16 min

Episodio 03 - Vacunas RNAm Hablemos de COVID-19

    • Medicine

Hablemos un poco sobre las vacunas de RNAm respecto a lo que tenemos hoy en la evidencia, sobre su seguridad, poblaciones a vacunar y seguridad. 



1. Polack, F., et al. 2020. Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine. engl j med 383;27.

2. Thompson MG. Et al. Interim Estimates of Vaccine Effectiveness of BNT162b2 and mRNA-1273 COVID-19 Vaccines in Preventing SARS-CoV-2 Infection Among Health Care Personnel, First Responders, and Other Essential and Frontline Workers - Eight U.S. Locations, December 2020-March 2021. MMWR Morb Mortal Wkly Rep. 2021 Apr 2;70(13):495-500. doi: 10.15585/mmwr.mm7013e3. PMID: 33793460.

3. Britton, A.. Et al (2021). Effectiveness of the Pfizer-BioNTech COVID-19 Vaccine Among Residents of Two Skilled Nursing Facilities Experiencing COVID-19 Outbreaks - Connecticut, December 2020-February 2021. MMWR. Morbidity and mortality weekly report, 70(11), 396–401. https://doi.org/10.15585/mmwr.mm7011e3

4. Shimabukuri, T.T. et al. 2021. Preliminary findings of mRNA Covid-19 Vaccine Safety in Pregnant persons. NEJM, April,DOI: 10.1056/NEJMoa2104983.

5. Rinott, E., Youngster, I. y Lewis, YE (2021). Reduction in COVID-19 Patients Requiring Mechanical Ventilation Following Implementation of a National COVID-19 Vaccination Program — Israel, December 2020–February 2021. MMWR. Informe semanal de morbilidad y mortalidad , 70 (9), 326-328. https://doi.org/10.15585/mmwr.mm7009e3

6. Haas, E, J. et al. 2021- Impact and effectiveness of mRNA BNT162b2 vaccine against SARS-CoV-2 infections and COVID-19 cases, hospitalisations, and deaths following a nationwide vaccination campaign in Israel: an observational study using national surveillance data. The Lancet, ISSN 0140-6736, https://doi.org/10.1016/S0140-6736(21)00947-8.

7. Monin,. L. et al. 2021. Safety and immunogenicity of one versus two doses of the COVID-19 vaccine BNT162b2 for patients with cancer: interim analysis of a prospective observational study. April DOI:https://doi.org/10.1016/S1470-2045(21)00213-8.

8. Baden,. L R. et al. 2020. Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine. N Engl J Med 2021; 384: 403-416. DOI: 10.1056 / NEJMoa2035389.

9. Remmel,. A. 2021. COVID vaccines and safety: what the research says. Nature, Disponible en: https://www.nature.com/articles/d41586-021-00290-x. Accesado el 04 de mayo del 2021.     

10. Tenforde MW, Olson SM, Self WH, et al. Effectiveness of Pfizer-BioNTech and Moderna Vaccines Against COVID-19 Among Hospitalized Adults Aged ≥65 Years — United States, January–March 2021. MMWR Morb Mortal Wkly Rep. ePub: 28 April 2021. DOI: http://dx.doi.org/10.15585/mmwr.mm7018e1external.

11. Baden LR. Et al. 2021. Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine. N Engl J Med. 2021 Feb 4;384(5):403-416. doi: 10.1056/NEJMoa2035389. Epub 2020 Dec 30. PMID: 33378609; PMCID: PMC7787219.

12. Meo SA, Bukhari IA, Akram J, Meo AS, Klonoff DC. COVID-19 vaccines: comparison of biological, pharmacological characteristics and adverse effects of Pfizer/BioNTech and Moderna Vaccines. Eur Rev Med Pharmacol Sci. 2021 Feb;25(3):1663-1669. doi: 10.26355/eurrev_202102_24877. PMID: 33629336.

Link New York Times para Pfizer: https://www.nytimes.com/interactive/2020/health/pfizer-biontech-covid-19-vaccine.html

Link New York times para Moderna: 

https://www.nytimes.com/interactive/2020/health/moderna-covid-19-vaccine.html



Derechos de música: 

"Scandinavianz - Breeze" is under a Creative Commons (CC BY 3.0) license.

https://youtu.be/0GbM2rL0HCY


Music promoted by BreakingCopyright: https://youtu.be/0IkBSGqevFQ

Hablemos un poco sobre las vacunas de RNAm respecto a lo que tenemos hoy en la evidencia, sobre su seguridad, poblaciones a vacunar y seguridad. 



