31 min

7.2- Jean-Paul Pirnay: 100 cases of Phage Therapy in Belgium (Part 2/2‪)‬ PhageCast

    • Life Sciences

You can hear the first of two parts of our interview with Jean-Paul Pirnay:Senior Scientist and currently Head of the Laboratory for Molecular and Cellular Technology (LabMCT) in Queen Astrid Military Hospital, Jean-Paul Pirnay is very well known in our field for his work in Belgium regarding the use of phages against bacterial infections.We covered in this conversation their first 100 documented cases of phage therapy in Belgium.

In the first part you heard how phage therapy is done in Belgium, how it started and his view on phage therapy today, and how it will be done in the future.You also got a first glance into the data of their 100 first cases and their treatment efficacy rates, adverse reactions, the main infections they are treating, the limitations and bottlenecks of the study and the process, etc. (link here in the end of the description)------------------------------------------The second part of the conversation covers all other details like how to deal with phage resistance, how phages are selected for use in patients, the use of phages in combination with antibiotics, how they do their phage adaptations… and you will get to hear some of Jean-Paul´s advice to PhD students and early career researchers!-------------------------------------------Stay till the end and we hope you enjoy the episode as much as we did!https://www.medrxiv.org/content/10.1101/2023.08.28.23294728v1Retrospective, observational analysis of the first one hundred consecutive cases of personalized bacteriophage therapy of difficult-to-treat infections facilitated by a Belgian consortium

You can hear the first of two parts of our interview with Jean-Paul Pirnay:Senior Scientist and currently Head of the Laboratory for Molecular and Cellular Technology (LabMCT) in Queen Astrid Military Hospital, Jean-Paul Pirnay is very well known in our field for his work in Belgium regarding the use of phages against bacterial infections.We covered in this conversation their first 100 documented cases of phage therapy in Belgium.

In the first part you heard how phage therapy is done in Belgium, how it started and his view on phage therapy today, and how it will be done in the future.You also got a first glance into the data of their 100 first cases and their treatment efficacy rates, adverse reactions, the main infections they are treating, the limitations and bottlenecks of the study and the process, etc. (link here in the end of the description)------------------------------------------The second part of the conversation covers all other details like how to deal with phage resistance, how phages are selected for use in patients, the use of phages in combination with antibiotics, how they do their phage adaptations… and you will get to hear some of Jean-Paul´s advice to PhD students and early career researchers!-------------------------------------------Stay till the end and we hope you enjoy the episode as much as we did!https://www.medrxiv.org/content/10.1101/2023.08.28.23294728v1Retrospective, observational analysis of the first one hundred consecutive cases of personalized bacteriophage therapy of difficult-to-treat infections facilitated by a Belgian consortium

31 min