Everyday Wellness Everyday Wellness: Cynthia Thurlow, NP

I am thrilled to present the last class of our Lipid Masterclass series today with the esteemed Dr. Thomas Dayspring. Dr. Dayspring is board-certified in internal medicine and clinical lipidology and is a fellow of the American College of Physicians and the National Lipid Association. 
Today, we round things out by diving into medications for lipid abnormalities and discussing lipid physiology, with Dr. Dayspring shedding light on insulin resistance and statins and cautioning against statin use for those predisposed to diabetes or insulin resistance. He also explains why LDL particle size is not worth testing and discusses ways to identify specific laboratory abnormalities. 
Be sure to stay tuned for the AMA session to follow, where Dr. Dayspring will answer listeners’ questions. 
It has been a privilege engaging with Dr. Dayspring throughout this masterclass series. I know you will have learned a lot from it!

IN THIS EPISODE YOU WILL LEARN:
· The lack of research and consistency in addressing the needs of women in various stages of life
· Dr. Dayspring discusses the use of bile acid sequestrants for lowering LDL cholesterol
· Dr. Dayspring discusses the history of bile acid sequestrant use, explaining why their use is limited
· How bempedoic acid and statins lower LDL cholesterol
· Potential contraindications for bempedoic acid
· The benefits and risks of using fibrates to reduce heart attacks
· Dr. Dayspring explains why fibrates work best for genetic hypertriglyceridemia
· Why reducing ApoB is essential for atherosclerosis patients, especially for high-risk patients
· Dr. Dayspring explains why small LDL particles are dangerous
· The ideal ApoB level for those who have no heart disease and are not diabetic 

Bio:
Thomas Dayspring MD is a Fellow of both the American College of Physicians and the National Lipid Association and is certified in internal medicine and clinical lipidology. After practicing in New Jersey for 37 years, in 2012, he moved to Virginia to serve as an educational director for a nonprofit cardiovascular foundation until mid-2019 as a Chief Academic Advisor for two major CV laboratories. Since then, he has served as a virtual cardiovascular/lipidology educator. Career-wise, he has given over 4000 domestic (in all 50 states) and several international lectures, including over 600 CME programs on atherothrombosis, lipids/lipoproteins (and their treatment), vascular biology, biomarker testing, and women’s cardiovascular issues. He has authored several manuscripts and lipid textbook chapters and performed several podcasts. For several years, he was an Associate Editor of the Journal of Clinical Lipidology. He received the 2011 National Lipid Association’s Presidents Award for services to clinical lipidology and the 2023 Foundation of NLA Clinician/Educator Award. He has over 34K followers on his educational Twitter (X) feed (@Drlipid). He has Gold Heart Member status as a professional member of the American Heart Association, and he serves as a Social Media Ambassador for the European Atherosclerosis Society and the National Lipid Association.

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I am delighted to reconnect with Dr. Anurag Singh today, the Chief Medical Officer at Timeline Nutrition. He joined me once before on Episode 268. 
I invited Dr. Singh back to discuss the latest research on GLP-1 agonists like Wegovy, Semaglutide, and Ozempic, which are gaining significant traction with projected sales exceeding $100 billion by 2030, potentially affecting 9% of the US population.
In our conversation, we explore the contributors to our metabolic health crisis by looking at the research surrounding GLP-1 agonists, the physiology of GLP-1 peptides, and the influencing elements Dr. Singh refers to as the trifecta. We dive into the loss of muscle mass and strength, sarcopenia, and frailty associated with these drugs, and Dr. Singh shares his concerns about their impact on bone health, the gut microbiome, and their use in younger patients. We also get into lifestyle measures, mitochondrial health, hallmarks of aging, Akkermansia, and the importance of advocacy and patient empowerment. 
Today’s compelling and invaluable discussion with Dr. Anurag Singh highlights crucial insights into GLP-1 agonists and their broader health implications. I know it will provide significant value for our listeners.

IN THIS EPISODE YOU WILL LEARN:

Dr. Singh breaks down what GLP-1 agonist drugs are and how they work.

