Diabetes Connections | Type 1 Diabetes Stacey Simms

It’s In the News! A look at the top diabetes stories and headlines happening now. Top stories this week: Dexcom goes Direct to Watch in the US, Abbott gets FDA okay for its OTC CGM, new study about metformin during pregnancy, an update on semaglutides, JDRF changes its name, and more!
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Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com)
Omnipod - Simplify Life
Learn about Dexcom 
Edgepark Medical Supplies
Check out VIVI Cap to protect your insulin from extreme temperatures
Learn more about AG1 from Athletic Greens 
Drive research that matters through the T1D Exchange
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Reach out with questions or comments: info@diabetes-connections.com
Episode transcription with links:
 
Hello and welcome to Diabetes Connections In the News! I’m Stacey Simms and every other Friday I bring you a short episode with the top diabetes stories and headlines happening now.
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In the news is brought to you by Edgepark simplify your diabetes journey with Edgepark
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Our top story this week – some CGM news…
Dexcom announces Direct to Watch is here in the US.
From the release: Using its own dedicated Bluetooth connection, Dexcom G7 sends glucose information and personalized alerts right to a user’s Apple Watch. Dexcom G7 is the only CGM system that can display glucose on multiple devices simultaneously and independently, including on a smartphone, smart watch, receiver or connected automated insulin delivery system.‡
Apple products are built with strong privacy protections and users have control over their data in the Health app.
(If you like to keep track of these things, we are just over 7 years since the official announcement this was going to happen)
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FDA approves Abbot’s over-the-counter continuous glucose monitoring system. It’s called Lingo and comes a couple of months after Dexcom won clearance for its Stelo over-the-counter CGM. Abbott has been selling Lingo in the UK as more of a lifestyle device – not aimed at people with diabetes. They call it a consumer biowearable designed to help people make decisions about their overall health and wellness; Lingo is not intended for use in diagnosis, treatment or management of a disease or medical condition. No word yet on exactly what kind of app they’ll launch here in the US or if it will be marketed toward people with diabetes like the Libre currently is.. just as an OTC option. While it seems like the same hardware, the company has not confirmed that.
https://www.drugdeliverybusiness.com/abbott-wins-fda-clearance-for-its-lingo-otc-glucose-monitor/
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New study looking at the use of continuous glucose monitors (CGMs by rural children and adolescents living with type 1 diabetes.
Previous studies examining the use of CGMs by children relied on prescription records to identify use of these devices, but just because someone is prescribed a CGM does not mean that they use one; barriers such as cost can stand in the way. this study instead identified use of these devices according to billing codes for the interpretation of CGM readings by the provider.
The results unearthed a sizeable disparity. Those living in rural areas were significantly less likely to use a CGM than those in urban areas, even after adjusting for sex, race or ethnicity and insurance type. Specifically, compared with youth living in urban areas, the use of CGMs was 31% lower for children and adolescents living in small rural towns, and 49% lower for those living in isolat

We’ve been hearing about smart insulin for a long time. This refers to an insulin that would react to glucose levels and adjust by itself with no external device, like a CGM, needed. You’d inject and let the insulin do the work.
I’m talking to Sensulin CEO Mike Moradi about where their version of this amazing sounding technology stands, his family connections that really feeds his passion here, and what has to happen to get glucose-responsive insulin into the hands of people who could benefit.  
This podcast is not intended as medical advice. If you have those kinds of questions, please contact your health care provider.
Find out more about Moms' Night Out - registration is open for Denver and Philadelphia!
Please visit our Sponsors & Partners - they help make the show possible!
Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com)
Omnipod - Simplify Life
Learn about Dexcom 
Edgepark Medical Supplies
Check out VIVI Cap to protect your insulin from extreme temperatures
Learn more about AG1 from Athletic Greens 
Drive research that matters through the T1D Exchange
The best way to keep up with Stacey and the show is by signing up for our weekly newsletter:
Sign up for our newsletter here
Here's where to find us:
Facebook (Group)
Facebook (Page)
Instagram
Twitter
Check out Stacey's books!
Learn more about everything at our home page www.diabetes-connections.com 
Reach out with questions or comments: info@diabetes-connections.com

