Investigating Breast Cancer BCRF

In this latest episode, Dr. Jose Pablo Leone discusses the need for a better understanding of male breast cancer to improve treatment options.
Dr. Leone is a medical oncologist and clinical investigator in the Breast Oncology Center at Dana-Farber Cancer Institute, where he also serves as the director of the Program for Breast Cancer in Men. Dr. Leone’s research focuses on brain metastases, male breast cancer, and research involving large databases, and he has been a BCRF investigator since 2023.

Dr. Shelley Hwang––BCRF investigator since 2016–– is an experienced clinical trialist with an interest in both the biology and treatment of early-stage breast cancer. In this episode, she discusses the urgent need to better understand Ductal Carcinoma in Situ (DCIS) and the work she and her team are doing to uncover better treatment options for patients with DCIS.

In the latest episode of Investigating Breast Cancer, Dr. Adrian Lee discusses collaboration, strategies to improve treatment for ILC, and more. A BCRF investigator since 2013, he is the Pittsburgh Foundation chair and director of the Institute for Precision Medicine at the University of Pittsburgh and UPMC

In the latest episode, Dr. Rachel Jimenez discusses a new strategy of delivering radiation called proton beam radiation that could reduce treatment time and minimize its damaging effects on the heart. Unlike traditional radiation, proton therapy radiation can target cancer cells specifically, sparing other healthy tissues from potential damage.
Dr. Jimenez is an assistant professor of radiation oncology at Harvard Medical School and the chair for quality and safety in the department of radiation oncology at Massachusetts General Hospital.

Dr. Laura Esserman talks about her current research that examines how fiber shapes the gut microbiome, potentially improving the response to immune agents in women newly diagnosed with breast cancer.
Her prior research looked at how immune cells in tumors influence tumor response to immune drugs, and she believes the gut microbiome plays a key role in this complex system.
A BCRF investigator since 1998, Dr. Esserman is an internationally recognized breast surgeon, breast oncology specialist, and personalized medicine visionary.

In October, BCRF holds its annual New York Symposium and Awards Luncheon. The event recognizes BCRF-supported investigators for their devotion to ending breast cancer and announces the Foundation’s research investment for the coming year.
In this special episode of Investigating Breast Cancer, you’ll hear this year’s  extraordinary symposium, co-moderated by BCRF Founding Scientific Director Dr. Larry Norton and BCRF Scientific Director Dr. Judy Garber, that included Drs. Seema Khan, Constance D. Lehman, and Olufunmilayo I. Olopade.