In this comprehensive discussion, Dr. Claire Merrifield delves into the intricacies of the endocrine system, explaining the structure and function of various glands and hormones. The conversation touches on the hormone production process, the interplay between the endocrine and nervous systems, and the impact of hormones on bodily functions. Key topics include thyroid health, cortisol levels, the role of stress, and hormone replacement therapies for both men and women. Dr. Merrifield also sheds light on common misconceptions related to hormonal health, emphasizing the importance of managing stress and maintaining a balanced lifestyle for overall well-being. Dr Claire Merrifield MBBS MRCGP PhD | Co-Founder & Medical Director, Selph Claire is a GP, microbiome researcher and trained mindfulness instructor who brings a rare blend of clinical experience, scientific expertise and real-world empathy to modern healthcare. She’s the Medical Director of Selph, and the heart of its mission: to help people take back control of their own health, with guidance that’s holistic, practical and grounded in science. Claire completed her medical training at Imperial College London, where she later undertook a PhD exploring the link between gut microbes and the immune system. Her research has focused on probiotics, nutrition, immunology and the prevention of chronic illness. As a GP, Claire has supported thousands of patients in understanding their bodies, navigating the healthcare system and making sustainable lifestyle changes — especially women’s health, burnout, and gut-brain connection. Claire is also a certified Breathworks Mindfulness instructor, adding depth and compassion to her clinical approach. With her unique ability to bridge science and everyday life, Claire is on a mission to make proactive healthcare more accessible, inclusive and empowering. Dr. Merrifield's Links: www.selph.co.uk https://www.linkedin.com/in/clairemerrifield/ https://www.instagram.com/selphhealthuk/ claire@selph.co.uk Learn More about Dr. Darian: Website: https://doctordarianparker.com/ LinkedIn: https://www.linkedin.com/in/darianparker/ Dr. Darian's Affiliates: Relax the Back Relax The Back® embraces a holistic approach for a healthier lifestyle grounded in 40 years of proven expertise. Live wellness is our commitment to helping you transform your routine, your space, and your life, with solutions that elevate your physical and mental well-being. Use this link: Relax the Back level up your well being. Blumaka Run better. Move smarter. Save 20%.Blumaka insoles are built for performance and sustainability, offering elite-level cushioning, grip, and durability with up to 85% recycled foam. Use code FSF20 for 20% off: https://blumakastore.myshopify.com/discount/FSF20 Stick Mobility Get your flexibility back and prevent injuries with Stick Mobility. Training Sticks improve range of motion, muscle activation, coordination, and body awareness to build a strong foundation for better movement. Go to this Link or copy to your browser https://stickmobility.com/darian-parker and use the discount code: 1CEC828F154 to get 10% off of your purchase. Chapters: 00:00 Introduction to the Endocrine System 00:54 Hormones and Their Functions 03:15 Brain's Role in Hormone Production 05:31 Thyroid and Parathyroid Glands 07:15 Gastrointestinal Hormones 09:47 Kidneys and Adrenal Glands 12:21 Sex Hormones and Fat's Role 15:26 Thyroid Dysfunction and Weight Loss 19:25 Optimizing Thyroid Function 24:00 Medication Resistance and Hormone Myths 28:42 Complexity of the Human Body 31:05 Exploring Endocrine System Dysfunction and Heritability 33:44 Understanding Cortisol: The Stress Hormone 37:21 The Impact of Stress on Health and Wellbeing 41:54 Inflammation and Aging: The Hidden Connection 45:27 The Importance of Self-Care and Mindfulness 52:29 Hormone Replacement Therapy: Estrogen and Testosterone