GW Integrative Medicine GW Integrative Medicine

Proton pump inhibitors, or PPIs, are a class of popular drugs that reduce the amount of acid produced in the stomach. They are often the first-line treatment for conditions related to acid, such as esophagitis, non-erosive reflux disease, and peptic ulcer disease.

We talk about PPIs and dementia with Misha Kogan, MD, ABIOM, RCST, medical director of the GW Center of Integrative Medicine and associate professor of Medicine here at GW. Studies show that people who take proton pump inhibitors (PPIs) for more than four years and are 45 or older have a 33% higher risk of developing dementia than those who have never taken PPIs.

An expert on neurodegenerative diseases, Dr. Kogan completed the Geriatric Fellowship at GW. He is the chief editor of the first definitive textbook on Integrative Medicine and aging, “Integrative Geriatric Medicine,” part of Andrew Weil Integrative Medicine Library series.

Dr. Kogan is also on the faculty of the GW Institute for Brain Health and Dementias; associate director of the Geriatrics Fellowship Program at GW; and founder and director othe George Washington University Integrative Geriatrics Fellowship Track.

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Related Content

Institute for Brain Health and Dementia
https://brainhealth.gwu.edu/

Choudhury A, Jena A, Jearth V, et al. Vitamin B12 deficiency and use of proton pump inhibitors: a systematic review and meta-analysis. Expert Rev Gastroenterol Hepatol. 2023;17(5):479-487. doi:10.1080/17474124.2023.2204229
https://pubmed.ncbi.nlm.nih.gov/37060552/

Gommers LMM, Hoenderop JGJ, de Baaij JHF. Mechanisms of proton pump inhibitor-induced hypomagnesemia. Acta Physiol (Oxf). 2022;235(4):e13846. doi:10.1111/apha.13846
https://pubmed.ncbi.nlm.nih.gov/35652564/

Geng T, Chen JX, Zhou YF, et al. Proton Pump Inhibitor Use and Risks of Cardiovascular Disease and Mortality in Patients With Type 2 Diabetes. J Clin Endocrinol Metab. 2023;108(6):e216-e222. doi:10.1210/clinem/dgac750
https://pubmed.ncbi.nlm.nih.gov/36573284/

Liu W, Wang J, Wang M, Wang M, Liu M. Association of proton pump inhibitor use with risk of kidney stones: an analysis of cross-sectional data from the US National Health and Nutrition Examination Survey (2007-2018). BMJ Open. 2023;13(10):e075136. Published 2023 Oct 16. doi:10.1136/bmjopen-2023-075136
https://pubmed.ncbi.nlm.nih.gov/37844987/

Gao S, Song W, Lin T, et al. Prolonged Use of Proton Pump Inhibitors, but Not Histamine-2 Receptor Antagonists, Is Associated With Lower Bone Mineral Density in Males Aged Over 70. Front Med (Lausanne). 2021;8:725359. Published 2021 Aug 23. doi:10.3389/fmed.2021.725359
https://pubmed.ncbi.nlm.nih.gov/34497815/

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Transcript

https://bit.ly/3V1BoJT

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This podcast features the song “Follow Your Dreams” (freemusicarchive.org/music/Scott_Ho…ur_Dreams_1918) by Scott Holmes, available under a Creative Commons Attribution-Noncommercial (01https://creativecommons.org/licenses/by-nc/4.0/) license.

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Disclaimer: The content and information shared in GW Integrative Medicine is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in GW Integrative Medicine represent the opinions of the host(s) and their guest(s). For medical advice, diagnosis, and/or treatment, please consult a medical professional.

Today on the pod we are going to talk about the science behind nutritional neuroscience with Stephen Fleming, PhD. This scientific discipline studies the effects various components of the diet such as minerals, vitamins, protein, carbohydrates, fats, dietary supplements, synthetic hormones, and food additives have on neurochemistry, neurobiology, behavior, and cognition, according to the journal Nutritional Neuroscience.

An expert on nutrition and cognitive development, Dr. Fleming is also the co-founder and CEO of Traverse Science, Inc., a company that helps researchers at global nutrition organizations take a visual and evidence-based approach to scientific substantiation.

He found his roots first in psychology (B.S) and later as a neuroscientist (PhD) at the University of Illinois at Urbana-Champaign. His mission is to create tools, teams, and frameworks that enable others to cut through misinformation and data overload to understand the science.

