Dhru Purohit Show Dhru Purohit

This episode is brought to you by Birch Living, Cozy Earth, and Lumebox. 
The conversation about longevity inevitably includes the goal of aging with strength and vitality. At 70 years old, today’s guest brings a wealth of experience and insight into health and well-being. He discusses his shift from focusing on demanding endurance activities to sustainable activities that bring him joy. Prepare to be inspired.
Today on The Dhru Purohit Show, Dhru interviews Mark Sisson to hear his insights on longevity and wellness. After more than thirty years in the fitness industry, Mark explains why he has shifted his focus away from supplements to prioritize mobility, metabolic flexibility, and intuitive eating. He also tells the story behind his creation of minimalist shoes and discusses the detrimental effects of modern sneakers on our feet. Dhru and Mark explore the lessons from Blue Zones and how we can intentionally integrate them into our lives to create a joyful existence.
Mark Sisson is a prominent health and fitness expert, author, and entrepreneur known for pioneering the "Primal" movement. Transitioning from athlete to advocate, he founded Mark's Daily Apple, a blog promoting ancestral health principles, including a high-fat, low-carb diet, functional fitness, and overall wellness. Sisson has authored several influential books, including The Primal Blueprint. In 2015, he launched Primal Kitchen, a line of health-conscious food products that quickly gained popularity for its clean, real-food ingredients. Sisson's work has inspired millions to rethink conventional health wisdom and adopt a more holistic approach to well-being, emphasizing the importance of natural movement, stress management, and nutrient-dense foods. 

In this episode, Dhru and Mark dive into (audio version / Apple Subscriber version):

Why Mark has doubled down on supplementing with collagen (00:00:32 / 00:00:32)

Why Mark deprioritized supplements in his life (10:50 / 8:08) 

Optimal protein (20:00 / 17:15)

Dhru’s personal journey on prioritizing protein and building muscle (29:30 / 25:00)

Mark’s view on what to eat and develop metabolic flexibility (42:40 / 37:10)

Being flexible and not feeling deprived (45:50 / 41:20)

Eating intuitively (51:20 / 46:45)

Walking and optimal dose (44:30 / 49:00)

Modern shoes and how they harm your feet (1:01:30 / 57:00)

The power of stretching (1:10:45 / 1:06:15)

Lessons from Blue Zones that we can translate into our lives (1:14:30 / 1:10:00)

Being transparent about test results when offering advice (1:20:20 / 1:15:40)

Creating a life of joy (1:33:20 / 1:28:50)


Also mentioned in this episode:

Mark’s Daily Apple

Peluva Shoes 

Study on the impact of bed rest 


For more on Mark, follow him on Instagram, Twitter, or his website. 

To get 20% off your Birch Living mattress plus two free eco-rest pillows, head over to birchliving.com/dhru today.

Right now, get 30% off your Cozy Earth sheets. Just head over to cozyearth.com/dhru and use code DHRUP.

Lumebox is offering my community $260 off their FDA-approved portable Red Light device! That's over 40% off! Go to thelumebox.com/dhru and get your Red Light device.
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This episode is brought to you by LMNT, Lifeforce, and AquaTru.

Cardiovascular disease is increasingly prevalent among South Asians, particularly Indian immigrants. The rise of this health issue, especially among younger Indian Americans, is attributed not only to lifestyle factors but also to cultural beliefs surrounding success and a lack of emphasis on prioritizing health. Today’s guest joins us in dissecting these nuances and encouraging individuals to focus on longevity.

Today on The Dhru Purohit Show, Dhru sits down with Dr. Manickam Palaniappan (Dr. Pal) to discuss the dangers of belly fat and visceral fat, particularly among the South Asian population. Dr. Pal explains why South Asians should be cautious even if they have a "normal" lipid profile but aren't considered obese by traditional standards. He also shares his personal journey, which led to a deeper understanding of true health and the challenges immigrants face in achieving success. Dr. Pal provides top tips on optimal fiber and protein intake and identifies the risk factors for heart disease.

Dr. Manickam Palaniappan is a renowned gastroenterologist recognized for his expertise in digestive health and innovative treatment approaches. Currently serving as a leading gastroenterologist at a major medical center, Dr. Palaniappan is highly respected for his skill in managing complex gastrointestinal disorders, including inflammatory bowel disease, liver diseases, and colorectal cancer. His commitment to patient care is matched by his involvement in cutting-edge research, contributing to numerous peer-reviewed publications that have advanced the field of gastroenterology.

