Official Podcast of the Breast Cancer Research Foundation
Understanding Global Breast Cancer Disparities with Dr. Temidayo Fadelu
While academic and medical research has led to incredible breakthroughs in breast cancer care—including new treatments and screening methods—these advances have not reached every patient in every corner of the globe. With breast cancer now the most commonly diagnosed cancer in the world, it’s critical that lifesaving advances are deployed more equitably and universally—especially to women and men in lower-income and -resource countries. Dr. Fadelu discussed his work that lies at the intersection of breast cancer and global health services research
Each year, BCRF underwrites several grants to breast cancer researchers in partnership with Conquer Cancer, the ASCO Foundation. Dr. Temidayo Fadelu recently received the Career Development Award for Diversity, Inclusion and Breast Cancer Disparities. His BCRF-supported project aims to improve adherence to endocrine therapies among patients in Rwanda and Haiti.
Unraveling the Mysteries of Inherited Gene Mutations with Dr. Ephrat Levy-Lahad
How can genetic testing data encourage prevention and agency without amplifying personal fear? What can research reveal about genetic markers of risk and predisposition? Or, put differently, how can understanding one’s inherited risk improve approaches to precision prevention?
Dr. Ephrat Levy-Lahad is on the forefront of this research, focusing on breast cancer–associated genetic mutations among various populations, including Arab and Ashkenazi Jewish women. She is a professor of internal medicine and medical genetics at Hebrew University and director of the Medical Genetics Institute at Shaare Zedek Medical Center in Jerusalem.
Perfecting and Personalizing Risk Assessment with Dr. Katherine Nathanson
While breast cancer is not typically caused by inherited factors, as many as 10-15 percent of people diagnosed with breast cancer carry a known genetic mutation. The most well-known mutations are in the BRCA1 and BRCA2 genes. But these only account for 5-10 percent of inherited breast cancers, so what about the many other gene mutations that increase a person’s risk of breast cancer? Also, what does this mean not only for genetic testing—but also how we should consider results? More significantly, what effect might this have on the personalization of risk?
We talk with BCRF investigator and cancer geneticist Dr. Katherine Nathanson to answer these questions.
New Approaches to Reducing Repeat Breast Cancer Surgeries with Dr. Mehra Golshan
There are many challenges in managing breast cancer. Top among them is the fact that initial breast conserving surgeries often miss vestiges of a patient’s tumor. In fact, up to 40 percent of women require another procedure following lumpectomy. Not only can additional surgery, of course, increase a patient’s anxiety and be physically taxing, but it can cause delays in critical subsequent treatments like chemotherapy and radiation.
So, why is that rate so high? Why is properly identifying the tumor so difficult? Most importantly: What can be done to reduce repeat surgeries? Dr. Mehra Golshan is working to uncover answers to these questions.
A BCRF investigator since 2014, Dr. Golshan is the deputy chief medical officer for surgical services and director of the Breast Cancer Program for the Yale Cancer Center, Smilow Cancer Hospital, and Smilow Cancer Hospital Care Centers.
Improving the Quality of Life for Breast Cancer Patients and Survivors with Professor Dame Lesley Fallowfield
How do you measure quality of life? As researchers across fields discover new drug therapies or disease prevention—in breast cancer as well as other fields—science finds innumerable ways to measure physical results. But what about the social, behavioral, and psychological aspects of cancer care? And how should medical providers discuss such realties with patients?
This is just one area of extraordinary impact that Professor Dame Lesley Fallowfield has made in medicine. Dame Lesley is professor of psycho-oncology at Brighton & Sussex Medical School at the University of Sussex where she is director of the Sussex Health Outcomes Research & Education in Cancer group.
She has been a BCRF Investigator since 2016—the same year she was made a Dame Commander of the Order of the British Empire by Queen Elizabeth II for services to psycho-oncology.
Understanding Radiation Resistance and Barriers to Quality Care with Dr. Lori Pierce
For so many breast cancer patients, radiation therapy can bring extraordinary benefits—top among them improved survival rates and reduced recurrence. But there are also challenges and questions: Why do some people experience a recurrence after treatment? How can we reduce side effects? How can we ensure the right patients receive radiation therapy—and that the treatment works as well as possible?
These are among the many medical mysteries to which Dr. Lori Pierce, BCRF investigator since 2003, has dedicated her career to answering.
These podcasts are excellent!
Legitimate and timely
Legitimate. Timely. What I was looking for.
I love to hear about breast cancer info but the talk is just too scientific that a lot of things I don’t understand what they’re saying or maybe it’s just me