Dr Ann Silver - Audio UCL
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- Health & Fitness
Dr Ann Silver studied physiology at Edinburgh University where she completed a PhD (1960) as an external student whilst carrying out research at the Agricultural Research Council Institute of Animal Physiology at Babraham, Cambridgeshire. Her research involved electrophysiological studies of nerve fibres exposed to organophosphorous compounds and also the transport of choline acetyltransferase down nerves.
Dr Silver’s book, Biology of Cholinesterases (1974), was an important source of information, ideas and inspiration for a generation of cholinesterase researchers. She later laid the foundations for the ‘cholinergic hypothesis’ of Alzheimer’s disease, which led to the development of acetylcholinesterase inhibitors to treat it. She has been ethical editor on the Journal of Physiology and was involved in drafting the Animals (Scientific Procedures) Act 1986, which regulates the ways in which animal experimentation is conducted in the UK.
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19. Ethical matters - Animals (Scientific Procedures) Act 1986
UCL History of Medicine
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18. Ethical matters ethical editor on the Journal of Physiology
UCL History of Medicine
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17. Ethical matters out of the lab to become Information Officer
UCL History of Medicine
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16. The Biology of Cholinesterases, North Holland American Elsevier, 1974 comprehensive review of function and distribution of cholinesterases in vertebrates and invertebrates
UCL History of Medicine
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15. Anticholinesterases DFP and safety precautions
UCL History of Medicine
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14. Anticholinesterases organophosphorous toxicity and an incident in Morocco, 1959
UCL History of Medicine