46: Insulin Resistance, Lyme Disease, + The Nocebo Effect | Jim LaValle

Hey Functional Friends, welcome back to the Holistic Savage Podcast! Today’s episode is extra special because I’m sitting down with Jim LaValle, a total legend in the functional medicine world and someone I’ve admired since my early days with Lifetime Fitness. Jim’s now the chief scientific officer at Lifetime and his resume in this space is seriously off the charts. We explore the evolution of functional medicine, how fitness plays a role, and all the juicy details on making informed clinical decisions. Plus, we tackle everything from the nocebo effect to optimizing performance health and even peptides for chronic disease. Buckle up, it’s gonna be a wild ride!

Topics Discussed:

• 05:15 - The evolution of functional medicine 

• 16:02 - Fitness and functional medicine 

• 19:40 - Making informed clinical decisions & functional testing 

• 29:03 - “Everything is gonna be Lyme if you specialize in Lyme” 

• 31:07 - Getting lost in the data points 

• 34:59 - The nocebo effect & our limbic system 

• 42:37 - Running a mini clinical trial 

• 54:02 - Monitoring your labs 

• 58:02 - Markers to look out for 

• 01:00:30 - Optimizing performance health 

• 01:06:48 - Peptides for chronic disease and where to source them 

Further Listening:

• 42: Thoughts Become Proteins | Solo Episode

Sponsored By:

• DHA Labs

• Learn more about DHA Laboratory

• Metabolic Solutions Research & Education Foundation 

• T-Shirt Fundraiser

• Microbiome Labs 

• Check out Microbiome Labs Today

• Berkeley Life

• For Self-Healers

• For Providers

Check Out Jim LaValle

• Website

• Instagram

Check Out Brendan:

• Brendan’s Instagram: @the_holistic_savage
• Brendan Online

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Produced By: Drake Peterson

Edited By: Mike Frey