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For many researchers, modern science has become about getting results rather than asking questions. Results mean publications, and publications mean more funding.
However, results are not the objective of the scientific method, which involves proposing an answer to a question, designing experiments to determine whether the proposed answer is true or false, and objectively interpreting the results.
This episode of Listen In explores the definition of the scientific method and how to apply it to your research.
Get a handle on the scientific method with a clear definition, and learn how to apply it to your research using real-life examples of the scientific method in action.
You will come away from this tutorial with increased confidence in the rigor of your research and the fundamental knowledge to design scientifically sound experiments.
Watch the full presentation here: https://events.bitesizebio.com/confirmation-bias-and-the-1/join
Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/

For many researchers, modern science has become about getting results rather than asking questions. Results mean publications, and publications mean more funding.
However, results are not the objective of the scientific method, which involves proposing an answer to a question, designing experiments to determine whether the proposed answer is true or false, and objectively interpreting the results.
Nonetheless, the results-focused attitude to doing science is widespread, and it comes with a huge drawback—it encourages confirmation bias—making us prone to searching for evidence and interpreting findings to support proposed answers we believe to be true.
This episode of Listen In explores what confirmation bias is and how to avoid it.
Learn why confirmation bias is so common, how it creeps into our thinking, and how it degrades the quality of our experimental designs and findings.
You will come away from this tutorial with the tools needed to defend against confirmation bias, challenge what you believe, and reorient yourself from a results-focused outlook to a method-focused one.
Watch the full presentation here: https://events.bitesizebio.com/confirmation-bias-and-the/
Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/

Volume electron microscopy or volume EM (vEM) was named one of Nature's Technologies to Watch in 2023. The new Thermo Scientific Hydra Bio PFIB integrates advanced cryo-TEM lamella preparation to volume EM workflows.
In this episode of Listen In, see how the new Thermo Scientific Hydra Bio Plasma-Focused Ion Beam (PFIB) extends cryo technology to volume EM and enables the acquisition of high-resolution 3D data through automated serial milling and imaging of frozen-hydrated specimens.
Cryo Auto Slice & View enables the acquisition of high-resolution 3D data through automated serial milling and imaging for striking new insights into a range of frozen-hydrated specimens prepared by high-pressure freezing or plunge freezing.
The choice of four different plasma ion species offers advantages for imaging cryo- and resin-embedded samples. The Hydra Bio also features the Spin Mill Bio Method, an exclusive technique for large-area planar milling that yields similar-sized imaging areas as microtome slicing. Plus, see how Hydra Bio PFIB combines field-proven and new techniques to enable cryo and room temperature applications.
Watch the full presentation here: https://events.bitesizebio.com/cryo-tomography-to-volume-em/room
Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/

In this episode of Listen In, see how emerging and global challenges of conducting ethical animal research have led to the 12Rs Framework to guide humane experimental techniques in animal studies and other research areas.
The Principles of Humane Experimental Technique, the 3Rs (Replacement, Refinement, and Reduction), have been the mainstay of humane research involving animals for over fifty years.
However, it is becoming increasingly apparent that to enable high-quality ethical and humane science involving animals, other ethical constructs and issues, for example, research culture, reproducibility, reliability, and responsibility, must also be considered.
The 12Rs Framework brings these different constructs together in a single visual framework. Furthermore, it applies to all areas of scientific research, not just research involving animals.
Watch the full presentation here: https://events.bitesizebio.com/the-12rs-framework-enabling/join
Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/

In this episode of Listen In, learn more about how the convergence of AI technology and scientific discovery can revolutionize our understanding of biology and disease.
Generating insights into tissue microenvironments is crucial to our understanding of normal and abnormal tissue development, such as during cancer progression.
Spatial biology methods using microscopy and multiplexing techniques have allowed researchers to bring together protein expression profiles and spatial information to dive into the complex biology needed for these insights. However, image analysis of these datasets, especially with high numbers of protein markers and/or large numbers of cells, remains a challenge.
Artificial Intelligence (AI) image analysis has significantly progressed through innovations in deep learning, segmentation, and detection, making it a powerful tool for researchers.
Hear about the latest release of Aivia image analysis software, including AI tools, to help you tackle this challenge in your large 2D multiplexed image datasets.
Watch the full presentation here: https://microscopyfocus.com/elevate-your-research-with-spatial-insights/
Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/

Glycosylation is a prevalent modification of proteins known to play diverse roles across a wide range of biological processes.
While glycoproteins are widely recognized as key molecular features involved in human health and disease, the analysis of protein glycosylation has historically been hampered by a lack of efficient and simple methods to characterize the analytically challenging glycan structures. Examples include structures exhibiting extensive heterogeneity and subtle isomeric features such as linkage and topological differences.
In this episode of Listen In, Dr. Thaysen-Andersen discusses opportunities and challenges in the burgeoning field of analytical glycoscience.
See the current landscape of glycobiology, learn about innovative analytical methods for N- and O-linked glycosylation profiling from biological specimens, and explore how advances in glycoanalytics enable new insights into human glycobiology.
MilliporeSigma is the U.S. and Canada Life Science business of Merck KGaA, Darmstadt, Germany.
Watch the full presentation here: https://events.bitesizebio.com/unleash-new-biological-insights/join
Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/