7 episodes

Chris and Xand are doctors, scientists and identical twins. Well, not quite identical. Xand is 20kg heavier, clinically obese, and has a Covid induced heart condition. 
The reason Xand is overweight is the same reason that most of us in the UK are overweight: Ultra Processed Food or UPF.  
It’s the main thing that we now eat (and feed to our children), but most of us have never heard of it. It’s addictive, highly profitable and the main cause of the global obesity pandemic. It’s destroying our bodies, our brains and the environment. 
Chris wants Xand to quit so he has a plan: to send him on a journey to meet the world’s leading experts on food, weight, taste and addiction whilst encouraging a final UPF binge in a bid to see if he can learn to hate it. 
Simple right? Well it turns out to be way stranger and more emotional than either of them ever imagined...

An episode will drop each Tuesday from July 6, 2021 for 6 weeks.


See acast.com/privacy for privacy and opt-out information.

A Thorough Examination with Drs Chris and Xand Loftus Media / Van Tulleken Brothers Ltd

    • Health & Fitness
    • 4.8 • 27 Ratings

Chris and Xand are doctors, scientists and identical twins. Well, not quite identical. Xand is 20kg heavier, clinically obese, and has a Covid induced heart condition. 
The reason Xand is overweight is the same reason that most of us in the UK are overweight: Ultra Processed Food or UPF.  
It’s the main thing that we now eat (and feed to our children), but most of us have never heard of it. It’s addictive, highly profitable and the main cause of the global obesity pandemic. It’s destroying our bodies, our brains and the environment. 
Chris wants Xand to quit so he has a plan: to send him on a journey to meet the world’s leading experts on food, weight, taste and addiction whilst encouraging a final UPF binge in a bid to see if he can learn to hate it. 
Simple right? Well it turns out to be way stranger and more emotional than either of them ever imagined...

An episode will drop each Tuesday from July 6, 2021 for 6 weeks.


See acast.com/privacy for privacy and opt-out information.

    Building an ultra processed world

    Building an ultra processed world

    Marion Nestle explains how UPF is not just a public health issue, it's an environmental disaster. She considers / recommends what needs to be done to combat the rocketing levels of obesity whilst ensuring sustainable healthy food production. 
    Xand finishes the experiment...is he still addicted to UPF?
    Warning: This episode contains strong language.

    See acast.com/privacy for privacy and opt-out information.

    • 29 min
    Building an ultra processed mind

    Building an ultra processed mind

    Xand continues the experiment and speaks to Dr Nicole Avena, food addiction neurologist, about how our brains are affected by UPF in relation to other addictive behaviour. 
    Both Chris and Xand also speak to sensory expert, Professor Barry Smith from The University of London about how all of our senses are targeted by companies when we consume their UPF products.


    See acast.com/privacy for privacy and opt-out information.

    • 30 min
    Building an ultra processed body

    Building an ultra processed body

    Xand starts an experiment, eating an 80% UPF diet whilst continuing to learn about it. He speaks to obesity expert, Dr Janine Makaronidis from University College London about the food’s direct effect on his body, what it will do to his appetite, hormones and weight. 
    He also interviews Dr Kevin Hall from the National Institute of Health in the US about his ground-breaking research into the consumption of UPF - Kevin was the first to prove that UPF causes weight gain.


    See acast.com/privacy for privacy and opt-out information.

    • 27 min
    How to change? Let it go...

    How to change? Let it go...

    Chris and Xand have an emotional conversation about why this project is important and hard for both of them. They speak separately to Alasdair Cant, a behaviour change expert, about how we decide to become different people. 
    Alasdair also speaks to Chris about how he, like many family members, may be holding Xand back.
    Warning: This episode contains strong language.


    See acast.com/privacy for privacy and opt-out information.

    • 31 min
    UPF is not food

    UPF is not food

    Chris and Xand meet Professor of Chemistry Andrea Sella to try to understand some of the more complex ingredients in Ultra Processed Food aka UPF and the lies they tell us about when we are full and satisfied.
    Dr Fernanda Rauber was on the team who "discovered" UPF, and explains why it exists and that perhaps we are thinking about it in the wrong way. It's not food - it's an industrial formulation of chemicals.
    Warning: This episode contains strong language.


    See acast.com/privacy for privacy and opt-out information.

    • 29 min
    How did we get so different?

    How did we get so different?

    Chris and Xand have the same genes but the largest weight difference of any twin pair studied in the UK. What happened? 
    They speak to friend and geneticist Dr Giles Yeo to begin to understand the origins of Xand's (and everyone else's) size. How much is destiny, how much might we be able to control?
    (Many thanks to Little Gem TV for the use of a clip from the 2020 documentary, 'Surviving the Virus: My Brother, Covid and Me').

    See acast.com/privacy for privacy and opt-out information.

    • 33 min

Customer Reviews

4.8 out of 5
27 Ratings

27 Ratings

Arp121 ,

Thoroughly Excellent

I learned so much. Touching. Brilliant. Fascinating. Original.

CreevyC ,

stop chewing on the podcast GROSS

ohmygod this would have been fine but how completely disgusting it is to hear people CHEWING directly into your ears absolutely ruins this show. It is NASTY and I hate everything about this now. F-cking grossssss never again. Two episodes in and I am done. EW.

SunriseSurprise ,

Loved This!

I truly enjoyed listening to this series. Funny yet filled with truths about what we are eating and the scientific studies that prove how the ultra processed foods have such a negative effect on our health and all the $ companies make when we all become addicted. Excellent and well worth your time if you are struggling with your weight and wondering why you can’t stop eating crap food.

Top Podcasts In Health & Fitness

You Might Also Like