In this episode, Dhru and Dr. Pal dive into (audio version / Apple Subscriber version):

Why belly fat is dangerous (00:00:02 / 00:00:02)

Dr. Pal’s journey in discovering why visceral fat was dangerous (3:22 / 3:22)

What is visceral fat (12:15 / 8:54)

Genetics versus environment (17: 20 / 14:00) 

The importance of gut health in reclaiming your health (21:20 / 17:00)

The role of excess insulin, flours, and seed oils (28:51 / 24:00)

Risk Factors that impact heart disease (44:50 / 40:00)

Fiber and optimal amounts (49:00 / 44:16)

Prioritizing protein (51:50 / 47:00) 

Body composition test (54:00 / 49:50)

Five points of Gut Man challenge (1:00:00 / 54:30)

Tracking your calorie intake as an assessment tool (1:04:00 / 58:00)

Top mistakes people make in their journey (1:16 50 / 1:12:00)

Final Thoughts (1:22:00 / 1:1:17:00) 


Also mentioned in this episode:
Study on the increase in skeletal muscle index amounts to a reduction in insulin resistance and risk of type 2 diabetes risk

For more on Dr. Pal, follow him on YouTube, Instagram, TikTok, Twitter, or his website. 

Right now, LMNT is offering my listeners a free sample pack with any purchase. Head over to DrinkLMNT.com/dhru today.

Right now, you can save $250 on your first diagnostic and get personalized suggestions. Optimize your longevity and track your progress; go to mylifeforce.com/dhru! 

AquaTru is a countertop reverse osmosis purifier with a four-stage filtration system that removes 15x more contaminants than the bestselling water filters out there. Go to dhrupurohit.com/filter/ and get $100 off when you try AquaTru for yourself.
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This episode is brought to you by BiOptimizers, Momentous, and Lumebox. 

The debate around vegetable oils is heating up in the wellness community. While some tout them as a heart-healthy swap for saturated fats, others argue they pose more significant risks to our health than previously believed. Our guest today contends that vegetable oils are wreaking havoc on our well-being and are a primary culprit behind numerous chronic diseases.

Today on The Dhru Purohit Show, Dhru sits down with Dr. Cate Shanahan to discuss seed oils and how they have overtaken our diet. Dr. Shanahan shares the top eight oils destroying our health and their hidden sources. She also shares the process used to make these oils and the research on the impact of oxidative stress. Dhru and Dr. Shanahan also discuss why there is so much confusion about these oils and how to reduce overall exposure to these oils. 

Dr. Cate Shanahan is a Cornell-trained physician-scientist whose works have inspired movements involving bone broth, live-culture ferments, and seed oil-free business empires. Together with NBA legend Gary Vitti, she created the LA Lakers PRO Nutrition program, which wide elite championship teams worldwide have emulated. Dedicated to her field, she runs a telehealth practice and a health education website. In her upcoming book Dark Calories, Dr. Shanahan provides shocking evidence that vegetable oils are a public health disaster, wreaking havoc on our bodies by depleting antioxidants and causing the cellular damage that underlies virtually all chronic diseases.

In this episode, Dhru and Dr. Shanahan dive into (audio version / Apple Subscriber version):

The hateful eight oils that are destroying health (00:00:03 / 00:00:03)

What are the sources of these oils (8:20 / 4:42) 

Are french fries comparable to cigarettes (10:20 / 6:50)

Underestimating the harm seed oils cause (15:50 / 12:15)

Why consumers are confused (28:10 / 23:30)

How oxidative stress caused by oils  (32:10: / 27:00)

What diseases these oil accelerate (39:20 / 33:58)

Why many believe that vegetable oils aren’t harmful (42:40 / 37:25)

Are vegetable oils inflammatory and how to test for damage (45:25 / 40:05) 

The impact of Ozempic and insulin resistance (53:15 / 48:00) 

Oxidative stress and the science that currently exists (1:15:45 / 1:05:30) 

Reducing exposure and removing vegetable oils from our diet (1:22:40 / 1:17:20)

Pillars of processed foods (1:41:00 / 1:36:40)

Final thoughts (1:47:00 / 1:42:00) 


Also mentioned in this episode:

Dark Calories: How Vegetable Oils Destroy Our Health and How We Can Get It Back

Simon Hill’s Instagram post


For more on Dr. Shanahan, follow her on Instagram, Facebook, Twitter, or her website. 

Upgrade your digestion with enzymes! Go to bioptimizers.com/dhru now and enter promo code DHRU10 to get 10% off any order and free gifts for a limited time.

Optimize your energy and mental clarity with the purest form of creatine made by and used by the best. Go to livemomentous.com and enter promo code DHRU to get 20% off any order. 

Lumebox is offering my community $260 off their FDA-approved portable Red Light device!  That's over 40% off! Go to thelumebox.com/dhru and get your Red Light device.
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This episode is brought to you by BON CHARGE, Plunge, and Lifeforce. 

