61 episodes

Each 15-minute podcast will provide an overview of the issue’s contents and relevant news in the field of basic/translational cardiovascular biology followed by an in-depth discussion of a featured article. This discussion will pull opinions from the podcast hosts, editorial team, research leaders and authors – both the corresponding authors as well as the trainee(s). We will provide lively discussions that give the listener a behind the scenes look at how science gets done and the implications of these fascinating discoveries.

Discover CircRes Cynthia St. Hilaire, PhD & Milka Koupenova, PhD

    • Science

Each 15-minute podcast will provide an overview of the issue’s contents and relevant news in the field of basic/translational cardiovascular biology followed by an in-depth discussion of a featured article. This discussion will pull opinions from the podcast hosts, editorial team, research leaders and authors – both the corresponding authors as well as the trainee(s). We will provide lively discussions that give the listener a behind the scenes look at how science gets done and the implications of these fascinating discoveries.

    June 2024 Discover CircRes

    June 2024 Discover CircRes

    This month on Episode 61 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the June 7th and June 21st issues of Circulation Research. This Episode also includes a discussion with Dr Chris O'Callaghan and Jiahao Jiang from the University of Oxford about their study, A Novel Macrophage Subpopulation Conveys Increased Genetic Risk of Coronary Artery Disease.
    Article highlights:
    Compendium on Interface Between Cardioimmunology, Myocardial Health, and Disease
    Zafeiropoulo, et al. Splenic Ultrasound Improves Pulmonary Hypertension
    Roman, et al. MICU3 Enhances Mitochondrial Ca2+ Uptake

    • 27 min
    May 2024 Discover CircRes

    May 2024 Discover CircRes

    This month on Episode 60 of Discover CircRes, host Cindy St. Hilaire highlights original research articles featured in the May 10 and May 24th issues of Circulation Research. This Episode also includes a discussion with Dr Sophie Astrof and Dr AnnJosette Ramirez from Rutgers University about their study, Buffering Mechanism in Aortic Arch Artery Formation and Congenital Heart Disease.
    Article highlights:
    Tamiato, et al. Pericyte RGS5 in Cardiac Aging
    Zifkos, et al. PTP1B and Venous Thromboinflammation
    Ma, et al. NR4A3 in Vascular Calcification
    Sultan, et al. VEGF-B Induced Coronary Endothelial Cell Lineage

    • 36 min
    April 2024 Discover CircRes

    April 2024 Discover CircRes

    This month on Episode 59 of Discover CircRes, host Cindy St. Hilaire highlights original research articles featured in the April 12 and April 26th issues of Circulation Research. This Episode also includes a discussion with Dr Craig Morrell and Chen Li from University of Rochester about their study, Thrombocytopenia Independently Leads to Changes in Monocyte Immune Function.
    Article highlights:
    Arkelius, et al. LOX-1 and MMP-9 Inhibition Improves Stroke Outcomes
    Cruz, et al. C122Y Disrupts Kir2.1-PIP2 Interaction in ATS1
    Blaustein, et al. Environmental Impacts on Cardiovascular Health and Biology: An Overview

    • 31 min
    March 2024 Discover CircRes

    March 2024 Discover CircRes

    This month on Episode 58 of Discover CircRes, host Cynthia St. Hilaire highlights three original research articles featured in the March 1 and March 15th issues of Circulation Research. This Episode also includes a discussion with Drs Frank Faraci, Tami Martino, and Martin Young about their contributions to the Compendium on Circadian Mechanisms in Cardiovascular and Cerebrovascular Disease.
    Article highlights:
    Yan, et al. GCN2 in Ponatinib-Induced Cardiotoxicity
    Wang, et al. Activating v-ATPase Ameliorates Cardiac Cardiomyopathy

    • 40 min
    February 2024 Discover CircRes

    February 2024 Discover CircRes

    This month on Episode 57 of Discover CircRes, host Cynthia St. Hilaire highlights three original research articles featured in the February 2nd and February 19th issues of Circulation Research. This Episode also includes a discussion with Dr Kathryn Howe and Dr Sneha Raju from University of Toronto, about their manuscript titled Directional Endothelial Communication by Polarized Extracellular Vesicle Release.
     
    Article highlights:
    Ren, et al. ZBTB20 Regulates Cardiac Contractility
    Faleeva, et al. Sox9 Regulates Vascular Extracellular Matrix Aging
    Bai, et al. PKA Is Critical for Cardiac Growth
    Wang, et al. Indole-3-Propionic Acid Protects Against HFpEF

    • 35 min
    January 2024 Discover CircRes

    January 2024 Discover CircRes

    This month on Episode 56 of Discover CircRes, host Cynthia St. Hilaire highlights three original research articles featured in the January 5th and January 19th issues of Circulation Research. This Episode also includes a discussion with Dr Julie Freed and Gopika Senthilkumar from the Medical College of Wisconsin about their study, Necessary Role of Ceramides in the Human Microvascular Endothelium During Health and Disease.
     
    Article highlights:
    He, et al. T Cell LGMN Deficiency Prevents Hypertension
    Salyer, et al. TnI-Y26 Phosphorylation Improves Relaxation
    Jacob, et al. MFN2 in Megakaryocyte and Platelet Function

    • 30 min

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