Life Science Success Don Davis PhD, MBA

In this episode of the Life Science Success Podcast, host Don Davis, PhD, MBA, interviews Dr. William Chou of Passage Bio. Dr. Chou discusses his transition from a practicing physician to a leader in biotechnology, reflects on the profound patient relationships he misses, and shares insights into Passage Bio's work on gene therapy for neurodegenerative diseases like Frontotemporal Dementia (FTD). They delve into the progress of their Phase 1/2 clinical study, the urgency of developing treatments for genetic mutations, and the potential impact on patients and their families.
 
Learn about the most recent developments and how Passage Bio is working to give those suffering from these life-threatening conditions hope.
 
00:00 Welcome and Introduction
00:25 William's Journey into Life Sciences
01:30 The Emotional Impact of Leaving Clinical Practice
02:31 Overview of Passage Bio
02:52 Understanding Frontotemporal Dementia (FTD)
06:38 Current Progress and Future Prospects
10:04 The Urgency and Hope for FTD Treatments
11:37 Goals and Closing Remarks

In this episode of the Life Science Success Podcast, Don Davis PhD, MBA interviews Igor Fisch, founder of NewBiologix. Igor shares his journey from academia to entrepreneurship, highlighting his success with Selexis, a company he sold in 2017 that specialized in monoclonal antibodies. He discusses the challenges of gene therapy, specifically the high costs, and NewBiologix's innovative approach to making gene therapy more affordable. Igor also provides insights into the industry's future, emphasizing the significance of stable production platforms for viral particles.
00:00 Introduction and Welcome
00:15 Igor's Journey into Life Sciences
00:37 The Success of Selexis
00:56 Transition to Gene Therapy
03:32 Challenges in Gene Therapy
03:50 The Importance of Stable Platforms
05:11 The Role of Biotech Startups
05:57 Balancing Science and Business
06:51 Networking at BIO Conference
08:14 Future Vision for New Biologics
09:21 Conclusion and Farewell

In this episode of the Life Science Success Podcast, Dean Petkanas, co-founder of Kannalife Sciences, is interviewed at the Bio International Convention in San Diego. Dean shares his journey from investment banking in the 80s to founding Kannalife Sciences in 2009. He discusses the company's focus on developing cannabinoid-based drugs, specifically targeting chemotherapy-induced peripheral neuropathy. The conversation covers the challenges and opportunities in cannabinoid drug development, the importance of targeting specific types of pain, and the current state and future prospects of Kannalife Sciences. Dean also highlights the significance of partnering and collaboration in advancing novel therapeutics.
 
 
 
00:00 Welcome to the Life Science Success Podcast
00:20 Dean's Journey into Life Sciences
01:04 The Evolution of Kannalife Sciences
02:18 Challenges and Opportunities in Cannabinoid-Based Drugs
03:06 Understanding Pain and Neuropathy
06:08 Investment Insights and Market Trends
07:40 Kannalife Sciences's Current Focus and Future Prospects
10:02 The Importance of Partnering at Bio
11:02 Closing Remarks and Future Meetings

 

In this episode of the Life Science Success Podcast, host Don interviews Sean Rothwell, CEO of Evoke Nano, about the company's groundbreaking work in developing EBQ218, a revolutionary nanoparticle-based pulmonary therapeutic. They discuss the efficacy of EBQ218 in treating cystic fibrosis and its potential as a broad-spectrum antibiotic against drug-resistant superbugs. Sean shares insights into the company's journey, their upcoming clinical trials, and the broader impact of their work on patient outcomes in the healthcare landscape. Tune in to learn how Evoke Bio is poised to make a significant difference in combating infectious diseases and improving lives.
 
 
00:00 Welcome and Introduction
00:09 First Impressions of BIO Conference
00:37 Sean's Background and Journey into Life Sciences
01:42 The Science Behind Evoke Nano
02:28 EBQ218: A Revolutionary Pulmonary Therapeutic
04:16 Challenges and Future Pathways
05:24 Investment and Partnership Opportunities
06:42 Broader Applications and Future Vision
08:16 Addressing Drug Resistance and Regulatory Pathways
18:48 Conclusion and Final Thoughts

This is the second part of the interview where, with Maruiano, we will discuss more of the technology and development for Elem Biotech.  
 
In this episode of the Life Science Success Podcast, Don Davis discusses the BIO conference and the future of biomedical research with Mauriano Vázquez. They delve into the significance of networking events, the evolution of computing capabilities, advanced simulation codes, and the potential applications of AI and quantum computing in life sciences. Mauriano shares his unique journey from Argentina to becoming a physicist specializing in computational mechanics, and how his work in cardiac electrophysiology can significantly impact patient care. The conversation wraps up with insights into the future use of virtual and augmented reality in medical applications.
 
 
00:00 Introduction and Conference Impressions
02:37 Mariano's Background and Journey into Life Sciences
06:22 Applications of Simulation Technology
10:48 Evolution of Computing Capabilities
13:37 Future of AI and Quantum Computing
14:41 Virtual Reality in Medical Applications
19:40 Conclusion and Final Thoughts

There are two parts of this interview, in the first session, I dive into Elem and what the company is doing with Christopher Morton.  
 
In this exciting episode of Life Science Discussed Podcast, host Don Davis welcomes Christopher Morton, CEO of Elem Biotech, to talk about the groundbreaking work of virtual human twins in drug and medical device testing. Morton, an aeronautical engineer turned biotech innovator, discusses Elem's platform that allows pharmaceutical companies, medtechs, and CROs to test new therapeutics using virtual human models instead of animal models. They delve into how this approach, distinct from AI-based methods, focuses on mechanistic modeling using MRIs and CT scans to replicate human physiological functions. Morton explains how Elem Biotech's solutions help in precision medicine, clinical trial design, and reducing animal trials, supported by supercomputing power and cloud technology. Tune in to discover how virtual human models are poised to transform life sciences and medical testing.
 
00:00 Introduction and Welcome
00:43 Christopher Morton's Background
01:57 Introduction to Elem Biotech
02:45 Mechanistic Approach vs. AI Models
03:47 Precision Medicine and Virtual Human Twins
08:58 Supercomputing and Technological Infrastructure
13:07 Applications in Pharma and Medical Devices
21:07 Challenges and Future Directions
25:59 Conclusion and Final Thoughts