Disney very recently made some changes to their Disability Access Services program – often referred to as a DAS pass at Disney World and Disney Land. We’re going to talk about why this happened, what it means for you, and what else is going on at Disney.
Note: this interview was taped BEFORE the changes took place.
More about Len Testa's Touring Plans here
More about the DAS changes here
We’re also spending some time talking about a new service for doctors called Glucosepath and about a new surprising study about cortisol and diabetes. I’ll also explain how these two guests can talk about all of these issues..
Len Testa is co host of the fabulous Disney Dish podcast and the creator of Touring Plans the app and service of The Unofficial Guides to Walt Disney World, Disneyland and Disney Cruise Line. Testa is all about the math of theme parks – his guides are there to maximize the magic as he says – to make your waits shorter and save money – and it’s all based on calculations from his team.
He teamed up with endocrinologist Dr. Bradly Eilerman to create GlucosePATH which uses computer science and clinical data to evaluate every possible treatment option, using data from the patient, FDA, and peer-reviewed journals, in just a few seconds.
Dr. Eilerman also talks about the Catalyst study which looks at people with type 2 diabetes and measures cortisol. 
This podcast is not intended as medical advice. If you have those kinds of questions, please contact your health care provider.
Find out more about Moms' Night Out - registration is open for Denver!
Please visit our Sponsors & Partners - they help make the show possible!
Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com)
Omnipod - Simplify Life
Learn about Dexcom 
Edgepark Medical Supplies
Check out VIVI Cap to protect your insulin from extreme temperatures
Learn more about AG1 from Athletic Greens 
Drive research that matters through the T1D Exchange
The best way to keep up with Stacey and the show is by signing up for our weekly newsletter:
Sign up for our newsletter here
Here's where to find us:
Facebook (Group)
Facebook (Page)
Instagram
Twitter
Check out Stacey's books!
Learn more about everything at our home page www.diabetes-connections.com 
Reach out with questions or comments: info@diabetes-connections.com

This week, creating a bihormonal pump – using insulin and glucagon in one device - has been the goal of Beta Bionics since before the company even had that name. Now that they’ve launched the insulin-only version of their iLet, we’re getting an update on the dual chambered version. The big news is a new agreement with Xeris to supply that shelf-stable glucagon. But there are still a lot of questions. We’re talking to the CEOs of both companies.
This podcast is not intended as medical advice. If you have those kinds of questions, please contact your health care provider.
Find out more about Moms' Night Out - registration is open for Denver!
Please visit our Sponsors & Partners - they help make the show possible!
Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com)
Omnipod - Simplify Life
Learn about Dexcom 
Edgepark Medical Supplies
Check out VIVI Cap to protect your insulin from extreme temperatures
Learn more about AG1 from Athletic Greens 
Drive research that matters through the T1D Exchange
The best way to keep up with Stacey and the show is by signing up for our weekly newsletter:
Sign up for our newsletter here
Here's where to find us:
Facebook (Group)
Facebook (Page)
Instagram
Twitter
Check out Stacey's books!
Learn more about everything at our home page www.diabetes-connections.com 
Reach out with questions or comments: info@diabetes-connections.com

This week, talking with one of the lawyers bringing a class-action lawsuit against the insulin companies.. a lawsuit that has been inching forward since 2017. It was set to be settled for 500-million dollars and a four year price cap, but then judge said no.  Attorney Steve Berman will talk about that last minute surprise, why he’s still going forward, and  what he needs now from the diabetes community.
This podcast is not intended as medical advice. If you have those kinds of questions, please contact your health care provider.
My guest is Attorney Steven Berman from the firm Hagens (Haagens like Haagen Daas) Berman. Steve co-founded Hagens Berman in 1993 after his prior firm refused a fast food e coli case. That turned out to be the famous case against Jack in the Box, which resulted in a class action settlement and changed many food safety laws. He’s also been involved in cases against Big Tobacco and, as you’ll hear, other medical pricing lawsuits.  
Learn more about the case and fill out the form to see if you're entitled to compensation here: https://www.hbsslaw.com/cases/insulin-overpricing#block-form-block-destination
Find out more about Moms' Night Out - registration is open for Denver!
Please visit our Sponsors & Partners - they help make the show possible!
Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com)
Omnipod - Simplify Life
Learn about Dexcom 
Edgepark Medical Supplies
Check out VIVI Cap to protect your insulin from extreme temperatures
Learn more about AG1 from Athletic Greens 
Drive research that matters through the T1D Exchange
The best way to keep up with Stacey and the show is by signing up for our weekly newsletter:
Sign up for our newsletter here
Here's where to find us:
Facebook (Group)
Facebook (Page)
Instagram
Twitter
Check out Stacey's books!
Learn more about everything at our home page www.diabetes-connections.com 
Reach out with questions or comments: info@diabetes-connections.com

