Treating Older AML Patients and Managing Unique Toxicities Medscape InDiscussion: Acute Myeloid Leukemia

Drs Gail Roboz and Courtney DiNardo discuss methods of treating older patients with acute myeloid leukemia and managing unique toxicities.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/964537). The topics and discussions are planned, produced, and reviewed independently of advertiser. This podcast is intended only for US healthcare professionals.
Resources
Acute Myeloid Leukemia https://emedicine.medscape.com/article/197802-overview
Cytarabine https://reference.medscape.com/drug/cytosar-u-depocyt-cytarabine-342089
Mylotarg (gemtuzumab ozogamicin) https://reference.medscape.com/drug/mylotarg-gemtuzumab-1000186
A Phase 3 Trial of Azacitidine Versus a Semi-Intensive Fludarabine and Cytarabine Schedule in Older Patients With Untreated Acute Myeloid Leukemia https://pubmed.ncbi.nlm.nih.gov/33626197/
Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia https://www.nejm.org/doi/full/10.1056/NEJMoa2012971
Ferrara Criteria https://decisionpoint.medscape.com/oncology/viewarticle/928810
Hydrea https://reference.medscape.com/drug/droxia-siklos-hydroxyurea-342100
Mucositis https://emedicine.medscape.com/article/1079570-overview
Azacytidine https://reference.medscape.com/drug/onureg-vidaza-azacitidine-342263
Decitabine https://reference.medscape.com/drug/dacogen-decitabine-342091
Venetoclax https://reference.medscape.com/drug/venclexta-venetoclax-1000078
Hydroxycarbamide in Combination With Azacitidine or Decitabine Is Antagonistic on DNA Methylation Inhibition https://pubmed.ncbi.nlm.nih.gov/17686055/