Dhru Purohit Show Dhru Purohit

This episode is brought to you by Cozy Earth, Maui Nui, and Lumebox.

We’ve heard about Dr. Thomas Seyfried’s groundbreaking research and approach to cancer as a disease of metabolic dysfunction. Today’s guest was inspired by Dr. Seyfried’s metabolic approach and conducted his own research on brain cancer cells using ketone-based metabolic therapy and hyperbaric oxygen. His findings were mind-blowing!
Today on The Dhru Purohit Podcast, Dhru sits down with Dr. Dominic D’Agostino to discuss his extensive research on brain cancer cells placed in ketosis and under the pressure of hyperbaric oxygen. Dr. D’Agostino shares why his findings provide further insight into the idea that cancer cell growth can be metabolically managed. He also discusses how exercise and a low-carbohydrate diet can be used as metabolic therapies to reduce cancer risk. Dr. D’Agostino shares the critical tests we should focus on to assess our metabolic health and the essential supplements that can support ketosis. 

Dr. Dominic D’Agostino is an Assistant Professor at the University of South Florida College Of Medicine, Molecular Pharmacology & Physiology, where he develops and tests metabolic therapies, including alternative energy substrates and ketogenic agents for neurological disorders, cancer, and wound healing. While studying the effects of gasses on the brains of Navy Seal divers, he developed an approach for metabolically starving cancer cells through diet and compressed oxygen, replacing chemotherapy, surgery, or radiation.  

In this episode, Dhru and Dr. D’Agostino dive into (audio version / Apple Subscriber version):

The most innovative approaches to cancer (00:00:11 / 00:00:11) 

The metabolic approach to cancer (1:30/1:30)

Using the hyperbaric approach in cancer patients (13:00/ 9:03)

The results of Dr. A’gostino’s studies on mice (17:00 / 13:50)

How this research translates to patients (22:00 / 18:05)

Why a ketogenic diet can be therapeutic (37:00 / 32:04)

The role of exercise in cancer prevention (53:00 / 46:35)

What lifestyle factors should we be doubling down on for prevention (55:00 / 50:14)

Dr. D’Agostino’s thoughts on a low carbohydrate diet (1:01:00 / 56:30)

The therapeutic benefits of ketosis (1:11:00 / 1:06:40)

Supplements that can support ketosis (1:19:00 / 1:12:43)

How to measure for ketosis (1:24:00 / 1:18:30)

Checking the status of your metabolic health (1:26:00 / 1:21:30)

Where to find community (1:34:00 / 1:28:16)


Also mentioned in this episode:

Keto Start


Donate to the University of Florida (Metabolic Therapy and Cancer Research #250244)

Levels 


To learn more about Dr. D’Agostino, follow him on Instagram, Twitter, or his website. 

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This episode is brought to you by Birch Living, Lifeforce, and Plunge. 

We’ve heard of tests that are used as traditional measures of longevity. Still, a lesser-known but equally important test that should be factored into longevity and long-term independence is VO2 max. This test measures how well your body uses oxygen during exercise, which ultimately translates into how efficiently your body uses oxygen in daily activities as you age. According to today’s guest, increasing VO2 max can significantly reduce your risk of all-cause mortality. 
Today, on the Dhru Purohit Show, Dhru sits down with Dr. Andy Galpin to dive deep into VO2 max and why he believes it is one of the best predictors of longevity. Dr. Galpin breaks down the research behind this test and why it's critical for everyone to know their VO2 max baseline. He also shares why a low VO2 max can cause chronic fatigue, making it challenging to engage in daily activities, and shares his top tips on increasing your VO2 max if you are starting your exercise journey. If you are looking for a deep dive into VO2 Max, this episode is a must-listen. 
Andy Galpin is a tenured professor at California State University, Fullerton. He is the Co-Director of the Center for Sport Performance and Founder/Director of the Biochemistry and Molecular Exercise Physiology Laboratory. He is a Human Performance scientist with a PhD in Human Bioenergetics and over 100 peer-reviewed publications and presentations. He is also a Co-founder of Absolute Rest, BioMolecular Athlete, and RAPID Health & Performance.  
In this episode, Dhru and Dr. Galpin dive into (audio version / Apple Subscriber version):

