56 episodes

Podcast interviews with authors of articles published in The Journal of Applied Laboratory Medicine.

JALM Talk Podcast American Association for Clinical Chemistry

    • Medicine

Podcast interviews with authors of articles published in The Journal of Applied Laboratory Medicine.

    Bad Tests Die Slowly: The Myelin Basic Protein Example

    Bad Tests Die Slowly: The Myelin Basic Protein Example

    • 6 min
    Reproducible Research and Reports with R

    Reproducible Research and Reports with R

    • 14 min
    Practical Approach to Eliminate Bilirubin Interference in Icteric Samples for Creatinine Measurement

    Practical Approach to Eliminate Bilirubin Interference in Icteric Samples for Creatinine Measurement

    Clinical chemistry assays are widely impacted by inherent interferences in patient blood samples such as hemolysis, icterus, and lipemia.  These interferences can cause inaccurate laboratory results and may even prevent the laboratory from releasing test results to ordering health care providers.  In particular, the interference of bilirubin in various creatinine assays is common.  Inaccurately reported creatinine, or the inability to report creatinine, can have adverse implications in the management of patients.  Accurate creatinine results are important for assessing kidney function in many clinical contexts such as imaging procedures and the dosing of therapeutic drugs.  Therefore, mechanisms to overcome bilirubin interference and creatinine assays would be beneficial to patient care. The November 2019 issue of The Journal of Applied Laboratory Medicine includes a Laboratory Reflections article entitled, “A Practical Approach to Eliminate Bilirubin Interference in Icteric Samples for Creatinine Measurement.”

    • 7 min
    Laboratory Test Utilization and Repeat Testing for Inpatients of Age 80 and Over in Australia

    Laboratory Test Utilization and Repeat Testing for Inpatients of Age 80 and Over in Australia

    An original research article published in the September 2019 issue of the Journal of Applied Laboratory Medicine describes a study which investigated whether laboratory tests were being properly utilized for hospitalized patients aged 80 years and older.

    • 8 min
    A Multicenter Assessment of the Sensitivity and Specificity for a Single High-Sensitivity Cardiac Troponin Test at Emergency Department Presentation for Hospital Admission

    A Multicenter Assessment of the Sensitivity and Specificity for a Single High-Sensitivity Cardiac Troponin Test at Emergency Department Presentation for Hospital Admission

    An original research article published in the September 2019 issue of the Journal of Applied Laboratory Medicine describes the validation of a clinical chemistry score which incorporates high sensitivity troponin with other laboratory results of glucose and estimated glomerular filtration rate as an alternative assessment strategy for emergency room patients with possible myocardial infarction.

    • 12 min
    Development of Reference Materials for Noninvasive Prenatal Aneuploidy Testing by Massively Parallel Sequencing: A Proof-of-Concept Study

    Development of Reference Materials for Noninvasive Prenatal Aneuploidy Testing by Massively Parallel Sequencing: A Proof-of-Concept Study

    An original research article published in the July 2019 issue of the Journal of Applied Laboratory Medicine, describes a proof-of-concept study which tested the possibility of using artificial plasma matrix spiked with fragmented genomic DNA from immortalized cell lines to produce reference material for noninvasive prenatal testing assays. 

    • 8 min

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