How our modern-day lifestyles contribute to poor metabolic health

The benefits and side-effects of using GLP-1 agonist treatments for improving metabolic health

Why strength training is essential for preventing muscle loss and frailty in middle-aged women

What are the potential long-term effects of SARMs on muscle mass and health?

Why dietary counseling is essential for those taking GLP-1 agonist drugs

The benefits of supplements for boosting mitochondrial health 

Dr. Singh discusses a research study on combining lithium with GLP-1 agonists to improve the muscle quality of those with muscle-wasting conditions.

Why akkermansia is essential for GLP production

 
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Timeline

Mitopure

Email Dr. Singh: asingh@amazentis.com 



Previous Episode Mentioned
Ep. 268: Understanding the Biology of Aging with Evolved Supplementation and Nutrition, featuring Dr. Anurag Singh

Today, I am delighted to reconnect with two previous guests, Dr. Darren Candow.
Dr. Candow is a distinguished professor and an internationally renowned researcher on creatine monohydrate, nutrition, and physical activity who joined me before on Episode 301, where we spoke about creatine. 
We are doing an AMA session today, delving into various themes surrounding creatine, from debunking outdated RDA recommendations to exploring the synergies between strength training and creatine efficacy. We look into the cognitive benefits of creatine, exploring how it interacts with caffeine and its implications for bone health, hydration, anabolic resistance, and metabolic health. 
I trust you will find today's AMA session as enlightening and enriching as I did while recording it.

IN THIS EPISODE YOU WILL LEARN:

The safety and efficacy of creatine as a supplement

How creatine increases muscle mass and reduces protein catabolism

The benefits of combining creatine with protein 

Is it better to take creatine before or after a workout?

How creatine supplementation may improve brain performance and mental clarity

Why exercise is essential for those who want to experience the benefits of creatine for maintaining their bone health

The benefits of resistance-band workouts for post-menopausal women

Are there any age-related limits for creatine supplementation?


Bio: Dr. Darren Candow
Dr. Darren Candow, PhD, CSEP-CEP, is Professor and Director of the Aging Muscle and Bone Health Laboratory in the Faculty of Kinesiology and Health Studies at the University of Regina, Canada. The overall objectives of Dr. Candow’s research program are to develop effective lifestyle interventions involving nutrition (primarily creatine monohydrate) and physical activity (resistance training), which have practical and clinical relevance for improving musculoskeletal aging and reducing the risk of falls and fractures. Dr. Candow has published over 120 peer-refereed journal manuscripts, supervised over 20 MSc and PhD students, and received research funding from the Canadian Institutes of Health Research, Canada Foundation for Innovation, the Saskatchewan Health Research Foundation, the National Institute of Health, and the Nutricia Research Foundation. In addition, Dr. Candow serves on the editorial review boards for the Journal of the International Society of Sports Nutrition, Nutrients, and Frontiers.

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Previous Episode Mentioned:
Ep. 301 Creatine: The Best Supplement for Better Bones & Brain Health with Darren Candow, PhD, CSEP-CEP

I am honored to have Dr. Carolyn Dean joining me today.
Dr. Dean is a medical doctor, naturopath, and best-selling author. She has dedicated more than 50 years to integrating the science of medicine with the gifts of nature to help her patients feel better, boost their energy, and take control of their health.
Today, our conversation centers on The Flexner Report and its influence on modern medicine and the essential role of magnesium in over 80% of metabolic functions. We dive into why we are so magnesium-depleted and common disorders associated with low magnesium levels, and we explore the effects of magnesium on bone health and the microbiome and the synergistic properties of various forms of magnesium and other micronutrients. 
I am confident you will find today’s discussion with Dr. Carolyn Dean as enjoyable as it is enlightening.

IN THIS EPISODE YOU WILL LEARN:

How the Flexner Report has impacted allopathic, functional, and integrative approaches to health and wellness

Why is magnesium so poorly understood?

How to get your magnesium accurately tested

How our modern-day lifestyles are contributing to the current magnesium deficiency epidemic 

Dr. Dean shares her formula for hydration 

The potential side effects of allopathic medications and how they impact our health

Why magnesium is essential for aging women

The relationship between magnesium and bone health

The benefits of magnesium supplementation

The complex relationship between magnesium and other minerals

Dr. Dean talks about Magnesium Threonate and explains how all magnesium compounds can ultimately reach the brain.