When tackling weight loss, most people turn to the tried-and-true methods of cutting calories and increasing exercise. But what if these tactics don't deliver results? How do we safeguard against losing muscle instead of fat? It's time for a paradigm shift: prioritize body recomposition over simply shedding pounds. After all, it's not just about weight loss—it's about crafting a healthier, more resilient body as we age. 

Today on The Dhru Purohit Show, Dhru sits down with JJ Virgin to discuss her top weight loss, muscle building, and vibrant aging strategies. She emphasizes the importance of resistance training for sustained weight loss and tracking individual goals for long-term motivation. Additionally, she shares the secrets she’s learned in her 20-plus years as a celebrity nutritionist, including the most common mistakes women make when trying to lose belly fat, the importance of adding in versus removing, and how to age powerfully.

JJ Virgin is a renowned health and fitness expert, bestselling author, and prominent media personality. With over three decades of experience in the field, she has become a trusted authority in nutrition, weight loss, and wellness. She is the author of four New York Times bestsellers: The Virgin Diet, The Virgin Diet Cookbook, JJ Virgin's Sugar Impact Diet, and JJ Virgin's Sugar Impact Diet Cookbook. Virgin actively contributes to the health and wellness community through speaking engagements, online programs, and her podcast, Well Beyond 40. Her expertise extends beyond nutrition and weight loss as she advocates for a holistic approach to health that encompasses mindset, exercise, and emotional well-being. 

In this episode, Dhru and JJ dive into (audio version / Apple Subscriber version):

Sustained weight loss and belly fat (00:00:30 / 00:00:30)

Resistance training as a critical piece of sustained weight loss (10:45 / 7:25)

Tracking movement and progress (14:00 / 10:30)

Optimal hydration for weight loss (22:10 / 19:54)

The benefits of removing alcohol (28:30 / 25:30) 

Testing body composition (33:00 / 27:52)

Food tracking to get an accurate assessment (39:50 / 34:50)

Aging powerfully (50:45 / 45:45)

Flabby skin and aging (1:01:07 / 56:07)

Japan’s strategy for weight loss as a nation (1:10:30 / 1:05:30)

Childhood obesity (1:19:15 / 1:14:14)

Tracking your protein intake (1:27:10 / 1:22:10)

JJ’s daily routine and protein consumption (1:33:15 / 1:28:15)

Final thoughts (1:37:30 / 1:32:36)


Also mentioned in this episode:

Well Beyond 40 Podcast

Renpho Tape measurer 

Try This: Morning Hydration Challenge

LMNT Electrolytes 

Eat Real 

Cronometer App


For more on JJ Virgin, follow her on Instagram, Facebook, Twitter, YouTube, or through her website. 

Right now, BON CHARGE is offering my community 15% off; just go to boncharge.com/DHRU and use coupon code DHRU to save 15%.

Right now, Plunge is offering my community $150 off cold plunges and their core products. Just go to plunge.com/dhru or enter code DHRU to revolutionize your wellness journey today. 

Right now, you can save $250 on your first diagnostic and get personalized suggestions. Optimize your longevity and track your progress; go to mylifeforce.com/dhru! 
Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Cozy Earth, Fatty15, and Birch Living.

Cardiovascular disease still ranks as the leading cause of death for both men and women. Surprisingly, half of those affected show no symptoms before an event. Low levels of nitric oxide—a molecule that promotes vasodilation and smooth blood flow—could be primarily responsible. By recognizing the signs of deficiency, we can raise our levels and lower our risk.

Today on The Dhru Purohit Show, Dhru sits down for round two with Dr. Nathan Bryan to discuss why nitric oxide is the holy grail of molecules for long-term health. Dr. Bryan shares the four hallmarks of disease, the consequences of antacid overuse, and the correlation between lower nitric oxide and the risk of Alzheimer’s disease. Dr. Bryan also explains which lifestyle factors can hinder and boost nitric oxide production, how to test your levels, and symptoms that signal a deficiency.

Dr. Nathan Bryan is a renowned biomedical researcher known for his groundbreaking work on nitric oxide (NO) biology. Dr. Bryan's research has significantly advanced our understanding of NO's critical roles in cardiovascular health, immune function, and neurobiology. Beyond academia, he advocates for public health, translating his research into practical solutions for improving human health.
 
