’ conviction that genetic medicines can fundamentally reshape healthspan and the future of preventive cardiovascular care. Subscribe to the podcast! Apple | Spotify | YouTube Visit my website: Cell & Gene Connect with me on LinkedIn

    30分

  2. 1月15日

    Advancing Off-the-Shelf CRISPR CAR-T Therapies into the Community Setting with Caribou Biosciences' Rachel Haurwitz

    We love to hear from our listeners. Send us a message. Welcome to episode 120 of Cell & Gene: The Podcast. Host Erin Harris is joined by Rachel Haurwitz, CEO of Caribou Biosciences, to discuss the company’s progress in developing CRISPR-edited, off-the-shelf CAR-T therapies for hematologic malignancies. Their conversation centers on Vispacell, Caribou’s allogeneic CD19 CAR-T for second-line large B-cell lymphoma. Haurwitz explains how Caribou has systematically optimized its allogeneic platform using clinical and translational data. They also cover pivotal Phase 3 trial planning, regulatory considerations, and what to expect next from Caribou’s broader pipeline, including its BCMA-targeted program in multiple myeloma. Subscribe to the podcast! Apple | Spotify | YouTube Visit my website: Cell & Gene Connect with me on LinkedIn

    20分

  3. 1月9日

    The Editors' Roundtable: A 2025 Retrospective of the Life Science Industry

    We love to hear from our listeners. Send us a message. We’re sharing this Better Biopharma episode on Cell & Gene: The Podcast because Better Biopharma is a sister show in the Life Science Connect family, and this conversation touches so many of the same challenges, pressures, and big-picture shifts our audience is thinking about right now. CGT doesn’t live in a bubble, and neither do the people building it. So we wanted to bring this wider, cross-industry conversation straight to you. Subscribe to the podcast! Apple | Spotify | YouTube Visit my website: Cell & Gene Connect with me on LinkedIn

    1時間22分

  4. 1月1日

    Developing Itvisma for Broad-Range Treatment of SMA with Novartis' Dr. Norman Putzki

    We love to hear from our listeners. Send us a message. In episode 119 of Cell & Gene The Podcast, Host Erin Harris talks to Dr. Norman Putzki, Global Head Clinical Development, Novartis, about the FDA approval of Itvisma, now the only gene replacement therapy approved for children, adolescents, and adults with spinal muscular atrophy (SMA). Dr. Putzki walks us through the six-year development journey behind the STEER and STRENGTH Phase 3 programs. And we explore what the expanded age-range label means for patients who were previously left behind, why intrathecal, fixed-dose AAV delivery represents a pivotal advance for safety, efficacy, and scalability. He details how the Itvisma program is informing Novartis’ broader gene therapy strategy across neuromuscular and CNS diseases, and more. Subscribe to the podcast! Apple | Spotify | YouTube Visit my website: Cell & Gene Connect with me on LinkedIn

    21分

  5. 2025/12/18

    Turning the Tumor Microenvironment Against Cancer with MGB's Alexander Cryer, Ph.D.

    We love to hear from our listeners. Send us a message. In Episode 118, Host Erin Harris talks to Alexander Cryer, Ph.D., Instructor in Medicine at Mass General Brigham, about a proof of concept strategy that reprograms tumor cells with mRNA lipid nanoparticles to overactivate the cGAS-STING pathway, forcing cancer cells to produce and export large amounts of the innate immune agonist cGAMP to stimulate surrounding immune cells and drive anti-tumor immunity. Dr. Cryer explains the basic biology of cGAS-STING and how his team restored this pathway in tumor cells and leveraged intratumoral LNP delivery to overcome nucleic acid delivery and targeting challenges. He also discusses future directions, the need to move beyond intratumoral administration with more targeted systemic delivery, and the broader concept of turning the tumor’s own abundant cell population and evolutionarily conserved innate immune pathways into therapeutic allies rather than obstacles. Subscribe to the podcast! Apple | Spotify | YouTube Visit my website: Cell & Gene Connect with me on LinkedIn

    16分

  6. 2025/12/04

    Building Patient-Driven Culture and Leadership Resilience in CGT with Paul Perreault

    We love to hear from our listeners. Send us a message. On episode 117, Host Erin Harris welcomes Paul Perreault, Strategic Advisor, Board Member and former CEO of CSL, who shares insights from his decade leading the company through global expansion and the COVID-19 pandemic. Perreault highlights the importance of patient-centered culture, strategic focus, and adaptive leadership for cell and gene therapy innovators. He offers practical advice on building a values-driven culture that connects employees to patients, the importance of focusing on core competencies to attract capital, and the necessity of continuous leadership development, even advocating for mentorship and emotional intelligence as growth drivers in fast-evolving organizations. Subscribe to the podcast! Apple | Spotify | YouTube Visit my website: Cell & Gene Connect with me on LinkedIn

    18分

  7. 2025/11/20

    Treating Inherited Retinal Disorders with Ocugen's Dr. Arun Upadhyay

    We love to hear from our listeners. Send us a message. In episode 116 of Cell & Gene: The Podcast, Host Erin Harris talks to Dr. Arun Upadhyay, Chief Scientific officer, Head of Research and Development at Ocugen to discuss how the company’s modifier gene therapy platform is redefining treatment possibilities for inherited retinal diseases such as retinitis pigmentosa, Stargardt disease, and geographic atrophy. Dr. Upadhyay explains how Ocugen’s gene-agnostic approach differs from traditional single-gene therapies by targeting shared disease pathways to preserve photoreceptors and slow vision loss across diverse genetic mutations. He also shares key lessons learned from advancing OCU400, the first modifier gene therapy to receive a broad FDA indication for retinitis pigmentosa, including challenges in clinical trial design, endpoint selection, and manufacturing scalability. Subscribe to the podcast! Apple | Spotify | YouTube Visit my website: Cell & Gene Connect with me on LinkedIn

    27分

  8. 2025/11/06

    Advancing Hematology and Cell Therapy Innovation with AstraZeneca's Aliya Omer

    We love to hear from our listeners. Send us a message. Episode 115 of Cell & Gene: The Podcast features Host Erin Harris' talk with Aliya Omer, Vice President and Global Head of Hematology and Cell Therapy at AstraZeneca. Omer shares valuable insights from her rich experience leading cell therapy development across multiple top companies. She highlights the critical importance of collaboration by breaking down silos across research, manufacturing, regulatory, and commercial teams to deliver innovative therapies efficiently. She also discusses AZ’s diverse and ambitious cell therapy portfolio, encompassing autologous CAR-T, TCR-T, in vivo gene therapies, and regulatory T-cell therapies. She candidly addresses current challenges in manufacturing scalability, patient access, and healthcare system readiness and describes how AZ is prioritizing fast manufacturing platforms and ecosystem-wide partnerships to surmount these hurdles.  Subscribe to the podcast! Apple | Spotify | YouTube Visit my website: Cell & Gene Connect with me on LinkedIn

    34分
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5
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番組について

Cell & Gene, the most valuable online resource for delivering in-depth content from authoritative authors and sources to professionals in the CGT sector, introduces Cell & Gene: The Podcast. In each episode, Cell & Gene Chief Editor, Erin Harris, will talk to industry and academic leaders about their current initiatives and how they are moving the sector forward.

情報

  • クリエイター
    Erin Harris
  • 配信期間
    21年 - 26年
  • エピソード
    127
  • 制限指定
    不適切な内容を含まない
  • Copyright
    © 2026 Cell & Gene: The Podcast
  • 番組のWebサイト
    Cell & Gene: The Podcast

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