Bio:
Carolyn Dean, MD, ND, is a medical doctor, naturopath, and best-selling author. She has spent 50+ years committed to applying the science of medicine and the gifts of nature to help people feel better, find more energy, and take control of their personal health. Dr. Dean follows the 2017 revision of 2004's best-selling book The Magnesium Miracle® with her newest revision Magnesium: The Missing Link to Total Health®.

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Magnesium: The Missing Link to Total Health by Dr. Carolyn Dean is available on Amazon 

Recommended Publication
Magnesium in the Central Nervous System

I am delighted to reconnect with Dr. Dave Rabin today. He last joined me for Episode 91 in April of 2020.
Dr. Rabin is a board-certified psychiatrist and neuroscientist. He is the Co-founder and CMO at Apollo Neuroscience, the first scientifically validated wearable system to improve heart rate variability, focus, and relaxation, and helps attain meditative states. He is also Co-founder and Executive Director of the Board of Medicine and a psychedelic clinical researcher, currently evaluating the mechanism of psychedelic-assisted psychotherapy and treatment-resistant illness.
Today, we examine the value of touch and sensory techniques, discussing the distinctions between sympathetic and parasympathetic vagal tone in the autonomic nervous system, changes in sex hormones during perimenopause and menopause, and how that impacts sympathetic dominance, the development of stress responses, and the concept of stress leading to personal growth. We explore the influence of the vagus nerve on systemic health, explaining what HRV is and how it can demonstrate bodily coherence, and we also dive into wearable technologies like Apollo, the disruption of psychedelic interventions, and the impact of trauma on physical and mental well-being. 
I am confident that you will find today’s engaging discussion with Dr. Dave Rabin eye-opening and enlightening.
IN THIS EPISODE YOU WILL LEARN:

How touch helps us connect, bond, and support our autonomic nervous system

How finding balance between the parasympathetic and sympathetic nervous systems can help us manage stress and anxiety

Techniques for quickly restoring balance to the nervous system

Why women experience more anxiety, depression, and heart arrhythmias during perimenopause

How breathing techniques can improve heart rate variability 

The significance of HRV metrics for understanding physical and mental health

How the Apollo device activates a healing response within the body

The potential of MDMA and other psychedelics hold for trauma healing


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Connect with Dr. Dave Rabin

On his website


Apollo

Instagram

Twitter (X)

The Psychedelic Report Podcast

Your Brain Explained Podcast


Previous Episode Mentioned
Ep. 91 – How To Listen To Your Body and DE-STRESS During COVID-19 – with Dr. David Rabin

I am thrilled to connect with my friend and colleague, Dr. Tony Youn today. 
Dr. Youn is a nationally recognized board-certified plastic surgeon and the author of many best-selling books. He has a massive social media presence and hosts the widely acclaimed podcast The Holistic Plastic Surgery Show.
In our conversation today, we dive into Dr. Youn’s new book, Younger for Life, and he offers valuable insights on skin health and overall well-being. We explore the aging process and address oxidative-free radical damage, chronic inflammation, autophagy, and the impact of processed foods. We also get into helpful supplements for skin support, examine the concept of greenwashing, and discuss sunscreen, exfoliation, in-office treatments, breast implant illness, and the power of lifestyle choices.
Stay tuned for more!

IN THIS EPISODE YOU WILL LEARN:

How to avoid aging too quickly through nutrition and lifestyle changes

How sugar and seed oils impact skin aging

The benefits of collagen supplements for healthier skin 

Hormonal changes that affect the metabolism and skin health after menopause

The importance of screening the ingredients in skincare products

How chemical sunscreens differ from physical sunblocks

Using Retinol for anti-aging and skin health

Non-invasive fat reduction treatments and their potential risks

Dr. Youn discusses breast implant illness

What you need to look out for when using Botox


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Connect with Dr. Anthony Youn

On his website



Youn Beauty  

On Instagram, YouTube, TikTok, Facebook, and Twitter


The Holistic Plastic Surgery Show

Buy a copy of Younger for Life 

Bookshop.Org