In this episode, Dhru and Dr. Bryan dive into (audio version / Apple Subscriber version):

Nitric oxide as the holy grail molecule (00:00:02 / 00:00:02)

Four hallmarks of disease (1:01 / 1:01) 

Antacid medications: lack of research and the consequences of extended use (4:41 / 4:41)

Lower nitric oxide and the risk of Alzheimer’s (14:00 / 10:45)

Lifestyle habits that contribute to Alzheimer’s and biomarkers to check (17:15 /13:01)

What is nitric oxide and its core role in our bodies (27:00  / 23:39)

Lifestyle factors that hinder nitric oxide production (33:00 / 28:22) 

Nitric oxide and high blood pressure (46:00 / 41:04) 

Filtering water in your home and oral dysbiosis (51:00 / 46:30)

Navigating antacid medication usage and tapering off (1:11:00 / 1:06:50)

Testing nitric oxide level production (1:15:00 / 1:10:06)

The role of stress on our nitric oxide levels (1:29:00 / 1:24:53)

Foods that support production and supplementation (1:32:00 / 1:27:10)

Final thoughts: (1:44:00 / 1:39:40) 


Also mentioned in this episode:


N1O1.com (get 10% off any of Dr. Bryan’s nitric oxide products with the code DHRU) 

Bryan Therapeutics

EWG

Fygg Toothpaste 


For more on Dr. Bryan, follow him on Instagram, Twitter, YouTube, and through his website, 
 
Right now, get 30% off your Cozy Earth sheets. Just head over to cozyearth.com/dhru and use code DHRUP.

Fatty15 is offering an additional 15% off its 90-day subscription Starter Kit. Go to fatty15.com/dhru and use code DHRU to replenish your C15 levels for long-term health. 

To get 25% off your Birch Living mattress plus two free eco-rest pillows, head over to birchliving.com/dhru today.
Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Lumebox and AquaTru.

Numerous experts have explored the myriad factors associated with chronic disease. However, our guest today sheds light on an often overlooked factor: junk light. Our modern lifestyles frequently experience diminished exposure to natural sunlight and constant exposure to blue light emitted by phones, devices, and indoor workspaces. Dr. Alexis Cowan emphasizes the importance of minimizing our exposure to junk light and maximizing sunlight for our health.

Today on The Dhru Purohit Show, Dhru sits down with Dr. Alexis Cowan to discuss the impact of junk light on our well-being and longevity. Dr. Cowan explains how exposure to junk light can alter our circadian rhythm and hormone levels, disrupting our sleep patterns and eating behaviors. Additionally, she underscores the significance of sunlight exposure for weight management, mood regulation, and daily motivation. Dr. Cowan offers practical tips to minimize blue light exposure and incorporate red light therapy for those unable to attain optimal sun exposure in their daily routines.

Dr. Alexis Cowan is a Princeton-trained PhD in molecular biology who operates at the interface of physiology and metabolism. She specializes in circadian biology, microbiome-host interactions, and the metabolic effects of nutritional and exercise modalities. Dr. Alexis teaches coursework on topics in health, translational science, and scientific literacy. She also sees highly motivated clients in a one-on-one capacity. 

In this episode, Dhru and Dr. Cowan dive into (audio version / Apple Subscriber version):

Junk light as a contributor to chronic disease (00:00:05 / 00:00:05)

The implications of having too much junk light (8:00 / 6:37)

What does the absence of sunlight and too much junk light cause (12:00 /10:05)

How much sun should you get a day and build up your tolerance (16:00 / 14:20)

Skin cancer risks (21:50 / 20:05)

What damages skin and causes aging (25:00 / 23:19)

The correlation between melanoma and skin cancer (31:30 / 28:50)

Metabolism, weight loss, and sunlight exposure (38:40 / 33:30)

Simple hacks to reduce your blue light exposure (39:20 / 36:05)

Red light therapy (44:20 / 41:03)

Dr. Cowan’s journey (47:00 / 43:54)

Akkermansia for gut health and immunity (51:40 / 48:30)

Sunlight and motivation and goals (1:00:00 / 53:52)

Final thoughts (1:01:30 / 58:00)


Also mentioned in this episode:

Dr. Cowan’s Podcast, Undoctrinate Yourself 

Study on LASIK surgery 

Melanoma Exposure Study

Study about high occupational sun exposure seemed to be inversely associated with melanoma

Sun exposure is associated with increased survival from melanoma

Study about low UV exposure and Vitamin D levels related to increased mortality due to skin cancer

Study about the positive association between melanoma risk and intermittent sun exposure in contrast to reduced risk with high levels of occupational exposure 


For more on Dr. Alexis Cowan, follow her on Instagram and via her site.

Lumebox is offering my community $260 off their FDA-approved portable Red Light device! That's over 40% off! Go to thelumebox.com/dhru and get your Red Light device.

AquaTru is a countertop reverse osmosis purifier with a four-stage filtration system that removes 15x more contaminants than the bestselling water filters out there. Go to dhrupurohit.com/filter/ and get $100 off when you try AquaTru for yourself.
Learn more about your ad choices. Visit megaphone.fm/adchoices