Why VO2 max is a critical factor in longevity (1:05 / 1:05)

What is VO2 max and getting your baseline (10:00 / 7:05)

Challenges with daily activities that demonstrate a low VO2 max (18:00 / 14:56)

Stimulants and the cycle of fatigue (26:00/ 23:07)

The impact of diet on energy (27:00 / 24:33)

Are smartwatches accurate in calculating VO2 max (32:00 / 26:44)

Methods of testing your VO2 max and guidance on choosing the right test (34:00 / 29:50)

Average and optimal VO2X max levels (39:00 / 34:05)

Increasing your levels and the impact on longevity (47:00 / 42:07)

How to get started in improving your levels (49:00 / 44:53)

How often should you test (55:00 / 50:22)


Also mentioned in this episode:

Dr. Galpin’s Published Work

RAPID Health

Absolute Rest


To learn more about Dr. Galpin, follow him on Instagram, Twitter, or his website. 

To get 20% off your Birch Living mattress plus two free eco-rest pillows, head over to birchliving.com/dhru today.
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This episode is brought to you by Momentous, Lumebox, and Air Doctor.
One in thirty-six children is diagnosed with autism. While 50% of the increase in diagnoses is due to increased awareness about autism, at least 50% of those diagnoses are based on an actual increase in the number of cases. Families navigating this diagnosis can often be inundated with information without proper guidance from a trusted source. Today’s guest, Dr. Suzanne Goh, joins us to break it down.
Today, on the Dhru Purohit Show, Dhru sits down with Dr. Suzanne Goh to dive deep into autism. Dr. Goh shares the factors that can lead to a diagnosis of autism, how it is diagnosed, and what the research shows about brain changes in individuals diagnosed with autism. She also shares the top lifestyle factors, including diet and exercise, that support overall health and brain health after diagnosis, as well as the top myths. Additionally, she shares the research on environmental toxins' role in leading to a diagnosis and the protocol she follows in her clinic to support families.
Dr. Suzanne Goh, MD, BCBA, is cofounder and chief medical officer of Cortica, the largest provider of comprehensive health services for autism in the United States. She is the former Co-Director of Columbia University’s Center for Autism and the Developing Brain, where she researched the biological causes of autism and used brain imaging to identify patterns of neural circuitry and brain chemistry. Dr. Goh is currently a faculty member of the Medical Academy of Pediatric Special Needs and is a frequent speaker for parent advocacy organizations. 
In this episode, Dhru and Dr. Goh dive into (audio version / Apple Subscriber version):

What factors can lead to an autism diagnosis (0:00:07 / 0:00:07)

Is the rise in autism cases related to increased awareness or an increase in actual cases (3:40 / 3:40)

Diagnosing autism and brain changes in children (13:11 / 7:52)

Reducing the risk of an autism diagnosis and what the research shows (17:00 / 13:05)

The role of mitochondrial dysfunction (24:30 / 20:36)

What traditional practitioners believe about autism (31:00 25:15)

Top myths about an autism diagnosis (37:00 / 31:00)

The process and protocol that Dr. Goh’s clinic follows (39:00 / 33:00)

The impact of a whole foods diet on behavior (45:00 / 39:15)

The powerful benefits of exercise and supplements for children with autism (52:00 / 46:16)

Lifestyle factors and improving how the diagnosis is expressed (59:00 / 53:00)

Dr. Goh’s patient stories (1:02:00 / 55:00)

Co-occurring conditions that are common with autism (1:08:00 / 1:01:20)

What role can medications play in the toolbox (1:13:00 / 1:07:00)

The impact of environmental toxins (1:22:00 / 1:16:40)

Final Thoughts (1:31:00/ 1:25:00)


Also mentioned in this episode:
Dr. Goh’s new book, Magnificent Minds 

To learn more about Dr. Goh, follow her on Instagram or her website. 

