Medscape InDiscussion: Heart Failure Medscape

Drs Michelle Kittleson, Anu Lala-Trindade, and Rob Mentz kick off the new season of Medscape's heart failure podcast series by describing how they leverage social media for positive change.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/997314). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Heart Failure https://emedicine.medscape.com/article/163062-overview
Journal of Cardiac Failure https://onlinejcf.com/
Diwali https://www.britannica.com/topic/Diwali-Hindu-festival
Heart Failure Society of America (HFSA) https://hfsa.org/
2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines https://pubmed.ncbi.nlm.nih.gov/35363499/
Medscape App https://medscape.onelink.me/U6kk/dgka5w4j

Drs Michelle Kittleson and Evan Kransdorf talk about when to test, how genetic testing should be interpreted, and what to do with the results.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/997316). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Validating an Idiopathic Dilated Cardiomyopathy Diagnosis Using Cardiovascular Magnetic Resonance: The Dilated Cardiomyopathy Precision Medicine Study https://pubmed.ncbi.nlm.nih.gov/35240856/
Prevalence and Cumulative Risk of Familial Idiopathic Dilated Cardiomyopathy https://pubmed.ncbi.nlm.nih.gov/35103767
Family Heart Talk https://dcmproject.com/family-heart-talk/
Effectiveness of the Family Heart Talk Communication Tool in Improving Family Member Screening for Dilated Cardiomyopathy: Results of a Randomized Trial https://pubmed.ncbi.nlm.nih.gov/36938756/
Rare Variant Genetics and Dilated Cardiomyopathy Severity: The DCM Precision Medicine Study https://pubmed.ncbi.nlm.nih.gov/37641966/
Standards and Guidelines for the Interpretation of Sequence Variants: A Joint Consensus Recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology https://pubmed.ncbi.nlm.nih.gov/25741868/
Implications of Genetic Testing in Dilated Cardiomyopathy https://pubmed.ncbi.nlm.nih.gov/32880476/
Clinical Risk Score to Predict Pathogenic Genotypes in Patients With Dilated Cardiomyopathy https://pubmed.ncbi.nlm.nih.gov/36109106/
Screening for Dilated Cardiomyopathy in At-Risk First-Degree Relatives https://pubmed.ncbi.nlm.nih.gov/37225358/

Drs Michelle Kittleson and Richard Cheng do a deep dive into cardiac sarcoidosis, discussing everything from diagnosis to management.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/997317). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Debating the Definition and Incidence of Isolated Cardiac Sarcoidosis https://pubmed.ncbi.nlm.nih.gov/32972559/
Cardiac Sarcoidosis — State of the Art Review https://pubmed.ncbi.nlm.nih.gov/26885492/
HRS Expert Consensus Statement on the Diagnosis and Management of Arrhythmias Associated With Cardiac Sarcoidosis https://pubmed.ncbi.nlm.nih.gov/24819193/
Abstract 11937: Genetic Cardiomyopathies Misdiagnosed as Isolated Cardiac Sarcoidosis: High-Yield Results of a Systematic Screening Strategy https://www.ahajournals.org/doi/10.1161/circ.146.suppl_1.11937
Cardiac Sarcoidosis Randomized Trial (CHASM-CS-RCT) https://classic.clinicaltrials.gov/ct2/show/NCT03593759
Rituximab for the Treatment of Refractory Cardiac Sarcoidosis: A Single-Center Experience https://pubmed.ncbi.nlm.nih.gov/34320381/