It’s In the News! A look at the top diabetes stories and headlines happening now. Top stories this week: more older adults are being diagnosed with type 1 and people with T1D are living longer, Eversense gets iCGM designation, new drug to prevent low BG is being tested, Tandem diabetes app recall, and more!
Find out more about Moms' Night Out 
Please visit our Sponsors & Partners - they help make the show possible!
Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com)
Omnipod - Simplify Life
Learn about Dexcom 
Edgepark Medical Supplies
Check out VIVI Cap to protect your insulin from extreme temperatures
Learn more about AG1 from Athletic Greens 
Drive research that matters through the T1D Exchange
The best way to keep up with Stacey and the show is by signing up for our weekly newsletter:
Sign up for our newsletter here
Here's where to find us:
Facebook (Group)
Facebook (Page)
Instagram
Twitter
Check out Stacey's books!
Learn more about everything at our home page www.diabetes-connections.com 
Reach out with questions or comments: info@diabetes-connections.com
Episode transcription with links:
Hello and welcome to Diabetes Connections In the News! I’m Stacey Simms and every other Friday I bring you a short episode with the top diabetes stories and headlines happening now.
XX
In the news is brought to you by Edgepark simplify your diabetes journey with Edgepark
XX
Type 1 diabetes is increasingly affecting older adults in the US, with prevalence rates peaking in those aged 45 to 64, according to recent research published in JAMA.1
The life expectancy for people with T1D has increased over the last 15 years, which has led to increased prevalence among older adults.2 The CDC currently estimates that approximately 1.8 million people in the US have T1D.3
The study utilized data from the 2019 to 2022 cycles of the National Health Interview Survey (NHIS), representative of the noninstitutionalized US population. The study included over 141,000 participants (110,283 adults and 30,708 youths).
The increasing prevalence of T1D in older adults suggests that further research is needed to develop treatment guidelines that include strategies to optimize treatment in older adults living with T1D. Current clinical practices often extrapolate from data on younger populations or those with type 2 diabetes, which may not be entirely appropriate for older adults with specific needs in terms of cardiovascular and glycemic management.
 
https://www.ajmc.com/view/t1d-prevalence-rising-among-us-adults-study-finds
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Pancreatic cancer research may have implications for diabetes. These reserachres were looking at an enzyme called focal adhesion kinase (FAK). During the trials, quote - "The pancreas looked weird, almost like it was trying to regenerate after an injury," Even weirder, a cluster of cells in the pancreas were expressing both insulin and amylase. In normal mice and humans, the blood sugar-regulating hormone insulin is produced by beta cells, while amylase, a digestive enzyme, is manufactured by different cells. The functions of acinar and beta-cells are very distinct, so it didn't make sense that the cluster of cells looked like a combination of the two.
Esni and his team had in fact stumbled upon this holy grail. In a new Nature Communications paper, the researchers show that a FAK-inhibiting drug, which has been studied in cancer treatment, converted acinar cells into acinar-derived insulin-producing (ADIP) cells and helped regulate blood glucose in diabetic mice and a single non-human primate.
The findings suggest that FAK inhibitors could be a new avenue as a replacement for insulin therapy in diabetic patients.
With the eventual hope of launching a clinical trial to test FAK inhibitor in diabetes patients, Esni and his team are now planning long-term experiments in mice to look at the durati