24 min

Challenges and Opportunities: Treatment and Prevention of Moderate to Severe Childhood Asthma Medscape InDiscussion: Moderate to Severe Asthma

    • Science

Drs Wechsler, Bacharier, and Phipatanakul discuss moderate to severe childhood asthma.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/969691). The topics and discussions are planned, produced, and reviewed independently of advertiser. This podcast is intended only for US healthcare professionals.
Resources:
Precision Interventions for Severe and/or Exacerbation-Prone Asthma (PrecISE) Network https://preciseasthma.org/preciseweb/
Inhaled Corticosteroid Therapy in Children: An Assessment of the Potential for Side Effects https://www.ncbi.nlm.nih.gov/pmc/articles/PMC475319/pdf/thorax00304-0005.pdf
Inhaled Corticosteroids in Children: Effects on Bone Mineral Density and Growth https://linkinghub.elsevier.com/retrieve/pii/S2213-2600(14)70024-4
Aerochamber https://aerochamber.com/
Pulmonary Function Testing https://emedicine.medscape.com/article/303239-overview
Using Impulse Oscillometry in Clinical Practice https://www.medscape.com/viewarticle/862265
Global Initiative for Asthma Guidelines https://ginasthma.org/
National Asthma Education Prevention Program Guidelines https://www.nhlbi.nih.gov/health-topics/asthma-management-guidelines-2020-updates
Omalizumab Prescribing Information https://www.gene.com/download/pdf/xolair_prescribing.pdf
Mepolizumab Prescribing Information https://gskpro.com/content/dam/global/hcpportal/en_US/Prescribing_Information/Nucala/pdf/NUCALA-PI-PIL-IFU-COMBINED.PDF
Benralizumab Prescribing Information https://den8dhaj6zs0e.cloudfront.net/50fd68b9-106b-4550-b5d0-12b045f8b184/3647bed4-ce91-4fe7-9bc5-32dbee73f80a/3647bed4-ce91-4fe7-9bc5-32dbee73f80a_viewable_rendition__v.pdf
Dupilumab in Children With Uncontrolled Moderate-to-Severe Asthma https://www.nejm.org/doi/10.1056/NEJMoa2106567
Dupilumab Prescribing Information https://www.regeneron.com/downloads/dupixent_fpi.pdf
Tezepelumab Prescribing Information https://den8dhaj6zs0e.cloudfront.net/50fd68b9-106b-4550-b5d0-12b045f8b184/e306dc06-d580-4457-b15f-9f28545ad63a/e306dc06-d580-4457-b15f-9f28545ad63a_viewable_rendition__v.pdf
Preventing Asthma in High Risk Kids (PARK) With Omalizumab: Design, Rationale, Methods, Lessons Learned and Adaptation https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887056/

Drs Wechsler, Bacharier, and Phipatanakul discuss moderate to severe childhood asthma.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/969691). The topics and discussions are planned, produced, and reviewed independently of advertiser. This podcast is intended only for US healthcare professionals.
Resources:
Precision Interventions for Severe and/or Exacerbation-Prone Asthma (PrecISE) Network https://preciseasthma.org/preciseweb/
Inhaled Corticosteroid Therapy in Children: An Assessment of the Potential for Side Effects https://www.ncbi.nlm.nih.gov/pmc/articles/PMC475319/pdf/thorax00304-0005.pdf
Inhaled Corticosteroids in Children: Effects on Bone Mineral Density and Growth https://linkinghub.elsevier.com/retrieve/pii/S2213-2600(14)70024-4
Aerochamber https://aerochamber.com/
Pulmonary Function Testing https://emedicine.medscape.com/article/303239-overview
Using Impulse Oscillometry in Clinical Practice https://www.medscape.com/viewarticle/862265
Global Initiative for Asthma Guidelines https://ginasthma.org/
National Asthma Education Prevention Program Guidelines https://www.nhlbi.nih.gov/health-topics/asthma-management-guidelines-2020-updates
Omalizumab Prescribing Information https://www.gene.com/download/pdf/xolair_prescribing.pdf
Mepolizumab Prescribing Information https://gskpro.com/content/dam/global/hcpportal/en_US/Prescribing_Information/Nucala/pdf/NUCALA-PI-PIL-IFU-COMBINED.PDF
Benralizumab Prescribing Information https://den8dhaj6zs0e.cloudfront.net/50fd68b9-106b-4550-b5d0-12b045f8b184/3647bed4-ce91-4fe7-9bc5-32dbee73f80a/3647bed4-ce91-4fe7-9bc5-32dbee73f80a_viewable_rendition__v.pdf
Dupilumab in Children With Uncontrolled Moderate-to-Severe Asthma https://www.nejm.org/doi/10.1056/NEJMoa2106567
Dupilumab Prescribing Information https://www.regeneron.com/downloads/dupixent_fpi.pdf
Tezepelumab Prescribing Information https://den8dhaj6zs0e.cloudfront.net/50fd68b9-106b-4550-b5d0-12b045f8b184/e306dc06-d580-4457-b15f-9f28545ad63a/e306dc06-d580-4457-b15f-9f28545ad63a_viewable_rendition__v.pdf
Preventing Asthma in High Risk Kids (PARK) With Omalizumab: Design, Rationale, Methods, Lessons Learned and Adaptation https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7887056/

24 min

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