Drs Michelle Kittleson and Ilan Wittstein unravel the complexities of stress cardiomyopathy, discussing the challenges in diagnosis and insights into management strategies.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/997319). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Takotsubo Cardiomyopathy: Review of Broken Heart Syndrome https://pubmed.ncbi.nlm.nih.gov/32039951
Takotsubo Cardiomyopathy Following Cardiac Surgery https://pubmed.ncbi.nlm.nih.gov/26661572/
Stress Cardiomyopathy in Critical Care: A Case Series of 109 Patients https://pubmed.ncbi.nlm.nih.gov/36331975/
Immune Checkpoint Inhibitor-Associated Myocarditis: Manifestations and Mechanisms https://pubmed.ncbi.nlm.nih.gov/33645548/
Acute Stress Cardiomyopathy: Heart of Pheochromocytoma https://pubmed.ncbi.nlm.nih.gov/32988608/
Takotsubo Cardiomyopathy: Pathophysiology and Role of Cardiac Biomarkers in Differential Diagnosis https://pubmed.ncbi.nlm.nih.gov/29081904/
Short- and Long-Term Incidence of Thromboembolic Events in Takotsubo Syndrome as Compared With Acute Coronary Syndrome https://pubmed.ncbi.nlm.nih.gov/30987433/
Clinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy https://pubmed.ncbi.nlm.nih.gov/26332547/
Withdrawal of Pharmacological Treatment for Heart Failure in Patients With Recovered Dilated Cardiomyopathy (TRED-HF): An Open-Label, Pilot, Randomised Trial https://pubmed.ncbi.nlm.nih.gov/30429050/
Comparison of Complications and In-Hospital Mortality in Takotsubo (Apical Ballooning/Stress) Cardiomyopathy Versus Acute Myocardial Infarction https://pubmed.ncbi.nlm.nih.gov/32762963/
Gender Differences in Patients With Takotsubo Cardiomyopathy: Multi-Center Registry From Tokyo CCU Network https://pubmed.ncbi.nlm.nih.gov/26317750/

Drs Michelle Kittleson and Ronald Oudiz dive into everything cardiologists need to know about the diagnosis and treatment of pulmonary hypertension.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/997320). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Heart Failure https://emedicine.medscape.com/article/163062-overview
Pulmonary Arterial Hypertension https://emedicine.medscape.com/article/303098-overview
Cardiac Catheterization in Pulmonary Hypertension: Doing It Right, With a Catheter on the Left https://pubmed.ncbi.nlm.nih.gov/33224785/
How to Initiate and Uptitrate GDMT in Heart Failure: Practical Stepwise Approach to Optimization of GDMT https://pubmed.ncbi.nlm.nih.gov/36456074/
Phosphodiesterase Inhibitors https://www.ncbi.nlm.nih.gov/books/NBK559276/
Cardiovascular Biology of Prostanoids and Drug Discovery https://pubmed.ncbi.nlm.nih.gov/32295420/
Soluble Guanylate Cyclase as an Emerging Therapeutic Target in Cardiopulmonary Disease https://pubmed.ncbi.nlm.nih.gov/21606405/
Pulmonary Hypertension Association https://phassociation.org/

Drs Michelle Kittleson and Jennifer Cowger discuss navigating the future of heart failure care through durable mechanical circulatory support, including patient selection, outcomes, and upcoming advances.
Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/997321. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Heart Failure https://emedicine.medscape.com/article/163062-overview
The Future of Durable Mechanical Circulatory Support: Emerging Technological Innovations and Considerations to Enable Evolution of the Field https://pubmed.ncbi.nlm.nih.gov/38431185/
Impact of 2018 Allocation System Change on Outcomes in Patients With Durable Left Ventricular Assist Device as Bridge to Transplantation: A UNOS Registry Analysis https://pubmed.ncbi.nlm.nih.gov/36973093/
OPTN Policy 6: Allocation of Hearts and Heart-Lungs https://unos.org/resources/heart-lung-toolkits/
The Impella Device: Historical Background, Clinical Applications and Future Directions https://pubmed.ncbi.nlm.nih.gov/31384109/#full-view-affiliation-1
INTERMACS (Interagency Registry for Mechanically Assisted Circulatory Support) Profiling Identifies Ambulatory Patients at High Risk on Medical Therapy After Hospitalizations for Heart Failure https://pubmed.ncbi.nlm.nih.gov/27834198/
Response Shift in Patient-Reported Outcomes: Definition, Theory, and a Revised Model https://pubmed.ncbi.nlm.nih.gov/33909187/
Physiology and Clinical Utility of HeartMate Pump Parameters https://pubmed.ncbi.nlm.nih.gov/34980564/
2023 Gordon Research Seminar on Assisted Circulation (GRS): Translating Mechanical Circulatory Support from Bench to Bedside to Global Implementation https://www.grc.org/assisted-circulation-grs-conference/2023/