1. Polack, F., et al. 2020. Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine. engl j med 383;27.

2. Thompson MG. Et al. Interim Estimates of Vaccine Effectiveness of BNT162b2 and mRNA-1273 COVID-19 Vaccines in Preventing SARS-CoV-2 Infection Among Health Care Personnel, First Responders, and Other Essential and Frontline Workers - Eight U.S. Locations, December 2020-March 2021. MMWR Morb Mortal Wkly Rep. 2021 Apr 2;70(13):495-500. doi: 10.15585/mmwr.mm7013e3. PMID: 33793460.

3. Britton, A.. Et al (2021). Effectiveness of the Pfizer-BioNTech COVID-19 Vaccine Among Residents of Two Skilled Nursing Facilities Experiencing COVID-19 Outbreaks - Connecticut, December 2020-February 2021. MMWR. Morbidity and mortality weekly report, 70(11), 396–401. https://doi.org/10.15585/mmwr.mm7011e3

4. Shimabukuri, T.T. et al. 2021. Preliminary findings of mRNA Covid-19 Vaccine Safety in Pregnant persons. NEJM, April,DOI: 10.1056/NEJMoa2104983.

5. Rinott, E., Youngster, I. y Lewis, YE (2021). Reduction in COVID-19 Patients Requiring Mechanical Ventilation Following Implementation of a National COVID-19 Vaccination Program — Israel, December 2020–February 2021. MMWR. Informe semanal de morbilidad y mortalidad , 70 (9), 326-328. https://doi.org/10.15585/mmwr.mm7009e3

6. Haas, E, J. et al. 2021- Impact and effectiveness of mRNA BNT162b2 vaccine against SARS-CoV-2 infections and COVID-19 cases, hospitalisations, and deaths following a nationwide vaccination campaign in Israel: an observational study using national surveillance data. The Lancet, ISSN 0140-6736, https://doi.org/10.1016/S0140-6736(21)00947-8.

7. Monin,. L. et al. 2021. Safety and immunogenicity of one versus two doses of the COVID-19 vaccine BNT162b2 for patients with cancer: interim analysis of a prospective observational study. April DOI:https://doi.org/10.1016/S1470-2045(21)00213-8.

8. Baden,. L R. et al. 2020. Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine. N Engl J Med 2021; 384: 403-416. DOI: 10.1056 / NEJMoa2035389.

9. Remmel,. A. 2021. COVID vaccines and safety: what the research says. Nature, Disponible en: https://www.nature.com/articles/d41586-021-00290-x. Accesado el 04 de mayo del 2021.     

10. Tenforde MW, Olson SM, Self WH, et al. Effectiveness of Pfizer-BioNTech and Moderna Vaccines Against COVID-19 Among Hospitalized Adults Aged ≥65 Years — United States, January–March 2021. MMWR Morb Mortal Wkly Rep. ePub: 28 April 2021. DOI: http://dx.doi.org/10.15585/mmwr.mm7018e1external.

11. Baden LR. Et al. 2021. Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine. N Engl J Med. 2021 Feb 4;384(5):403-416. doi: 10.1056/NEJMoa2035389. Epub 2020 Dec 30. PMID: 33378609; PMCID: PMC7787219.

12. Meo SA, Bukhari IA, Akram J, Meo AS, Klonoff DC. COVID-19 vaccines: comparison of biological, pharmacological characteristics and adverse effects of Pfizer/BioNTech and Moderna Vaccines. Eur Rev Med Pharmacol Sci. 2021 Feb;25(3):1663-1669. doi: 10.26355/eurrev_202102_24877. PMID: 33629336.

Link New York Times para Pfizer: https://www.nytimes.com/interactive/2020/health/pfizer-biontech-covid-19-vaccine.html

Link New York times para Moderna: 

https://www.nytimes.com/interactive/2020/health/moderna-covid-19-vaccine.html



Derechos de música: 

"Scandinavianz - Breeze" is under a Creative Commons (CC BY 3.0) license.

https://youtu.be/0GbM2rL0HCY


Music promoted by BreakingCopyright: https://youtu.be/0IkBSGqevFQ

16 min