11 afleveringen

The conference will represent a unique forum to discuss the most recent and unpublished findings on the basic biology of replication fork perturbation and repair as well as on our current understanding of how replicative stress drives cancer and aging. Session topics will include: Basic mechanisms at the replication fork, Replication-repair interface, Replication fork remodeling, Structural and single molecule analysis of replication/repair, Replication-transcription interface, Replication-recombination interface Chromatin, replication and genome maintenance, Difficult-to-replicate loci and telomers, Replication stress in cancer onset and therapy.

At the Intersection of DNA Replication and Genome Maintenance: from Mechanisms to Therapy ICGEB Podcasts

    • Wetenschap

The conference will represent a unique forum to discuss the most recent and unpublished findings on the basic biology of replication fork perturbation and repair as well as on our current understanding of how replicative stress drives cancer and aging. Session topics will include: Basic mechanisms at the replication fork, Replication-repair interface, Replication fork remodeling, Structural and single molecule analysis of replication/repair, Replication-transcription interface, Replication-recombination interface Chromatin, replication and genome maintenance, Difficult-to-replicate loci and telomers, Replication stress in cancer onset and therapy.

    • video
    O. Fernandez-Capetillo - Mechanisms of resistance to anticancer therapies

    O. Fernandez-Capetillo - Mechanisms of resistance to anticancer therapies

    Oscar Fernandez-Capetillo, Spanish National Cancer Res. Center, Madrid , speaks on "Mechanisms of resistance to anticancer therapies. "This movie has been recorded by ICGEB Trieste at "At the Intersection of DNA Replication and Genome Maintenance: 2016 - from Mechanism to Therapy" conference.

    • 22 min.
    • video
    S. Mirkin - Mechanisms of genome instability mediated by interstitial telomeric sequences

    S. Mirkin - Mechanisms of genome instability mediated by interstitial telomeric sequences

    Sergei Mirkin, Tufts University, Medford, speaks on "Mechanisms of genome instability mediated by interstitial telomeric sequences". This movie has been recorded by ICGEB Trieste at "At the Intersection of DNA Replication and Genome Maintenance: 2016 - from Mechanism to Therapy" conference.

    • 21 min.
    • video
    I. Whitehouse - Coupling of gene enhancers and replication origins

    I. Whitehouse - Coupling of gene enhancers and replication origins

    Iestyn Whitehouse, Memorial Sloan-Kettering CC, New York, speaks on "Coupling of gene enhancers and replication origins". This movie has been recorded by ICGEB Trieste at "At the Intersection of DNA Replication and Genome Maintenance: 2016 - from Mechanism to Therapy" conference.

    • 22 min.
    • video
    A. Constantinou - A FANCM protein interaction screen reveals a pyrimidine catabolism enzyme required to prevent cell-intrinsic DNA replication stress

    A. Constantinou - A FANCM protein interaction screen reveals a pyrimidine catabolism enzyme required to prevent cell-intrinsic DNA replication stress

    Angelos Constantinou, Institute of Human Genetics, Montpellier, speaks on "A FANCM protein interaction screen reveals a pyrimidine catabolism enzyme required to prevent cell-intrinsic DNA replication stress ". This movie has been recorded by ICGEB Trieste at "At the Intersection of DNA Replication and Genome Maintenance: 2016 - from Mechanism to Therapy" conference.

    • 20 min.
    • video
    J. Berger - Structural mechanisms for initiating DNA replication

    J. Berger - Structural mechanisms for initiating DNA replication

    James Berger, Johns Hopkins, Baltimore, speaks on "Structural mechanisms for initiating DNA replication". This movie has been recorded by ICGEB Trieste at "At the Intersection of DNA Replication and Genome Maintenance: 2016 - from Mechanism to Therapy" conference.

    • 23 min.
    • video
    W. Yang - Molecular gymnastics during DNA translesion synthesis

    W. Yang - Molecular gymnastics during DNA translesion synthesis

    Wei Yang, NIDDK, NIH, Bethesda, speaks on "Molecular gymnastics during DNA translesion synthesis". This movie has been recorded by ICGEB Trieste at "At the Intersection of DNA Replication and Genome Maintenance: 2016 - from Mechanism to Therapy" conference.

    • 24 min.

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