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This episode is brought to you by BiOptimizers, Lumebox, and AquaTru.
Women can spend up to 40% of their lives in menopause, and we know that they often experience changes in their mood, cognition, and overall brain health during this time. But these changes aren’t discussed openly or discussed with no helpful solutions, leaving women feeling hopeless, alone, or unsupported. Today’s guest is a brain researcher here to shed light on the changes during this time and what we can do to support women entering this phase. 
Today, on the Dhru Purohit Show, Dhru sits down with Dr. Lisa Mosconi to discuss what happens to a woman’s brain when she goes through menopause and the connection to Alzheimer’s disease. Dr. Mosconi shares how to care for women’s brains during puberty, pregnancy, and menopause, how to prevent dementia and the lifestyle habits that can help women navigate the transition into menopause. 
Lisa Mosconi, PhD, is an associate professor of neuroscience in neurology and radiology at Weill Cornell Medicine and the director of the Women’s Brain Initiative and the Alzheimer’s Prevention Clinic at Weill Cornell Medicine/NewYork-Presbyterian Hospital. She is also the New York Times bestselling author of The XX Brain and Brain Food.
 
In this episode, Dhru and Dr. Mosconi dive into (audio version / Apple Subscriber version):

What happens to the brain during menopause (0:00:20 / 0:00:20)

Research as validation for women’s experience (13:40 / 10:40)

Brain changes during the 3Ps in a woman’s life (16:39 / 13:00)

Life contentment during perimenopause and menopause (20:11 / 16:51)

Epigenetic’s role in menopause (26:03 / 22:34)

Lifestyle changes that are critical for optimal brain health (31:15 / 27:45)

Three types of exercise for menopause and what they activate (37:34 / 33:32)

What is menopause and when does perimenopause start (45:06 / 41:18)

Lifestyle factors that cause the early onset of puberty (52:36 / 48:50)

Environmental toxins that Dr. Mosconi removed from her home (57:30 / 53:35)

Whole foods diet, fiber, and protein for optimal health (1:00:00 / 56:08)

The research behind Hormone Replacement Therapy (1:21:32 / 1:17:22)


Also mentioned in this episode:

Dr. Mosconi’s Slideshow 

The Menopause Brain


Go to bioptimizers.com/dhru now and enter promo code DHRU10 to get 10% off any order and up to 2 travel-size bottles of Magnesium Breakthrough for a limited time.
Lumebox is offering my community $260 off their FDA-approved portable Red Light device! That's over 40% off! Go to thelumebox.com/dhru and get your Red Light device. 
AquaTru is a countertop reverse osmosis purifier with a four-stage filtration system that removes 15x more contaminants than the bestselling water filters out there. Go to dhrupurohit.com/filter/ and get $100 off when you try AquaTru for yourself.
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This episode is brought to you by Lifeforce, LMNT, and AquaTru. 
The transition to menopause has historically lacked comprehensive discussion and is often perceived as an abrupt occurrence without recourse. Our guest today has emerged as a vocal advocate, shedding light on the journey from perimenopause to menopause and providing empowering strategies for women navigating this transformative phase.
Today, on the Dhru Purohit Show, Dhru sits down with menopause expert Dr. Mary Claire Haver. Dr. Haver guides us through the myths and misconceptions surrounding perimenopause and menopause. She sheds light on the misguided research and beliefs that contributed to a lack of awareness about this transition for women and the challenges women face during this time. This episode is a must-list for women of any age!
Dr. Mary Claire Haver is board-certified in Obstetrics and Gynecology and is a Certified Culinary Medicine Specialist. In 2021 she opened Mary Claire Wellness, a clinic dedicated to caring for the menopausal patient. She developed the best-selling book and program called The Galveston Diet, a three-pronged lifestyle plan that encourages fuel refocusing, intermittent fasting, and anti-inflammatory nutrition to manage hormonal symptoms, stabilize weight, and revitalize the body as it ages to provide benefits that will last a lifetime.
In this episode, Dhru and Dr. Haver dive into (audio version / Apple Subscriber version):

Why women are living in poorer health later in life (0:00:28 / 0:00:28)

