Your discovery point for scientific and medical research on cannabis.
#22 Antidepressant Effects of Ketamine with Dr. Lisa Monteggia
Dr. Lisa Monteggia, a neuroscientist and Professor of Pharmacology at Vanderbilt University, shares her groundbreaking research on the antidepressant effects of ketamine. In this episode, we discuss how ketamine affects the brain—she reveals the neural mechanisms it induces in the brain, how it works differently than other antidepressant medicines (like SSRIs), and why dosing is so critical. We discuss Ketamine’s ability to induce plasticity in the brain and how that could revolutionize treatment for refractory depression.
#21 Octopuses, MDMA, and Social Reward Learning with Dr. Gul Dölen
Dr. Gul Dölen, a neuroscientist and Associate Professor at the Brain Science Institute at Johns Hopkins School of Medicine, discusses MDMA’s potential to reopen the critical period for social reward learning in animal research models. She shares how MDMA affects the brain’s capacity to process new social information and how long this enhanced neuroplasticity lingers. She also shares what happens to octopuses (typically anti-social creatures), when they are observed on MDMA, and the importance of pursuing science for curiosity’s sake.
#20 Does Cannabis Use Affect Athletic Performance? with Dr. Jonny Lisano
Dr. Jonny Lisano, an exercise physiologist who specializes in the field of cannabis and exercise science, reveals patterns he has observed in his research between cannabis use and exercise performance. We discuss how cannabis use affects (and doesn’t affect) anaerobic fitness, pulmonary health, and the presence of C-Reactive proteins in your blood. We also discuss whether cannabis should be considered legitimate medicine for NFL players and why using cannabis before exercise might help you feel a “Runner’s High” a little sooner.
#19 The Three Subtypes of High-THC Cannabis with Dr. Nick Jikomes
Nick Jikomes, PhD, neuroscientist and the Director of Science & Innovation at Leafly, shares what he has learned analyzing crowd-sourced data from patients/consumers on cannabis strains and products. Dr. Jikomes reveals that there are only a handful of chemical subtypes among high-THC strains and he shares the three primary chemical profiles you might find at a dispensary. We also discuss the association between certain terpenes and cannabinoids, like Terpinolene & CBG.
#18 Psychedelics to Catalyze Connection with Dr. Julie Holland
Psychiatrist Dr. Julie Holland, MD, reveals how psychedelic medicines, like cannabis, MDMA, and psilocybin can help us feel more connected to ourselves, our community, and the natural world. We discuss what happens to our brains when we take psychedelics, why we are hardwired for connection, and the difference between the recreational and medical models of using these substances.
#17 Dr. Peter Grinspoon on Opiate Addiction and Recovery
Dr. Peter Grinspoon, MD shares his recovery story after facing an addiction to prescription painkillers. We discuss some of the issues with current addiction therapy and rehabilitation programs and how we can improve the experience of recovery and reduce dependency on opiates by incorporating cannabis into addiction therapy.