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Transcript
(Coming)

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This podcast features the song “Follow Your Dreams” (freemusicarchive.org/music/Scott_Ho…ur_Dreams_1918) by Scott Holmes, available under a Creative Commons Attribution-Noncommercial (01https://creativecommons.org/licenses/by-nc/4.0/) license.

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Disclaimer: The content and information shared in GW Integrative Medicine is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in GW Integrative Medicine represent the opinions of the host(s) and their guest(s). For medical advice, diagnosis, and/or treatment, please consult a medical professional.

Today on the pod we talk about cancer survivorship with Sanna Ali, MSN, CRNP, an Oncology nurse practitioner (NP), cancer survivorship researcher and advocate, and PhD student at the School of Nursing at George Washington University. She currently practices at the GW Center for Integrative Medicine.

In her role as an NP, she saw first-hand the multifaceted, complex issues that burden cancer survivors. She decided to pursue her PhD to develop the research skills needed for knowledge generation and scientific discovery that will improve the quality of life and outcomes for cancer survivors. She has presented her PhD-related work both locally and nationally. She received a Sigma Theta Tau International, Phi Epsilon Chapter Small Grant for 2023-2024 to support her project, “Perspectives and attitudes of oncology professionals related to cancer survivorship: A qualitative case study.”

NP Ali is the Maryland State Liaison for the American Association of Nurse Practitioners (AANP) where she works to advance and support the NP profession at the state and national levels. She is also a member of the National Coalition for Cancer Survivorship (NCCS) Champions program for clinicians and researchers interested in improving care for cancer survivors.

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Related Links

NP Ali's bio
https://bit.ly/48UcGPz

National Coalition for Cancer Survivorship article on NP Ali
https://bit.ly/497OI3u

National Coalition for Cancer Survivorship
https://bit.ly/3TFSP22

The National Cancer Institute’s Office of Cancer Complementary and Alternative Medicine
https://cam.cancer.gov/

American Society of Clinical Oncology's Integrative Oncology blog posts
https://bit.ly/4913b15

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Transcript
https://bit.ly/3JoA2mz

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This podcast features the song “Follow Your Dreams” (freemusicarchive.org/music/Scott_Ho…ur_Dreams_1918) by Scott Holmes, available under a Creative Commons Attribution-Noncommercial (01https://creativecommons.org/licenses/by-nc/4.0/) license.

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Disclaimer: The content and information shared in GW Integrative Medicine is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in GW Integrative Medicine represent the opinions of the host(s) and their guest(s). For medical advice, diagnosis, and/or treatment, please consult a medical professional.

Today on the pod we talk about C-15:0 Essential Fatty Acid with Dr. Stephanie Venn-WatsonDVM, MPH. Dr. Venn-Watson is the CEO and co-founder of Seraphina Therapeutics, Inc. in San Diego, California. She and her husband, Eric Venn-Watson, MD, made the groundbreaking discovery of C15:0.

Also known as pentadecanoic acid, C15:0 is an essential fatty acid that has largely disappeared from the modern Western diet. Certain kinds of fatty acids can actually slow aging-related breakdown in our cells. And C15:0 is one of them.

The Drs. Venn-Watson are bringing it to the market as a food fortifier and nutritional supplement called fatty15.

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Related Links

Discover C15: A Nutritional Discovery 90 Years in the Making
www.DiscoverC15.com

Fatty15
www.Fatty15.com

Dr. Venn-Watson’s TEDx Talk: Save the dolphins. Save the world
https://bit.ly/48Vuz0t

Broader and safer clinically-relevant activities of pentadecanoic acid compared to omega-3: Evaluation of an emerging essential fatty acid across twelve primary human cell-based disease systems
https://bit.ly/434UOjn

Pentadecanoylcarnitine is a newly discovered endocannabinoid with pleiotropic activities relevant to supporting physical and mental health
https://bit.ly/3wBxIF3

Dairy Fat Intake, Plasma C15:0 and Plasma Iso-C17:0 are inversely associated with Liver Fat in Children
https://bit.ly/49CuSON

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Transcript
https://bit.ly/3JoA2mz

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This podcast features the song “Follow Your Dreams” (freemusicarchive.org/music/Scott_Ho…ur_Dreams_1918) by Scott Holmes, available under a Creative Commons Attribution-Noncommercial (01https://creativecommons.org/licenses/by-nc/4.0/) license.