The implications of lack of education about perimenopause and menopause (9:03 / 5:41)

Surprising symptoms related to perimenopause (14:35 / 11:30)

Hormonal changes that cause visceral fat (18:53 / 15:45)

What habits can help women reduce visceral fat (34:11 /29:36)

Protein and resistance training (40:05 / 35:02)

A disruption in sleep quality and sleep apnea in women (43:51 / 38:00)

The stress impact on women (50:50 /45:25)

Gaslighting and lack of education: why women aren’t being heard (56:36 / 51:50)

How menopause impacts gut health(1:01:12 / 56:25)

Supplements to support perimenopause and menopause (1:03:58 / 58:59) 

HRT: Who is it for, how much, and when? (1:15:40 / 1:10:56)


Also mentioned in this episode:

Dr. Haver’s new book, The New Menopause


North American Menopause Society


Right now, you can save $250 on your first diagnostic and get personalized suggestions. Optimize your longevity and track your progress go to mylifeforce.com/dhru! 
Right now, LMNT is offering my listeners a free sample pack with any purchase. Head over to DrinkLMNT.com/dhru today.
AquaTru is a countertop reverse osmosis purifier with a four-stage filtration system that removes 15x more contaminants than the bestselling water filters out there. Go to dhrupurohit.com/filter/ and get $100 off when you try AquaTru for yourself.
Hosted on Acast. See acast.com/privacy for more information.

This episode is brought to you by Lifeforce, BiOptimizers, and Lumebox.
We are constantly bombarded with the newest technology or hacks that can increase our longevity. But when it comes to true health and disease prevention, we know that consistently putting effort into our daily habits can have the most effective results. Today’s guest is here to remind us which daily habits matter the most.  
Today, on The Dhru Purohit Show, Dhru sits down with Dr. Darshan Shah to discuss the pillars of the Shah Protocol. Dr. Shah emphasizes the significance of dialing in the basics: sleep, diet, and movement. He also shares the ten blood markers everyone should obtain and truly understand. Dr. Shah also discusses the tools he uses to assess and reduce the risk of chronic disease and increase longevity and shares his journey to becoming healthier. 
Darshan Shah, MD, is a health and wellness specialist, board-certified surgeon, published author, entrepreneur, and founder of Next Health, the world's first and largest Health Optimization and Longevity clinic.
 
In this episode, Dhru and Dr. Shah dive into (audio version / Apple Subscriber version):

The first step in Dr. Shah’s protocol (0:00:29 / 0:00:29)

One habit that would change energy levels (3:33 / 3:33)

Setting up your ideal sleep routine in the morning (11:53 / 11:53)

What Dr. Shah has doubled down on and what he no longer prioritizes (25:39 / 21:35)

Dr. Shah’s journey to become healthier (31:20 / 25:54)

Eating whole foods and finding what works for you (37:10 / 31:41)

The benefits of fiber for your microbiome (41:30 / 35:48)

Metabolically fit individuals with higher A1C levels (48:45 / 43:35)

Ten blood markers that must be checked (51:12 / 45:27)

The importance of moving each day (1:08:42 / 1:03:00)

Preventing osteoporosis and osteopenia (1:15:57 / 1:11:59)

VO2 Max as a longevity assessment (1:19:45 / 1:14:40)

Heart disease and early cancer detection screenings (1:27:09 / 1:21:30)


Also mentioned in this episode:

Microplastics and Nanoplastics in Atheromas and Cardiovascular Events

Dhru’s apoB results

Next Health 


Right now, you can save $250 on your first diagnostic and get personalized suggestions. Optimize your longevity and track your progress go to mylifeforce.com/dhru! 
Go to bioptimizers.com/dhru now and enter promo code DHRU10 to get 10% off any order and up to 2 travel-size bottles of Magnesium Breakthrough for a limited time. 
Lumebox is offering my community $260 off their FDA-approved portable Red Light device! That's over 40% off! Go to thelumebox.com/dhru and get your Red Light device.
Hosted on Acast. See acast.com/privacy for more information.