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Disclaimer: The content and information shared in GW Integrative Medicine is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in GW Integrative Medicine represent the opinions of the host(s) and their guest(s). For medical advice, diagnosis, and/or treatment, please consult a medical professional.

We get sciency with the GW School of Medicine & Health Sciences' Anil Bajnath, MD, MBA, IFMCP, ABAARM, MIFHI, an expert on Precision Medicine, aka Personalized Medicine. (Sciency is a word—it's in the OED.) This episode was originally published May 31, 2020. Dr. Bajnath is the CEO and Founder of The Institute for Human Optimization Precision Medicine Research Group and an Adjunct Assistant Professor in the GW Integrative Medicine Programs at the university.

The NIH describes Precision Medicine as "an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person."

Dr. Bajnath is board-certified in Family Medicine and Integrative Medicine. Throughout the span of a decade, he has cultivated extensive first-hand experience in Precision, Integrative, Functional and Genomic Medicine.

He is also the author of "The Longevity Equation: The Step-By-Step Blueprint to Hack Your Genes, Optimize Your Health, And Master the Art of Existence."

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Related Content

Dr. Bajnath's website
https://anilbajnath.com/

Dr. Bajnath's book: "The Longevity Equation: The Step-By-Step Blueprint to Hack Your Genes, Optimize Your Health, And Master the Art of Existence" https://longevityequation.net/

NIH: The Promise of Precision Medicine
https://www.nih.gov/about-nih/what-we-do/nih-turning-discovery-into-health/promise-precision-medicine

Sung Symposium: Next Generation Health
www.youtube.com/watch?v=Xlf3jhJNB…&feature=emb_logo

CDC: Precision health: Improving health for each of us and all of us
https://www.cdc.gov/genomics/about/precision_med.htm

Who Will Benefit From Precision Medicine
www.ucsf.edu/magazine/benefit-precision-medicine

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Transcript

www.linkedin.com/pulse/transcript…lth/?published=t

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This podcast features the song “Follow Your Dreams” (freemusicarchive.org/music/Scott_Ho…ur_Dreams_1918) by Scott Holmes, available under a Creative Commons Attribution-Noncommercial (01https://creativecommons.org/licenses/by-nc/4.0/) license.

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Disclaimer: The content and information shared in GW Integrative Medicine is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in GW Integrative Medicine represent the opinions of the host(s) and their guest(s). For medical advice, diagnosis, and/or treatment, please consult a medical professional.

Today we discuss evidence-based approaches that use food and the gut microbiome to promote health and treat disease with Christopher Damman, MD, MA, a board-certified gastroenterologist and internist at the Digestive Health Center at the University of Washington Medical Center and CMO, Scientific Medical & Scientific Officer at Uplifting Results Labs.

Dr. Damman is a physician scientist with a particular interest in the microbiome and functional foods. Earlier in 2023, he gave a talk on the clinical application of the evidence base for dietary and microbial interventions to support well-being at our 6th Annual Sung Symposium: The Gut, Microbes, & Well-being.

Dr. Damman has a particular interest in the microbiome & functional foods, and he explores these themes as Editor-In-Chief at Gut Bites MD.

He’s also a clinical associate professor of Medicine at the University of Washington and entrepreneur with 20+ years of experience across the private, philanthropic, and academic sectors.

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Related Links

Dr. Dammen's Bio & Research Page
https://bit.ly/3G2f76u

Gut Bites MD
https://gutbites.org/

Hangry bacteria in your gut microbiome are linked to chronic disease—feeding them these nutrients could lead to a healthier body
https://bit.ly/3unqMuc

VIDEOS | 2023 Sung Symposium: The Gut, Microbes, & Well-being
https://bit.ly/SungVideos

Uplifting Results Labs
https://bit.ly/46pOjaV

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Transcript
bit.ly/45OtWE6

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This podcast features the song “Follow Your Dreams” (freemusicarchive.org/music/Scott_Ho…ur_Dreams_1918) by Scott Holmes, available under a Creative Commons Attribution-Noncommercial (01https://creativecommons.org/licenses/by-nc/4.0/) license.

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Disclaimer: The content and information shared in GW Integrative Medicine is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in GW Integrative Medicine represent the opinions of the host(s) and their guest(s). For medical advice, diagnosis, and/or treatment, please consult a medical professional.